CAS 207399-07-3: IR 780
Descrição:
IR 780, com o número CAS 207399-07-3, é um corante fluorescente de infravermelho próximo (NIR) que é utilizado principalmente em aplicações de imagem biológica e terapia fototérmica. Este composto exibe forte absorção na região do infravermelho próximo, o que permite uma penetração mais profunda nos tecidos e reduz a fluorescência de fundo, tornando-o particularmente útil em diagnósticos médicos e pesquisa. IR 780 é caracterizado por sua alta fotostabilidade e baixa toxicidade, que são essenciais para a imagem in vivo. Além disso, foi estudado por seu potencial em sistemas de entrega de medicamentos direcionados devido à sua capacidade de acumular-se seletivamente em certos tipos de células cancerosas. As propriedades únicas do corante permitem que ele sirva como uma ferramenta valiosa tanto na pesquisa fundamental quanto em aplicações clínicas, particularmente nos campos de oncologia e imagem molecular. No geral, IR 780 representa um avanço significativo no desenvolvimento de agentes de imagem que podem melhorar a visualização de processos biológicos em tempo real.
Fórmula:C36H44ClN2·I
InChI:InChI=1S/C36H44ClN2.HI/c1-7-24-38-30-18-11-9-16-28(30)35(3,4)32(38)22-20-26-14-13-15-27(34(26)37)21-23-33-36(5,6)29-17-10-12-19-31(29)39(33)25-8-2;/h9-12,16-23H,7-8,13-15,24-25H2,1-6H3;1H/q+1;/p-1
Chave InChI:InChIKey=IRPKBYJYVJOQHQ-UHFFFAOYSA-M
SMILES:C(CC)N1C=2C(C(C)(C)C1=CC=C3C(Cl)=C(C=CC4=[N+](CCC)C=5C(C4(C)C)=CC=CC5)CCC3)=CC=CC2.[I-]
Sinónimos:- 2-[(Z)-2-{(3E)-2-chloro-3-[(2E)-2-(3,3-dimethyl-1-propyl-1,3-dihydro-2H-indol-2-ylidene)ethylidene]cyclohex-1-en-1-yl}ethenyl]-3,3-dimethyl-1-propyl-3H-indolium iodide
- 3H-Indolium, 2-(2-(2-chloro-3-((1,3-dihydro-3,3-dimethyl-1-propyl-2H-indol-2-ylidene)ethylidene)-1-cyclohexen-1-yl)ethenyl)-3,3-dimethyl-1-propyl-, iodide
- 3H-Indolium, 2-(2-(2-chloro-3-(2-(1,3-dihydro-3,3-dimethyl-1-propyl-2H-indol-2-ylidene)ethylidene)-1-cyclohexen-1-yl)ethenyl)-3,3-dimethyl-1-propyl-, iodide (1:1)
- Ads 775Pi
- Ir 780
- IR 780 iodide
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7 produtos.
IR-780 iodide
CAS:IR-780 iodide is a water-soluble drug that has been shown to have significant cytotoxicity against prostate cancer cells. It binds to the mitochondrial membrane potential, which is involved in energy production and the regulation of the cell cycle. IR-780 iodide is taken up by tumor cells, where it inhibits adriamycin uptake and induces apoptosis. In vitro assays have shown that IR-780 iodide can be used as a diagnostic tool for detecting bladder cancer by binding to the mitochondria of cells from patients with bladder cancer. In vivo studies have been done in mice to determine the effectiveness of IR-780 iodide in treating cervical cancer. These studies showed that IR-780 iodide was not significantly effective in vivo, due to its low bioavailability and lack of specificity for cervical cancer cells. Histological analysis showed that IR-780 iodide did not inhibit tumor growth or induce apoptosis in vivo.Fórmula:C36H44ClIN2Pureza:Min. 95%Peso molecular:667.11 g/mol11-Chloro-1,1?-Di-N-Propyl-3,3,3?,3?-Tetramethyl-10,12-Trimethyleneindatricarbocyanine Iodide
CAS:11-Chloro-1,1?-Di-N-Propyl-3,3,3?,3?-Tetramethyl-10,12-Trimethyleneindatricarbocyanine IodidePureza:98%Peso molecular:667.11g/mol3H-Indolium,2-[2-[2-chloro-3-[(1,3-dihydro-3,3-dimethyl-1-propyl-2H-indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-1-propyl-, iodide
CAS:Fórmula:C36H44ClIN2Pureza:98%Cor e Forma:SolidPeso molecular:667.1054IR-780 Iodide
CAS:IR-780 Iodide: a near-infrared dye for HIF-1α/glycolysis ABCB10-dependent human CSC characterization.Fórmula:C36H44ClIN2Pureza:99.98%Cor e Forma:SolidPeso molecular:667.1211-Chloro-1,1'-di-n-propyl-3,3,3',3'-tetramethyl-10,12-trimethyleneindatricarbocyanine iodide, 95%
CAS:11-Chloro-1,1'-di-n-propyl-3,3,3',3'-tetramethyl-10,12-trimethyleneindatricarbocyanine iodide is used as a laser and IR dye. It is also used as lithographic computer to plate laser applications. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C36H44ClIN2Pureza:95%Cor e Forma:Green/gold to dark green, Crystals or crystalline powderPeso molecular:667.12IR 780
CAS:Fórmula:C36H44ClIN2Pureza:>95.0%(HPLC)(qNMR)Cor e Forma:Yellow to Brown to Dark green powder to crystalPeso molecular:667.12
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