Product Information
Name:VU 0365114
Controlled Product
Synonyms:
- 1-([1,1'-Biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)-1H-indole-2,3-dione
Brand:TRC
Description:Applications VU 0365114 is a selective positive allosteric modulator of M5 (EC50 values are 2.7 μM for human M5, and >30 μM for M1, M2, M3 and M4 receptors).
References Bridges, T.M., et al.: Bioorg. Med. Chem. Lett., 20, 5617 (2010);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:397.347
Formula:C22H14F3NO3
Color/Form:Neat
InChI:InChI=1S/C22H14F3NO3/c23-22(24,25)29-17-10-11-19-18(12-17)20(27)21(28)26(19)13-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-12H,13H2
InChI key:InChIKey=SPBGRXOPAXZSER-UHFFFAOYSA-N
SMILES:O=C1C(=O)N(Cc2ccc(-c3ccccc3)cc2)c2ccc(OC(F)(F)F)cc21
Technical inquiry about: VU 0365114
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