Transcriptase reversa
Os inibidores da transcriptase reversa têm como alvo a enzima transcriptase reversa, que é responsável por converter o RNA viral em DNA em retrovírus, incluindo o HIV. Esses inibidores são a base da terapia antirretroviral, impedindo a replicação do vírus nas células hospedeiras. Inibidores da transcriptase reversa também são usados em pesquisas para estudar a replicação viral e o desenvolvimento de novas terapias antivirais. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores da transcriptase reversa de alta qualidade para apoiar sua pesquisa em virologia, desenvolvimento de medicamentos antivirais e biologia molecular.
Produtos da "Transcriptase reversa"
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47 produtos desta categoria.
MK-6186
CAS:MK-6186 is a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity for the study of viral infections.Fórmula:C21H12Cl2N6OPureza:97.03%Cor e Forma:SolidPeso molecular:435.27Efavirenz
CAS:Efavirenz (DMP 266) is an HIV-1 inhibitor, affecting reverse transcriptase and various cytochrome P450 enzymes.Fórmula:C14H9ClF3NO2Pureza:99.2% - 99.83%Cor e Forma:White To Slightly Pink Crystalline PowderPeso molecular:315.67Ref: TM-T2393
1g404,00€5mg42,00€10mg52,00€25mg71,00€50mg89,00€100mg116,00€500mg273,00€1mL*10mM (DMSO)49,00€Didanosine
CAS:Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).Fórmula:C10H12N4O3Pureza:99.64%Cor e Forma:White Crystalline PowderPeso molecular:236.23Tenofovir Disoproxil Fumarate
CAS:Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) is a pro-drug, a nucleoside reverse transcriptase inhibitor analog of adenosine.Fórmula:C19H30N5O10P·C4H4O4Pureza:98.60% - 99.02%Cor e Forma:White To Pink CrystallinePeso molecular:635.51Ref: TM-T2409L
10mg50,00€25mg74,00€50mg90,00€100mg124,00€200mg168,00€500mg240,00€1mL*10mM (DMSO)55,00€Suramin Sodium Salt
CAS:Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.Fórmula:C51H34N6Na6O23S6Pureza:97.47% - 99.97%Cor e Forma:WhitePeso molecular:1429.15Abacavir sulfate
CAS:Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activityFórmula:C14H18N6OH2O4SPureza:100% - 99.85%Cor e Forma:White To Off-White SolidPeso molecular:335.38Ref: TM-T6367
10mg47,00€25mg70,00€50mg97,00€100mg136,00€200mg183,00€500mg306,00€1mL*10mM (DMSO)48,00€RO-0335
CAS:RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor.Fórmula:C21H13BrCl2FN3O4SPureza:99.53%Cor e Forma:SolidPeso molecular:573.22Ref: TM-T9223
1mg56,00€5mg119,00€10mg188,00€25mg432,00€50mg638,00€100mg908,00€500mg1.825,00€1mL*10mM (DMSO)131,00€Tenofovir alafenamide hemifumarate
CAS:Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir.Fórmula:C21H29N6O5PC4H4O4Pureza:99.33% - 99.96%Cor e Forma:SolidPeso molecular:534.51EFdA-TP 3TEA
CAS:EFdA-TP 3TEA is a novel, potent, and selective nucleoside reverse transcriptase (RT) inhibitor that inhibits HIV-1 reverse transcriptase by multiple mechanisms.Fórmula:C30H60FN8O12P3Pureza:97.22%Cor e Forma:SoildPeso molecular:836.76HIV-1 inhibitor-6
CAS:HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicingFórmula:C14H10N4O4SPureza:98.49%Cor e Forma:SolidPeso molecular:330.32Stavudine
CAS:Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.Fórmula:C10H12N2O4Pureza:100% - 99.74%Cor e Forma:White PowderPeso molecular:224.21R-10015
CAS:R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.Fórmula:C20H19ClN6O2Pureza:98.68%Cor e Forma:SolidPeso molecular:410.86Ref: TM-T12609
1mg75,00€5mg170,00€10mg256,00€25mg423,00€50mg562,00€100mg792,00€200mg1.074,00€1mL*10mM (DMSO)182,00€Tenofovir Disoproxil
CAS:Tenofovir Disoproxil (GS 4331) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.Fórmula:C19H30N5O10PPureza:99.17%Cor e Forma:SolidPeso molecular:519.44Corilagin
CAS:Corilagin has anti-inflammatory activity.Fórmula:C27H22O18Pureza:99.54% - ≥98%Cor e Forma:Off-White SolidPeso molecular:634.45Dexelvucitabine
