Product Information
Name:IWP-2
Synonyms:
- N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]acetamide
Brand:TRC
Description:Applications IWP-2 is an inactivator of Porcn function; inhibitor of Wnt production. IWP-2 is useful in the treatment diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosis.
References Poss, K., et al.: Dev. Biol., 222, 347 (2000), Tanaka, K., et al.: Eur. J. Biochem., 267, 4300 (2000), Clevers, H., et al.: Cell, 2006, 127, 469 (2006),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:466.60
Formula:C22H18N4O2S3
Color/Form:Off White Powder
InChI:InChI=1S/C22H18N4O2S3/c1-13-7-8-15-17(11-13)31-21(23-15)25-18(27)12-30-22-24-16-9-10-29-19(16)20(28)26(22)14-5-3-2-4-6-14/h2-8,11H,9-10,12H2,1H3,(H,23,25,27)
InChI key:InChIKey=WRKPZSMRWPJJDH-UHFFFAOYSA-N
SMILES:Cc1ccc2nc(NC(=O)CSc3nc4c(c(=O)n3-c3ccccc3)SCC4)sc2c1
Technical inquiry about: IWP-2
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