CAS 64-75-5: (-)-Cloridrato de tetraciclina
Descrição:
(-)-Cloridrato de tetraciclina é um antibiótico de amplo espectro pertencente à classe das tetraciclinas, utilizado principalmente para tratar várias infecções bacterianas. É caracterizado por sua complexa estrutura policíclica, que inclui quatro anéis fundidos, contribuindo para sua capacidade de inibir a síntese de proteínas nas bactérias ao se ligar à subunidade ribossomal 30S. Este composto é tipicamente apresentado como um sal de cloridrato, melhorando sua solubilidade em água. (-)-Cloridrato de tetraciclina exibe uma cor amarela a laranja e é sensível à luz, o que pode levar à degradação. É eficaz contra uma ampla gama de bactérias gram-positivas e gram-negativas, bem como alguns protozoários. A substância também é conhecida por suas propriedades anti-inflamatórias e às vezes é usada no tratamento da acne e outras condições de pele. No entanto, seu uso pode levar a efeitos colaterais, incluindo distúrbios gastrointestinais e fotossensibilidade. Devido ao seu potencial de causar descoloração dos dentes em crianças, seu uso geralmente é evitado em mulheres grávidas e crianças pequenas. O armazenamento adequado longe da luz e da umidade é essencial para manter sua estabilidade e eficácia.
Fórmula:C22H24N2O8·ClH
InChI:InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
Chave InChI:InChIKey=XMEVHPAGJVLHIG-FMZCEJRJSA-N
SMILES:O[C@@]12[C@@](C[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H].Cl
Sinónimos:- (2E,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
- (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5aα,6β,12aα)]-
- 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthalenecarboxamide hydrochloride
- 4-(Dimethylamino)-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide Hydrochloride (1:1)
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TETRACYCLINE HYDROCHLORIDE RS
CAS:TETRACYCLINE HYDROCHLORIDE RSFórmula:C22H25ClN2O8Peso molecular:480.8955Tetracycline hydrochloride (10mg/ml)
CAS:Tetracycline hydrochloride (10mg/ml)Cor e Forma:SolutionPeso molecular:494.92g/molTetracycline hydrochloride, Antibiotic for Culture Media Use Only
CAS:Tetracycline hydrochloride is a broad-spectrum antibiotic and is an electron transfer agent. It has been shown to be effective against bacterial infections in humans and has been used in cultures for the prevention of bacterial contamination. As an electron transfer agent, it is used in electron microscopy to study the surface of biological cells. Tetracycline hydrochloride enters bacterial cells by diffusion and interacts with the cytoplasmic membrane, where it induces a redox reaction that leads to cell death. The efficacy of tetracycline hydrochloride in treating candida albicans (yeast) was studied using in-vitro activity and showed that carboxymethyl chitosan nanoparticles were able to enhance the treatment efficiency.Fórmula:C22H25ClN2O8Pureza:Min. 88.0 Area-%Peso molecular:480.90 g/molRef: 3D-T-1961
1kgA consultar5kgA consultar10kgA consultar25kgA consultar2500gA consultar-Unit-kgkgA consultarTetracycline hydrochloride, USP grade
CAS:Fórmula:C22H24N2O8·HClCor e Forma:Yellow powderPeso molecular:480.91Tetracycline Hydrochloride
CAS:Tetracyclines and their derivatives; salts thereofFórmula:C22H24N2O8·ClHCor e Forma:Yellow PowderPeso molecular:480.12994Tetracycline Hydrochloride (TC), 95%
CAS:Fórmula:C22H24N2O8·HClPureza:min. 95%Cor e Forma:Yellow, Crystalline powderPeso molecular:480.90Tetracycline hydrochloride
CAS:Produto ControladoFórmula:C22H24N2O8·ClHCor e Forma:NeatPeso molecular:480.90Tetracycline hydrochloride
CAS:Fórmula:C22H24N2O8·HClPureza:≥ 95.0%Cor e Forma:Yellow powderPeso molecular:480.91Tetracycline Hydrochloride
CAS:Applications Antibiotic substance produced by Streptomyces spp. Antiamebic; antibacterial; antirickettsial. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Weiss, et al.: Antibiot. Chemother., 7, 374 (1957), Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971),Fórmula:C22H24N2O8·ClHCor e Forma:NeatPeso molecular:480.90Tetracycline Hydrochloride
CAS:Fórmula:C22H24N2O8·HClPureza:>98.0%(T)Cor e Forma:Light yellow to Amber to Dark green powder to crystalPeso molecular:480.90Tetracycline hydrochloride
CAS:Antibiotic of tetracycline class; protein synthesis inhibitorFórmula:C22H25ClN2O8Cor e Forma:Yellow PowderPeso molecular:480.9 g/molTetracycline HCl (Oxytetracycline EP Impurity B HCl)
CAS:Fórmula:C22H24N2O8·HClCor e Forma:Pale Yellow SolidPeso molecular:444.45 36.46Tetracycline hydrochloride - USP
CAS:Tetracycline hydrochloride - USP is a broad-spectrum antibiotic, which is a synthetic derivative of chlortetracycline produced from the bacterium *Streptomyces aureofaciens*. It functions by inhibiting protein synthesis in bacteria, specifically binding to the 30S ribosomal subunit. This action prevents the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, thereby halting bacterial growth and replication. Tetracycline hydrochloride is primarily used in the treatment of various infections caused by susceptible strains of gram-positive and gram-negative bacteria, including respiratory tract infections, skin infections, and certain sexually transmitted diseases. Its broad-spectrum efficacy makes it a versatile agent for managing bacterial infections in both human and veterinary medicine. Additionally, it is utilized in research settings for studying bacterial protein synthesis and antibiotic resistance patterns.Fórmula:C22H25ClN2O8Cor e Forma:Yellow PowderPeso molecular:480.9 g/mol
