Product Information
Name:SP 2509
Controlled Product
Synonyms:
- 3-(4-Morpholinylsulfonyl)-Benzoic Acid (2E)-2-[1-(5-chloro-2-hydroxyphenyl)ethylidene]hydrazide
- BHC 110 inhibitor VII
- Histone Lysine Demethylase Inhibitor XIV
- KIAA 1718 inhibitor VII
- LSD 1 inhibitor VII
Brand:TRC
Description:Applications SP 2509 reduces the effect of the LSD1 binding to CoREST, resulting in increased methylation of H3K4 and driving increased expression of p21, p27 and CCAAT/enhancer binding protein α in acute myeloid leukemia cells. Anti-leukemia agent.
References Sorna, V. et al.: J. Med. Chem., 56, 9496 (2013); Fiskus, W. et al.: Leukemia, 11, 2155 (2014);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:437.9
Formula:C19H20ClN3O5S
Color/Form:Neat
InChI:InChI=1S/C19H20ClN3O5S/c1-13(17-12-15(20)5-6-18(17)24)21-22-19(25)14-3-2-4-16(11-14)29(26,27)23-7-9-28-10-8-23/h2-6,11-12,24H,7-10H2,1H3,(H,22,25)/b21-13+
Technical inquiry about: SP 2509
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