CAS: 100111-07-7

GNRH precursor (14-26) is a peptide that is important for the regulation of reproduction and fertility. It has been shown to activate the receptor in living cells, where it signals through G-protein coupled receptors. GNRH precursor (14-26) has also been shown to have an inhibitory effect on the activity of certain ion channels and can be used as a research tool in cell biology or pharmacology, as well as an antibody production reagent. GNRH precursor (14-26) is also known as Gonadotropin releasing hormone, GnRH or LHRH. The peptide consists of 14 amino acids and is classified as a class II signal peptide. It is synthesized by neurons in the hypothalamus and transported down axons to the pituitary gland where it stimulates release of hormones necessary for sexual development and reproductive function. GNRH precursor (14-26) binds with high affinity to the GnRH receptor present in cells that regulate