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Metformin Hydrochloride

CAS:

Ref. TR-M258815

1g
114.00€
5g
121.00€
100g
296.00€
Metformin Hydrochloride
TRC

Product Information

Name:Metformin Hydrochloride
Controlled Product
Synonyms:
  • Imidodicarbonimidic diamide
  • N,N-dimethyl-
  • hydrochloride (1:1)
  • Biguanide
  • 1,1-dimethyl-
  • hydrochloride (6CI)
  • Biguanide
  • 1,1-dimethyl-
  • monohydrochloride (8CI)
  • Imidodicarbonimidic diamide
  • N,N-dimethyl-
  • See more synonyms
Brand:TRC
Description:Applications An oral hypoglycemic agent. Slows electron transport in the oxidation pathway in mitochondria. Has been reported to reverse Lupus symptoms in mice in conjunction with 2-deoxy-d-glucose (D239000). Metformin is a well-known type 2 diabetes treatment. Research shows that metformin may inhibit tumor growth both directly and indirectly. Studies indicate that metformin modulates the biology of aging. Metformin blocks the conversion of select substrates into glucose in a redox-dependent manner. References Tucker, G.T., et al.: Brit. J. Clin. Pharmacol., 12, 235 (1981), DeFronzo, R.A., et al.: N. Engl. J. Med., 333, 541 (1995); Chem. and Eng. News, page 7, Feb. 23 (2015); Nir Barzilai et al., Cell Metabolism 23: 1060 June 14 (2016); Chem. and Eng. News, page 7, Feb. 23 (2015); Chem. and Eng. News, page 12, July 30 (2018)
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Chemical properties

Molecular weight:165.62
Formula:C4H11N5·ClH
Color/Form:White
InChI:InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
InChI key:InChIKey=OETHQSJEHLVLGH-UHFFFAOYSA-N
SMILES:CN(C)C(=N)NC(=N)N.Cl

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