Dinamina
Os inibidores de dinamina têm como alvo a dinamina, uma enzima GTPase que desempenha um papel crucial na endocitose, no tráfego de vesículas e na citocinese. A dinamina está envolvida na cisão de vesículas a partir de membranas e é essencial para a distribuição adequada dos componentes celulares durante a divisão celular. Inibir a dinamina pode interromper esses processos, levando a defeitos na divisão celular e induzindo a parada do ciclo celular. Os inibidores de dinamina são valiosos no estudo da endocitose, divisão celular e dinâmica de membranas. Na CymitQuimica, oferecemos uma gama de inibidores de dinamina de alta qualidade para apoiar sua pesquisa em biologia celular, tráfego de membranas e regulação do ciclo celular.
Produtos da "Dinamina"
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13 produtos desta categoria.
Dynamin IN-2
CAS:Dynamin IN-2 (compound 43) is a Wiskostatin analogue.Fórmula:C22H21ClN2OPureza:98.81% - 98.83%Cor e Forma:SoildPeso molecular:364.87Ref: TM-T64369
1mg140,00€5mg331,00€10mg439,00€25mg667,00€50mg894,00€100mg1.198,00€200mg1.596,00€1mL*10mM (DMSO)341,00€DNM1 Protein, Human, Recombinant (His)
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.Cor e Forma:Lyophilized PowderPeso molecular:32.2 kDa (predicted)Mdivi-1
CAS:Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).Fórmula:C15H10Cl2N2O2SPureza:96.57% - 99.6%Cor e Forma:SolidPeso molecular:353.22Ref: TM-T1907
5mg47,00€10mg56,00€25mg90,00€50mg153,00€100mg227,00€200mg338,00€500mg558,00€1mL*10mM (DMSO)50,00€POSH-IN-2
CAS:POSH-IN-2 (MIDI) is a mitochondrial fission inhibitor and a DRP1 inhibitor that effectively prevents mitochondrial fragmentation caused by cellular stress and genetic mitochondrial damage. It covalently interacts with DRP1-C367 to target the interaction of DRP1 with multiple receptors.Fórmula:C22H16N2O2Cor e Forma:SolidPeso molecular:340.37Dynapyrazole A
CAS:Dynapyrazole A inhibits dynein 1 and 2 (IC50s: 2.3, 2.6 μM) and Hedgehog signaling (IC50: 1.9 μM).Fórmula:C20H12ClIN4OPureza:98.01%Cor e Forma:SolidPeso molecular:486.69Trimethyloctadecylammonium bromide
CAS:Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.Fórmula:C21H46N·BrPureza:99.09%Cor e Forma:Solid SolidPeso molecular:392.5Tetradecyltrimethylammonium bromide
CAS:Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.Fórmula:C17H38BrNPureza:100%Cor e Forma:SolidPeso molecular:336.39Schaftoside
CAS:Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.Fórmula:C26H28O14Pureza:100% - 99.32%Cor e Forma:SolidPeso molecular:564.49Ref: TM-T3898
1mg42,00€5mg85,00€10mg111,00€25mg210,00€50mg311,00€100mg467,00€200mg653,00€1mL*10mM (DMSO)95,00€Hydroxy-Dynasore
CAS:Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,Fórmula:C18H14N2O5Pureza:100% - 97.60%Cor e Forma:SolidPeso molecular:338.31Ref: TM-T6822
5mg50,00€10mg84,00€25mg137,00€50mg221,00€100mg329,00€200mg490,00€500mg783,00€1mL*10mM (DMSO)55,00€Dynole 34-2
CAS:Dynole 34-2 is a non-competitive inhibitor of dynamin1 and dynamin2 GTPases that inhibits receptor-mediated endocytosis and synaptic vesicle endocytosis.Fórmula:C25H36N4OPureza:99.61%Cor e Forma:SolidPeso molecular:408.58Dynasore
CAS:Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.Fórmula:C18H14N2O4Pureza:95.85% - 99.22%Cor e Forma:SolidPeso molecular:322.31Ref: TM-T1848
5mg49,00€10mg79,00€25mg140,00€50mg259,00€100mg374,00€200mg560,00€500mg883,00€1mL*10mM (DMSO)87,00€Drp1 peptide inhibitor P110
CAS:Compound P110 (Drp1 peptide inhibitor P110) is a selective Drp1 peptide inhibitor with neuroprotective effects. It inhibits the activation of Drp1, prevents Drp1 mitochondrial translocation induced by MPTP, and alleviates dopamine neuron loss, dopaminergic terminal damage, and behavioral deficits caused by MPTP. This compound is useful for Alzheimer's disease research. Additionally, Compound P110 reduces mitochondrial and organ damage in animal models of Huntington's disease, cerebral ischemia, and myocardial infarction.Fórmula:C100H179N45O25Cor e Forma:SolidPeso molecular:2411.78IIQLPEIVVV TFA
IIQLPEIVVV TFA serves as a specific inhibitor targeting the Drp1-Mff interaction. This compound discriminates between physiological and pathological fission, hindering physiological fission which leads to mitochondrial dysfunction. IIQLPEIVVV TFA is also utilized in research related to Huntington's disease.Fórmula:C54H95N11O14·xC2HF3O2Cor e Forma:SolidPeso molecular:1122.40 (free base)
