4-Hydroxy Nebivolol, Hydrochloride Hydrate(Mixture of Diastereomers)
CAS:
Ref. TR-H948530
5mg
4,964.00€
500µg
624.00€
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Product Information
Name:4-Hydroxy Nebivolol, Hydrochloride Hydrate(Mixture of Diastereomers)
Synonyms:
- 6-Fluoro-a-[[[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]amino]methyl]-3,4-dihydro-4-hydroxy-2H-1-benzopyran-2-methanol Hydrochloride Hydrate
Brand:TRC
Description:Stability Hygroscopic
Applications A metabolite of Nebivolol.
References Stoleru, L., et al.: J. Cardiovasc. Pharmacol., 22, 183 (1993), Cockcroft, J., et al.: J. Pharmacol. Exp. Ther., 274, 1067 (1995), Stoschitzky, K., et al.: Cardiovasc. Drugs Ther., 16, 133 (2002), Poole-Wilson, P., et al.: Lancet, 362, 7 (2003),
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Chemical properties
Molecular weight:475.91
Formula:C22H28ClF2NO6
Color/Form:Neat
InChI:InChI=1S/C22H25F2NO5.ClH.H2O/c23-13-2-5-19-12(7-13)1-4-21(29-19)17(27)10-25-11-18(28)22-9-16(26)15-8-14(24)3-6-20(15)30-22;;/h2-3,5-8,16-18,21-22,25-28H,1,4,9-11H2;1H;1H2
InChI key:InChIKey=NNLYRGGZJNHZRC-UHFFFAOYSA-N
SMILES:Cl.O.OC1CC(C(O)CNCC(O)C2CCc3cc(F)ccc3O2)Oc2ccc(F)cc21
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