CAS: 80213-01-0

(4-hydroxypiperidin-1-yl)(phenyl)methanone is a synthon that can be used as a building block for the synthesis of amines. It has been observed to inhibit glycosidase activity, which causes it to have potential anti-HIV activity. This synthon is not only active against trypanosomiasis but also has been shown to have antimicrobial and antifungal properties. Its chloride salt form is soluble in water, making it a good candidate for use in organic synthesis. The synthesis of (4-hydroxypiperidin-1-yl)(phenyl)methanone is achieved by reacting piperidine with chloroformate in the presence of an acid catalyst.

N-Benzoyl-4-hydroxypiperidine