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2-Methyl-1-[(3-nitro-4-quinolinyl)amino]-2-propanol

CAS:

Ref. TR-M323783

1g
656.00€
250mg
209.00€
500mg
362.00€
2-Methyl-1-[(3-nitro-4-quinolinyl)amino]-2-propanol
TRC

    Product Information

    Name:2-Methyl-1-[(3-nitro-4-quinolinyl)amino]-2-propanol
    Controlled Product
    Synonyms:
    • 2-Methyl-1-[(3-nitroquinolin-4-yl)amino]propan-2-ol
    • N-(2-Hydroxy-2-methylpropyl)-3-nitroquinolin-4-amine
    Brand:TRC
    Description:Applications 2-Methyl-1-[(3-nitro-4-quinolinyl)amino]-2-propanol is an intermediate in synthesizing Resiquimod-d5 (R144682), an isotope labelled Resiquimod (R144680) which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist. References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);
    Notice:Our products are intended for lab use only. For any other use, please contact us.

    Chemical properties

    Molecular weight:261.28
    Formula:C13H15N3O3
    Color/Form:Neat
    InChI:InChI=1S/C13H15N3O3/c1-13(2,17)8-15-12-9-5-3-4-6-10(9)14-7-11(12)16(18)19/h3-7,17H,8H2,1-2H3,(H,14,15)
    InChI key:InChIKey=NHMKYUHMPXBMFI-SNVBAGLBSA-N
    SMILES:C=CC(=C)C[C@H](O)C=C(C)C

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