Product Information
Name:Trovafloxacin
Controlled Product
Synonyms:
- 7-((1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-1,8-naphthyridine-3-carboxylic Acid
- Turvel
- 3-Azabicyclo[3.1.0]hexane
- 1,8-naphthyridine-3-carboxylic acid derivative
- 7-[(1alpha,5alpha,6alpha)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid
Brand:TRC
Description:Applications Trovafloxacin is a fluroquinolone antibiotic, recently identified as an inhibitor of pannexin-1 (Panx1) channels. Trovafloxacin attenuates neuroinflammation and improves outcome after traumatic brain injury in mice.
References Garg, C., et al.: J. Neuroinflammation, 15, 42 (2018); Angus, J. A., et al.: Eur. J. Pharmacol., 791, 179 (2016)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:402.37
Formula:C20H15F3N4O3
Color/Form:Neat
InChI:InChI=1S/C20H15F3N4O3/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24/h1-4,7,10-11,16H,5-6,24H2,(H,29,30)/t10-,11+,16+
InChI key:InChIKey=WVPSKSLAZQPAKQ-CDMJZVDBSA-N
SMILES:N[C@H]1[C@@H]2CN(c3nc4c(cc3F)c(=O)c(C(=O)O)cn4-c3ccc(F)cc3F)C[C@H]12
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