Product Information
Name:6-Hydroxy Dopamine Hydrobromide
Controlled Product
Synonyms:
- 5-(2-aminoethyl)benzene-1,2,4-triol;hydrobromide
Brand:TRC
Description:Stability Hygroscopic, Light Sensitive
Applications 6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells.
References Soto-Otero, R. et al.: J. Neurochem., 74, 1605 (2000); Fujita, H. et al.: Brain Res., 1113, 10 (2006); Breese, G.R. et al.: 174, 313 (1970);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:250.09
Formula:C8H11NO3·BrH
Color/Form:Neat
InChI:InChI=1S/C8H11NO3.BrH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H
InChI key:InChIKey=MLACDGUOKDOLGC-UHFFFAOYSA-N
SMILES:Br.NCCc1cc(O)c(O)cc1O
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