Product Information
Name:(S)-Isopropyl-2-aminopropanoate-d7 Hydrochloride
Controlled Product
Synonyms:
- L-Alanine 1-(Methyl-d3)ethyl-1,2,2,2-d4 Ester Hydrochloride (1:1)
Brand:TRC
Description:Applications (S)-Isopropyl-2-aminopropanoate-d7 Hydrochloride is an intermediate in the synthesis of Desphenyl Tenofovir Alafenamide-d7 Ammonium Salt (D297044). Desphenyl Tenofovir Alafenamide-d7 Ammonium Salt is labeled form of Desphenyl Tenofovir Alafenamide (D297043), which belongs to a group of tenofovir diesters compounds, which can inhibit HIV-1 virus replication. Desphenyl Tenofovir Alafenamide can also be used to investigate the effect of oral absorption and lymphoid cell loading of GS-7340 (a prodrug of tenofovir). (S)-Isopropyl-2-aminopropanoate-d7 Hydrochloride is also the labelled form of (S)-Isopropyl-2-aminopropanoate Hydrochloride (I822220), which is a chemical reagent used in the synthesis of anti-HCV prodrugs based on imidazotriazine and pyrrolotriazine molecules.
References You, G., et al.: PCT Int. Appl. WO 2014026582 A1 2014022 (2014); Babusis, D., et al.: Mol. Pharm. 10, 459 (2013); Tyndall, E. Bioorg. Med. Chem. Lett., 25, 869 (2015)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:174.68
Formula:C6H6D7NO2·HCl
Color/Form:Neat
InChI:InChI=1S/C6H13NO2.ClH/c1-4(2)9-6(8)5(3)7;/h4-5H,7H2,1-3H3;1H/t5-;/m0./s1/i1D3,2D3,4D;
InChI key:InChIKey=YAQKNCSWDMGPOY-SAADNGMHSA-N
SMILES:Cl.[2H]C([2H])([2H])C([2H])(OC(=O)[C@H](C)N)C([2H])([2H])[2H]
Technical inquiry about: (S)-Isopropyl-2-aminopropanoate-d7 Hydrochloride
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