- Pharmaceutical Standards
- Antivirals
- Toxicology
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)
Product Information
Name:Mono-POC Tenofovir
Synonyms:
- 2,4,7-Trioxa-5-phosphanonanoic acid
- 9-(6-amino-9H-purin-9-yl)-5-hydroxy-8-methyl-
- 1-methylethyl ester
- 5-oxide
- (8R)-
- Tenofovir monoisoproxil
Brand:TRC
Description:Stability Hygroscopic
Applications An impurity of Tenofovir Disoproxil (T018505(P)), which is an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. It is used as an anti-HIV agent and an antiviral.
References Gan, L., et al.: Drug Metab. Dispos., 24, 344 (1996), Annaert, P., et al.: Pharm. Res., 14, 492 (1997), Naesens, L., et al.: Antimicrob. Agents Chemother., 42, 1568 (1998), Shaw, J. P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:403.33
Formula:C14H22N5O7P
Color/Form:White To Light Beige
InChI:InChI=1S/C14H22N5O7P/c1-9(2)26-14(20)23-7-25-27(21,22)8-24-10(3)4-19-6-18-11-12(15)16-5-17-13(11)19/h5-6,9-10H,4,7-8H2,1-3H3,(H,21,22)(H2,15,16,17)/t10-/m1/s1
InChI key:InChIKey=XLYSRKLPLHUWCJ-SNVBAGLBSA-N
SMILES:CC(C)OC(=O)OCOP(=O)(O)CO[C@H](C)Cn1cnc2c(N)ncnc21
Technical inquiry about: Mono-POC Tenofovir
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