CAS 3810-74-0: Sulfato de estreptomicina
Descrição:
Sulfato de estreptomicina é um antibiótico aminoglicosídeo derivado da bactéria Streptomyces griseus. É utilizado principalmente para tratar várias infecções bacterianas, particularmente aquelas causadas por Mycobacterium tuberculosis, tornando-se significativo na terapia da tuberculose. O composto é caracterizado por sua capacidade de inibir a síntese de proteínas bacterianas ao se ligar à subunidade ribossomal 30S, o que interrompe o processo de tradução. Sulfato de estreptomicina é um pó cristalino branco a ligeiramente amarelo que é solúvel em água, o que facilita sua administração por injeção. Possui uma fórmula molecular que reflete sua estrutura complexa, incluindo múltiplos grupos amino e hidroxila. A forma sulfato melhora sua solubilidade e estabilidade. Efeitos colaterais comuns incluem ototoxicidade e nefrotoxicidade, exigindo monitoramento cuidadoso durante o tratamento. Sulfato de estreptomicina também é notável por seu papel no desenvolvimento de resistência a antibióticos, sublinhando a importância do uso criterioso em ambientes clínicos. No geral, continua sendo um agente crítico no arsenal contra certas infecções bacterianas, particularmente no contexto de cepas multirresistentes.
Fórmula:C21H39N7O12H2O4S
InChI:InChI=1S/C21H39N7O12.H2O4S/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;1-5(2,3)4/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);(H2,1,2,3,4)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;/m0./s1
Chave InChI:InChIKey=CFCMMYICHMLDCC-RMIBZTJPSA-N
SMILES:S(=O)(=O)(O)O.O([C@H]1[C@H](O[C@@H]2[C@@H](NC(=N)N)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]2O)O[C@@H](C)[C@@]1(C=O)O)[C@H]3[C@@H](NC)[C@H](O)[C@@H](O)[C@H](CO)O3
Sinónimos:- 1,1'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (1:1)
- 2,2'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (2:3)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N,N′-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N<sup>1</sup>,N<sup>3</sup>-bis(aminoiminomethyl)-, sulfate (2:3)
- Ag Streptomycin
- Agri-Strep
- Agrimycin 17
- Agrimycin sulfate
- Ambistryn
- Ambistryn S
- D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1→4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
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FOURTH INTERNATIONAL STANDARD FOR STREPTOMYCIN
CAS:FOURTH INTERNATIONAL STANDARD FOR STREPTOMYCINFórmula:C42H84N14O36S3Peso molecular:1457.384Streptomycin Sulphate (STM)
CAS:Fórmula:(C21H39N7O12)2·3H2SO4Cor e Forma:White to off - white, Crystalline powder, Clear, Pale yellowPeso molecular:1457.38Streptomycin Sulfate
CAS:Streptomycins and their derivatives; salts thereof, nesFórmula:(C21H39N7O12)2·3(H2SO4)Cor e Forma:White PowderPeso molecular:1162.53134Streptomycin sulfate
CAS:Streptomycin sulfate (Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor.Fórmula:C21H39N7O12H2SO4Pureza:99.39% - 99.86%Cor e Forma:White To Off-White PowderPeso molecular:728.68Streptomycin sulfate, Cell Culture Reagent
CAS:Inhibits initiation and causes misreading of rRNA in protein synthesis Streptomycin sulfate is used to study the mechanisms of streptomycin resistance. It is used to inhibit bacterial contamination in cell culture applications in association with penicillin. It is an antibiotic drug initially used for tuberculosis treatment. It inhibits protein synthesis by binding to 30S ribosomal subunit, which induces the misreading of the genetic code. It is involved in the initiation of translation of DNA, thereby results in death for a susceptible bacterium. Further, it controls bacterial and fungal diseases of certain fruit, vegetables, seed, ornamental crops and algae in ornamental ponds and aquaria This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C42H84N14O36S3Peso molecular:1457.38Streptomycin sulfate
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C42H84N14O36S3Cor e Forma:White to off-white, PowderPeso molecular:1457.38Streptomycin Sulfate
CAS:Fórmula:C21H39N7O12H2SO4Pureza:>95.0%(T)(N)Cor e Forma:White to Light yellow powder to crystalPeso molecular:728.69Streptomycin sulfate
CAS:Inhibitor of protein synthesis; aminoglycosideFórmula:(C21H39N7O12)2•(H2SO4)3Pureza:Min. 720 Iu/MgCor e Forma:White Off-White PowderPeso molecular:1,457.39 g/molStreptomycin sulfate
CAS:Produto ControladoFórmula:C21H39N7O12H2O4SCor e Forma:NeatPeso molecular:1457.38Streptomycin sulfate salt
CAS:4x25kgFórmula:C21H39N7O12·5H2SO4Pureza:≥ 720IU/mg (dry basis)Cor e Forma:White to off-white powderPeso molecular:728.69Streptomycin Sulfate [for Protein Research]
CAS:Fórmula:C21H39N7O12H2SO4Pureza:>95.0%(N)Cor e Forma:White to Light yellow powder to crystalPeso molecular:728.69Streptomycin Sulfate
CAS:Fórmula:C21H39N7O12H2O4SCor e Forma:White To Off-White SolidPeso molecular:581.58 3/2 98.08Streptomycin sulfate salt, Ph. Eur. grade
CAS:Fórmula:C21H39N7O12·5H2SO4Cor e Forma:White to off-white powderPeso molecular:728.69Streptomycin sulfate, Antibiotic for Culture Media Use Only
CAS:Streptomycin sulfate is an antibiotic that inhibits the growth of bacteria by binding to the ribosomal subunit and interfering with protein synthesis. It is used in culture media for the production of human antibodies as well as in drug therapy for methicillin-resistant staphylococcus. Streptomycin sulfate has a high specific activity and low sensitivity, but it also has a low solubility in water. The active form of streptomycin sulfate is streptomycin A, which is produced by the addition of a phenyl ring to neomycin sulfate. In plant roots, streptomycin sulfate inhibits cyanogenic glycosides from being hydrolyzed into hydrogen cyanide (HCN) and benzaldehyde.Fórmula:C42H84N14O36S3Peso molecular:1,457.40 g/molRef: 3D-S-8500
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