Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase
- CDK
- Ciclo celular/Parada
- Chk
- c-Myc
- Dinamina
- DYRK
- Ferroptose
- HSP
- Integrinas
- Cinesina
- KSP
- LIM Quinase
- Microtúbulo associado
- PKC
- PLK
- Rho
- ROCK
- Wee1
Exibir 11 mais subcategorias
Produtos da "Ciclo celular/Ponto de verificação"
Ordenar por
Indatuximab
Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.Cor e Forma:LiquidPeso molecular:145.5 kDaHPH-15
CAS:HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.Fórmula:C19H31N3S4Cor e Forma:SolidPeso molecular:429.735-Fluorouridine
CAS:5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine.Fórmula:C9H11FN2O6Pureza:99.53% - 99.76%Cor e Forma:White PowderPeso molecular:262.19ML264
CAS:ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.Fórmula:C17H21ClN2O4SPureza:99.33% - 99.45%Cor e Forma:SolidPeso molecular:384.88CDK2-IN-30
CAS:CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 of ≤20 nM, utilized primarily in tumor research.Fórmula:C18H25N7O3SCor e Forma:SolidPeso molecular:419.502-Fluoroadenine
CAS:2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.Fórmula:C5H4FN5Pureza:99.49%Cor e Forma:White To Light Yellow Crystal PowderPeso molecular:153.12BS194
CAS:BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.Fórmula:C20H27N5O3Pureza:99.85%Cor e Forma:SolidPeso molecular:385.463,4-Dihydroxybenzylamine hydrobromide
CAS:3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Fórmula:C7H10BrNO2Pureza:97.28%Cor e Forma:Light Beige Crystalline PowderPeso molecular:220.06BMS-688521
CAS:BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Fórmula:C26H19Cl2N5O4Pureza:98.87%Cor e Forma:SolidPeso molecular:536.37Ref: TM-T14676
1mg183,00€5mg464,00€10mg655,00€25mg1.169,00€50mg1.539,00€100mg1.882,00€1mL*10mM (DMSO)547,00€LY3405105
CAS:LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-Fórmula:C26H39N7O3Pureza:98.01%Cor e Forma:SolidPeso molecular:497.63IMT1
CAS:IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Fórmula:C21H21NO4Pureza:98.07% - 98.14%Cor e Forma:SolidPeso molecular:351.4Ref: TM-T8841
1mg81,00€5mg170,00€10mg301,00€25mg563,00€50mg805,00€100mg1.111,00€1mL*10mM (DMSO)188,00€PHI-101
CAS:PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.Fórmula:C19H19FN4O2SPureza:99.40%Cor e Forma:SolidPeso molecular:386.44Ref: TM-T81490
1mg173,00€5mg437,00€10mg702,00€25mg1.406,00€50mg2.262,00€100mg3.600,00€1mL*10mM (DMSO)469,00€SEL120-34A HCl
CAS:SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectivelyFórmula:C15H19Br2ClN4Pureza:98.13% - 99.75%Cor e Forma:SolidPeso molecular:450.6(S)-GNA-T-phosphoramidite
CAS:(S)-GNA-T-phosphoramidite is a nucleoside analog commonly used in the synthesis of other active compounds.Fórmula:C38H47N4O7PPureza:99.35%Cor e Forma:SolidPeso molecular:702.78AZD-5438
CAS:AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).Fórmula:C18H21N5O2SPureza:99.73% - 99.87%Cor e Forma:SolidPeso molecular:371.46BUR1
CAS:BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Fórmula:C16H17N5Pureza:90%Cor e Forma:SolidPeso molecular:279.34Obtustatin triacetate
Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of theFórmula:C184H284N52O57S8·3C2H4O2Pureza:99.51%Cor e Forma:SolidPeso molecular:4573.21MYC-RIBOTAC
MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tetheredFórmula:C55H58N10O11SPureza:98%Cor e Forma:SolidPeso molecular:1067.17Lerociclib dihydrochloride
CAS:Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/Fórmula:C26H36Cl2N8OPureza:97.40%Cor e Forma:SolidPeso molecular:547.52CCT241533 hydrochloride
CAS:CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).Fórmula:C23H28ClFN4O4Pureza:97.13%Cor e Forma:SolidPeso molecular:478.95Ref: TM-T10718L
1mg73,00€2mg96,00€5mg159,00€10mg240,00€25mg515,00€50mg852,00€100mg1.264,00€500mg2.547,00€1mL*10mM (DMSO)170,00€DMT-dU-CE Phosphoramidite
CAS:DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.Fórmula:C39H47N4O8PPureza:97.58%Cor e Forma:SolidPeso molecular:730.79BMS-1001
CAS:BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).Fórmula:C35H34N2O7Pureza:98.43%Cor e Forma:SolidPeso molecular:594.7Abciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Pureza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Cor e Forma:LiquidPeso molecular:95.18 kDaVotoplam HCl
CAS:Votoplam HCl is a systemically acting gene splicing regulator that down-regulates the levels of huntingtin protein, which to inhibit Huntington's disease (HD).Fórmula:C21H26ClN9OPureza:99.49%Cor e Forma:SoildPeso molecular:455.94
