Syk
Os inibidores da Syk (tirosina quinase do baço) são compostos que têm como alvo a Syk, uma quinase envolvida na sinalização das células imunes e na regulação da angiogênese. A Syk desempenha um papel nas respostas inflamatórias que podem contribuir para a angiogênese tumoral. Inibir a Syk pode reduzir a formação de vasos sanguíneos induzida por inflamação em tumores, tornando esses inibidores valiosos na terapia contra o câncer e na pesquisa sobre inflamação. Na CymitQuimica, oferecemos uma ampla gama de inibidores de Syk de alta qualidade para apoiar sua pesquisa em imunologia, oncologia e angiogênese.
Produtos da "Syk"
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Entospletinib
CAS:Entospletinib (GS-9973) (IC50= 7.7 nM)is a specific Syk inhibitor, which is orally bioavailable.Fórmula:C23H21N7OPureza:98.2% - 99.51%Cor e Forma:SolidPeso molecular:411.46Ref: TM-T6101
1mg38,00€2mg49,00€5mg81,00€10mg97,00€25mg170,00€50mg259,00€100mg416,00€200mg617,00€1mL*10mM (DMSO)88,00€Syk-IN-8
CAS:Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells.Fórmula:C23H26N10Pureza:98%Cor e Forma:SolidPeso molecular:442.52Gusacitinib
CAS:Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).Fórmula:C24H28N8O2Pureza:98.06% - 99.94%Cor e Forma:SolidPeso molecular:460.53Ref: TM-T14331
1mg42,00€5mg88,00€10mg123,00€25mg188,00€50mg350,00€100mg522,00€200mg750,00€1mL*10mM (DMSO)116,00€R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Fórmula:C16H13FN4O2Pureza:99.06% - 99.84%Cor e Forma:SolidPeso molecular:312.3Ref: TM-T3185
1mg39,00€2mg51,00€5mg84,00€10mg124,00€25mg219,00€50mg329,00€100mg487,00€500mg1.026,00€1mL*10mM (DMSO)92,00€Lanraplenib succinate
CAS:Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Fórmula:C58H68N18O14Cor e Forma:SolidPeso molecular:1241.294Lanraplenib monosuccinate
CAS:Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.Fórmula:C27H31N9O5Pureza:98%Cor e Forma:SolidPeso molecular:561.59Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Fórmula:C9H11NO3·HClPureza:99.94%Cor e Forma:SolidPeso molecular:217.65TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Fórmula:C17H22ClFN6OPureza:99.28% - 99.82%Cor e Forma:SolidPeso molecular:380.85BAY 61-3606 dihydrochloride
CAS:BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Fórmula:C20H18N6O3·2HClPureza:99.46%Cor e Forma:SolidPeso molecular:463.32Ref: TM-T6776
1mg38,00€5mg84,00€10mg116,00€25mg187,00€50mg279,00€100mg406,00€200mg565,00€1mL*10mM (DMSO)87,00€PRT062607 hydrochloride
CAS:PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Fórmula:C19H23N9O·HClPureza:97.11% - 99.93%Cor e Forma:SolidPeso molecular:429.91Ref: TM-T2696
1mg60,00€2mg86,00€5mg127,00€10mg187,00€25mg326,00€50mg500,00€200mg948,00€1mL*10mM (DMSO)139,00€ER-27319
CAS:ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosineFórmula:C20H22N2O5Pureza:98%Cor e Forma:SolidPeso molecular:370.4Sovleplenib
CAS:Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors & ITP studies.Fórmula:C24H30N6O3SPureza:98.51%Cor e Forma:SolidPeso molecular:482.6Ref: TM-T32088
1mg127,00€5mg305,00€10mg459,00€25mg777,00€50mg1.216,00€100mg1.890,00€200mg2.547,00€1mL*10mM (DMSO)324,00€R406
CAS:R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.Fórmula:C22H23FN6O5·C6H6O3SPureza:97.67% - 98.82%Cor e Forma:SolidPeso molecular:628.63Ref: TM-T6174
1mg48,00€2mg60,00€5mg94,00€10mg150,00€25mg316,00€50mg470,00€100mg683,00€1mL*10mM (DMSO)127,00€Syk-IN-3
CAS:Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.Fórmula:C24H28N4O3SPureza:100% - 97.99%Cor e Forma:SolidPeso molecular:452.57MNS
CAS:Fórmula:C9H7NO4Pureza:>98.0%(GC)Cor e Forma:Light yellow to Yellow to Green powder to crystalPeso molecular:193.16
