(3Beta,5Beta,7Alpha,12Alpha,24E)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid
Ref. TR-T887995
5mg
444.00€
10mg
832.00€
2500µg
237.00€
Product Information
Name:(3Beta,5Beta,7Alpha,12Alpha,24E)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid
Controlled Product
Brand:TRC
Description:Applications (3β,5β,7α,12α,24E)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid is an intermediate in the synthesis of (25R)-3β,7α,12α-Trihydroxy-5-cholestenoic Acid (T795130), which is an oxysterol, an oxidized derivatives of cholesterol (C432501), which may be important in many biological processes, including cholesterol homeostasis, atherosclerosis, sphingolipid metabolism, platelet aggregation, apoptosis, and protein prenylation,[1] though their roles are poorly understood.
References Schroepfer, G., et al.: Physiol. Rev., 80, 361 (2000); Bjorkhem, I.: J. Clin. Invest., 6, 725(2002); Bjorkhem, I., et al.: Arterio. hromb. Vascul. Biol., 22, 734 (2002)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:448.64
Formula:C27H44O5
Color/Form:Neat
InChI:InChI=1S/C27H44O5/c1-15(6-5-7-16(2)25(31)32)19-8-9-20-24-21(14-23(30)27(19,20)4)26(3)11-10-18(28)12-17(26)13-22(24)29/h7,15,17-24,28-30H,5-6,8-14H2,1-4H3,(H,31,32)/b16-7+/t15-,17+,18+,19-,20?,21?,22-,23+,24?,26+,27-/m1/s1
InChI key:InChIKey=VXQOOUCCLSSSSV-VKELCSSASA-N
SMILES:C/C(=C\CC[C@@H](C)[C@H]1CCC2C3C(C[C@H](O)[C@@]21C)[C@@]1(C)CC[C@H](O)C[C@H]1C[C@H]3O)C(=O)O
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