Product Information
Name:(R)-Irofulven
Controlled Product
Synonyms:
- (6'R)-6'-Hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one
- (-)-(Hydroxymethyl)acylfulvene
- (-)-Irofulven
- HMAF
- MGI 114
- NSC 683863
Brand:TRC
Description:Applications Semi-synrhetic antitumor agent derived from Illudin S. Inhibits DNA synthesis and induces apoptosis in tumor cells. Antineoplastic.
References Woynarowski, J.M., et al.: Biochem. Pharmacol., 54, 1181 (1997), Alexandre, J., et al.: Clin. Cancer Res., 10, 3377 (2004), Senzer, N., et al.: Am. J. Clin. Oncol., 28, 36 (2005),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:246.31
Formula:C15H18O3
Color/Form:Neat
InChI:InChI=1S/C15H18O3/c1-8-6-10-12(11(8)7-16)9(2)15(4-5-15)14(3,18)13(10)17/h6,16,18H,4-5,7H2,1-3H3/t14-/m0/s1
InChI key:InChIKey=NICJCIQSJJKZAH-AWEZNQCLSA-N
SMILES:CC1=C(CO)C2=C(C)C3(CC3)[C@@](C)(O)C(=O)C2=C1
Technical inquiry about: (R)-Irofulven
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