IAP
Os inibidores das proteínas inibidoras da apoptose (IAP) são compostos que bloqueiam a atividade das IAPs, uma família de proteínas que previnem a apoptose, inibindo caspases e outros componentes da maquinaria apoptótica. Os inibidores de IAP promovem a apoptose em células cancerígenas ao neutralizar esses sinais de sobrevivência, tornando-os ferramentas importantes na pesquisa e terapia contra o câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de IAP de alta qualidade para apoiar sua pesquisa em oncologia, apoptose e desenvolvimento terapêutico.
Produtos da "IAP"
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AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Fórmula:C60H82N8O10Pureza:97.76%Cor e Forma:SolidPeso molecular:1075.36CD47 Protein, Mouse, Recombinant (His)
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:SDS-PAGE: 98.3%; SEC-HPLC: 98.5%Cor e Forma:Lyophilized PowderPeso molecular:15.3 kDa (predicted); 34-44 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (mFc)
CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag.Cor e Forma:Lyophilized PowderPeso molecular:48-65 KDa (reducing condition)Anti-CD47 Antibody-PE (9X161)
Anti-CD47 Antibody-PE (9X161) is a PE-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-PE (9X161) can be used in FCM.Cor e Forma:Odour LiquidCUDC-427
CAS:CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.Fórmula:C29H36N6O4SPureza:98.99%Cor e Forma:SolidPeso molecular:564.7CD47 Protein, Human, Recombinant (hFc)
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:40.7 kDa (predicted); 48-60 kDa (reducing condition, due to glycosylation)AZD5582
CAS:AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.Fórmula:C58H78N8O8Pureza:98.75%Cor e Forma:SolidPeso molecular:1015.29CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Cor e Forma:Lyophilized PowderPeso molecular:17.1 kDa (predicted); 38.8 kDa (reducing conditions)GDC-0152
CAS:GDC-0152 is a potent inhibitor of IAPs.Fórmula:C25H34N6O3SPureza:97.18% - 99.32%Cor e Forma:SolidPeso molecular:498.64BV6
CAS:BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.Fórmula:C70H96N10O8Pureza:97.46% - 99.89%Cor e Forma:SolidPeso molecular:1205.57Ref: TM-T6428
1mg52,00€2mg67,00€5mg95,00€10mg153,00€25mg301,00€50mg567,00€100mg810,00€1mL*10mM (DMSO)188,00€ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Fórmula:C30H42FN5O3Pureza:97.81% - 98.33%Cor e Forma:SolidPeso molecular:539.68Ref: TM-TQ0029
1mg84,00€5mg144,00€10mg216,00€25mg432,00€50mg638,00€100mg908,00€1mL*10mM (DMSO)172,00€CD47 Protein, Mouse, Recombinant
CD47 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.8 kDa and the accession number is E5Q371.Cor e Forma:Lyophilized PowderPeso molecular:13.8 kDa (predicted)Anti-CD47 Antibody (8A121)
Anti-CD47 Antibody (8A121) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (8A121) can be used in ELISA.Cor e Forma:Odour LiquidAnti-CD47 Antibody (6T428)
Anti-CD47 Antibody (6T428) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (6T428) can be used in ELISA.Cor e Forma:Odour LiquidSM-164
CAS:SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.Fórmula:C62H84N14O6Pureza:97.25% - 99.92%Cor e Forma:SolidPeso molecular:1121.42Anticancer agent 128
CAS:Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19Fórmula:C26H38N4O4Pureza:98%Cor e Forma:SolidPeso molecular:470.6LCL161
CAS:LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Fórmula:C26H33FN4O3SPureza:99.13% - 99.72%Cor e Forma:SolidPeso molecular:500.63SM-164 Hydrochloride (957135-43-2 free base)
SM-164 Hydrochloride: cell-permeable, binds to XIAP (BIR2/3 domains), IC50 of 1.39 nM, potent XIAP antagonist.Fórmula:C62H85ClN14O6Pureza:98%Cor e Forma:SolidPeso molecular:1157.88Anti-CD47 Antibody (5R542)
Anti-CD47 Antibody (5R542) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5R542) can be used in ELISA.Cor e Forma:Odour LiquidXevinapant
CAS:Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.Fórmula:C32H43N5O4Pureza:98% - 99.48%Cor e Forma:SolidPeso molecular:561.71Ref: TM-T6763
1mg43,00€2mg57,00€5mg93,00€10mg131,00€25mg279,00€50mg525,00€100mg745,00€200mg1.008,00€500mg1.320,00€1mL*10mM (DMSO)145,00€
