N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide
CAS:
Ref. TR-H114085
1g
784.00€
5g
2,987.00€
500mg
417.00€
Product Information
Name:N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide
Controlled Product
Brand:TRC
Description:Applications N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide is an intermediate in the synthesis of NSC 23766 (N900280), which is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.
References Gao, Y., et. al.: Proc. Natl. Acad. Sci. U.S.A., 101, 7618, (2004); Akbar, H., et. al.: Methods Enzymol, 406, 554 (2006)
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Chemical properties
Molecular weight:216.24
Formula:C12H12N2O2
Color/Form:Neat
InChI:InChI=1S/C12H12N2O2/c1-7-5-12(16)10-6-9(14-8(2)15)3-4-11(10)13-7/h3-6H,1-2H3,(H,13,16)(H,14,15)
InChI key:InChIKey=INGXYDNOMOPBLY-UHFFFAOYSA-N
SMILES:CC(=O)Nc1ccc2nc(C)cc(O)c2c1
Technical inquiry about: N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide
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