1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one (Ondansetron Impurity G)
CAS:
Ref. TR-T293715
10mg
361.00€
50mg
1,456.00€
100mg
2,352.00€
Product Information
Name:1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one (Ondansetron Impurity G)
Controlled Product
Synonyms:
- Ondansetron Hydrochloride Dihydrate Imp. G (EP)
- Ondansetron Imp. G (EP)
- (3RS)-3-[(1H-Imidazol-1-yl)methyl]-9-methyl-1,2,3,9-tetrahydro-4H-carbazol-4-one
- C-Demethylondansetron
- Ondansetron Hydrochloride Dihydrate Impurity G
- Ondansetron Impurity G
Brand:TRC
Description:Applications 1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one is an metabolite of Ondansetron (O655000), is a selective 5-hydroxytryptamine3 (5-HT3) receptor antagonist that has been introduced to clinical practice as an antiemetic for cancer treatment-induced and anesthesia-related nausea and vomiting.
References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000), Ye, J.H., et al.: CNS Drug Reviews., 7, 199 (2001);
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Chemical properties
Molecular weight:279.34
Formula:C17H17N3O
Color/Form:White To Off-White
InChI:InChI=1S/C17H17N3O/c1-19-14-5-3-2-4-13(14)16-15(19)7-6-12(17(16)21)10-20-9-8-18-11-20/h2-5,8-9,11-12H,6-7,10H2,1H3
InChI key:InChIKey=KPSGSRBENRBWPG-UHFFFAOYSA-N
SMILES:Cn1c2c(c3ccccc31)C(=O)C(Cn1ccnc1)CC2
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