
CAS 74011-58-8: Enoxacina
Descrição:
Enoxacina é um antibiótico sintético pertencente à classe das fluoroquinolonas, utilizado principalmente para tratar infecções bacterianas. Sua estrutura química apresenta um núcleo bicíclico que inclui um moiety de quinolona, essencial para sua atividade antibacteriana. Enoxacina exibe atividade de amplo espectro contra várias bactérias Gram-negativas e algumas Gram-positivas, inibindo a girase do DNA bacteriano e a topoisomerase IV, enzimas cruciais para a replicação e transcrição do DNA. A substância é tipicamente administrada por via oral e é bem absorvida no trato gastrointestinal. Enoxacina é conhecido por seu perfil de toxicidade relativamente baixo, embora possa causar efeitos colaterais como distúrbios gastrointestinais, efeitos no sistema nervoso central e possível dano nos tendões. É importante notar que o uso de fluoroquinolonas, incluindo Enoxacina, tem sido associado a um aumento do risco de efeitos colaterais graves, levando a práticas de prescrição mais cautelosas. Assim como com todos os antibióticos, o uso apropriado é crítico para prevenir o desenvolvimento de resistência a antibióticos.
Fórmula:C15H17FN4O3
InChI:InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23)
Chave InChI:InChIKey=IDYZIJYBMGIQMJ-UHFFFAOYSA-N
SMILES:C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(N2)N3CCNCC3
Sinónimos:- 1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-
- 1-Ethyl-6-Fluoro-4-Oxo-7-(Piperazin-1-Yl)-1,4-Dihydro-1,8-Naphthyridine-3-Carboxylic Acid
- 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic Acid
- 1-Ethyl-6-fluoro-4-oxo-7-piperazin-4-ium-1-yl-1,8-naphthyridine-3-carboxylate
- At 2266
- Ci 919
- Enofloxacin
- Enofloxacine
- Enoksetin
- Enoxacin (Patent-No-Supply)
- Enoxacine
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14 produtos.
Enoxacin
CAS:Enoxacin is a nonsteroidal anti-inflammatory drug that inhibits the production of prostaglandins and thromboxanes. It has been shown to be effective against infectious diseases caused by bacteria, protozoa, and fungi, including E. coli, Salmonella typhimurium, Giardia lamblia, Candida albicans, Trichophyton mentagrophytes, Microsporum canis and T. violaceum. Enoxacin's mechanism of action is not fully understood but it may inhibit the transcription of genes that code for proteins involved in inflammation or produce an inhibitory response element in the promoter region of these genes. This drug also has minimal toxicity to humans and low levels of drug interactions with other drugs when taken concurrently. Nitrite ion and human polymorphonuclear leukocytes (PMNL) are both important factors in enoxacin's mechanism of action as they activate the enzyme guanylate cyclase whichFórmula:C15H17FN4O3Pureza:Min. 95%Peso molecular:320.32 g/mol1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
CAS:Pureza:99.0%Cor e Forma:SolidPeso molecular:320.3240051269531Enoxacin Sesquihydrate
CAS:Fórmula:C15H17FN4O3H2OPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:347.34Enoxacin
CAS:Applications A fluororquinolone antibacterial used to treat urinary tract infections and gonorrhea. References Liu, A., et al.: Antimicrob. Agents Chemother., 54, 1393 (2010), Chen, P., et al.: Drug Test Anal., 2, 24 (2010), Gohil, V., et al.: Nat., Biotechnol., 28, 249 (2010),Fórmula:C15H17FN4O3Cor e Forma:NeatPeso molecular:320.32Enoxacin
CAS:Fórmula:C15H17FN4O3·xH2OPureza:≥ 98.0% (dried basis)Cor e Forma:White to yellow crystalline powderPeso molecular:320.32 (anhydrous)Enoxacin
CAS:Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.Fórmula:C15H17FN4O3Pureza:98.68% - 99.89%Cor e Forma:Off-White To Yellow CrystalsPeso molecular:320.32Enoxacin
CAS:Enoxacin is an antibacterial agent used in the treatment of gastro enteritis including infectious diarrhea, respiratory tract infections, gonorrhea and urinary tract infections. It is a bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C15H17FN4O3Cor e Forma:Powder or crystals or crystalline powderPeso molecular:320.321-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid
CAS:1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acidPureza:98%Peso molecular:320.32g/molSmart Solutions™ v59 PharmaVetResiMix Kit 1
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Cor e Forma:Mixture