- Food Industry Standards
- Miscellaneous Organic Molecules with Isotopical Substitutions
- Deuterated Compounds
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)
Product Information
Name:6-Methylthioguanine-d3
Controlled Product
Synonyms:
- 6-(Trideuteriomethylsulfanyl)-7H-purin-2-amine
- 6-Methylthioguanine-D3 (methyl-D3)
- 2-Amino-6-(methyl-d3)thiopurine
- 6-Trideuteromethylthioguanine
Brand:TRC
Description:Applications A labelled metabolite of 2’-Deoxy-6-thio Guanosine (D281650) and 6-Thioguanine. An effective immunosuppressant and anticancer agent, however chronic exposure can be mutagenic in human cells as long-term use of thiopurines was found to be associated with a significantly increased risk of various types of cancer.
References Loo, T.L. et al.: Cancer Chemother. Pharmacol., 6, 131 (1981); Yuan, B. et al.: ACS Chem. Biol., 5, 1021 (2010); Kroplin, T. et al.: Adv. Exp. Med. Biol., 431, 741 (1998);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:184.24
Formula:C62H3H4N5S
Color/Form:Neat
InChI:InChI=1S/C6H7N5S/c1-12-5-3-4(9-2-8-3)10-6(7)11-5/h2H,1H3,(H3,7,8,9,10,11)/i1D3
InChI key:InChIKey=YEGKYFQLKYGHAR-FIBGUPNXSA-N
SMILES:[2H]C([2H])([2H])Sc1nc(N)nc2nc[nH]c12
Technical inquiry about: 6-Methylthioguanine-d3
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