Product Information
Name:3-O-Methyl-L-DOPA Monohydrate
Synonyms:
- (2S)-2-amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid;hydrate
Brand:TRC
Description:Applications 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA.
References Soares-da Silva, P., et al.: Brain Res., 863, 293 (2000), Deleu, D., et al.: Clin. Pharmacokinet., 41, 261 (2002),
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Chemical properties
Molecular weight:229.23
Formula:C10H13NO4·H2O
Color/Form:Neat
InChI:InChI=1S/C10H13NO4.H2O/c1-15-9-5-6(2-3-8(9)12)4-7(11)10(13)14;/h2-3,5,7,12H,4,11H2,1H3,(H,13,14);1H2/t7-;/m0./s1
InChI key:InChIKey=IDRRCKUGGXLORG-FJXQXJEOSA-N
SMILES:COc1cc(C[C@H](N)C(=O)O)ccc1O.O
Technical inquiry about: 3-O-Methyl-L-DOPA Monohydrate
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