CAS:Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Fórmula:C9H10FN3O3Pureza:98.25%Cor e Forma:SolidPeso molecular:227.19BF738735
CAS:BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM).Fórmula:C21H19FN4O3SPureza:90%Cor e Forma:SolidPeso molecular:426.46NNRT-IN-6
NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.Fórmula:C32H31N9O3SCor e Forma:SolidPeso molecular:621.71AG 555
CAS:AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.Fórmula:C19H18N2O3Pureza:100% - 99.51%Cor e Forma:SolidPeso molecular:322.36Zalcitabine
CAS:Zalcitabine (ddC) is a nucleoside analog inhibiting HIV by blocking reverse transcriptase and halting viral DNA synthesis.Fórmula:C9H13N3O3Pureza:99.73% - ≥95%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:211.22Pyridoxal phosphate
CAS:Pyridoxal phosphate, active Vitamin B6, is crucial for amino acid synthesis and neurotransmitter metabolism; it's also a dietary supplement.Fórmula:C8H10NO6PPureza:99.18%Cor e Forma:SolidPeso molecular:247.14Hypericin
CAS:Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.Fórmula:C30H16O8Pureza:99.05% - ≥98%Cor e Forma:Red-Coloured Anthraquinone-DerivativePeso molecular:504.44Ref: TM-T6S0923
1mg57,00€5mg127,00€10mg182,00€25mg360,00€50mg532,00€100mg743,00€500mg1.510,00€1mL*10mM (DMSO)140,00€Lersivirine
CAS:Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.Fórmula:C17H18N4O2Pureza:98.01%Cor e Forma:SolidPeso molecular:310.35Ref: TM-T7700
2mg40,00€5mg60,00€10mg87,00€25mg167,00€50mg255,00€100mg368,00€200mg522,00€1mL*10mM (DMSO)65,00€EFdA-TP tetrasodium
CAS:EFdA-TP tetrasodium is a potent HIV-1 inhibitor that blocks DNA synthesis as an ICT or DCT.Fórmula:C12H11FN5Na4O12P3Pureza:98%Cor e Forma:SolidPeso molecular:621.12Etravirine
CAS:Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.Fórmula:C20H15BrN6OPureza:97.61% - 99.74%Cor e Forma:White To Off-White SolidPeso molecular:435.28Ref: TM-T2551
1g898,00€2mg49,00€5mg74,00€10mg111,00€25mg188,00€50mg279,00€100mg383,00€200mg485,00€1mL*10mM (DMSO)93,00€Abacavir
CAS:Abacavir (Ziagen) is a nucleoside reverse transcriptase inhibitor analog of guanosine.Fórmula:C14H18N6OPureza:99.36% - 99.81%Cor e Forma:White PowderPeso molecular:286.33Ref: TM-T1267
1g344,00€5mg35,00€10mg51,00€25mg77,00€50mg90,00€100mg115,00€200mg144,00€500mg234,00€1mL*10mM (DMSO)50,00€Alizarin Complexone
CAS:Alizarin Complexone (Alizarin-3-methyliminodiacetic acid) is an inhibitor of Rous-associated virus 2 reverse transcriptase.Fórmula:C19H15NO8Pureza:98.78%Cor e Forma:Red To Brown PowderPeso molecular:385.32Islatravir
CAS:Islatravir (MK-8591) is an effective anti-HIV-1 agent.Fórmula:C12H12FN5O3Pureza:98.77%Cor e Forma:SolidPeso molecular:293.25Ref: TM-T16098
1mg80,00€5mg170,00€10mg259,00€25mg454,00€50mg615,00€100mg827,00€200mg1.111,00€1mL*10mM (DMSO)182,00€2,2'-Anhydrouridine
CAS:2,2'-Anhydrouridine (2,2'-Cyclouridine) is a research tool for antiviral and anticancer studies.Fórmula:C9H10N2O5Pureza:98.45%Cor e Forma:SolidPeso molecular:226.193'-Azido-3'-deoxy-5-methylcytidine
CAS:3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase(EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-relatedFórmula:C10H14N6O4Pureza:99.86%Cor e Forma:SolidPeso molecular:282.26Tenofovir
CAS:Tenofovir (GS 1278) is an adenine analog REVERSE TRANSC-RIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B.Fórmula:C9H14N5O4PPureza:98.69% - 99.92%Cor e Forma:White To Tan Solid Solid PowderPeso molecular:287.21Gramine
CAS:Gramine (Donaxine), a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 andFórmula:C11H14N2Pureza:97.23% - 98.14%Cor e Forma:White Crystalline PowderPeso molecular:174.24Dapivirine
CAS:Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.Fórmula:C20H19N5Pureza:98% - 99.77%Cor e Forma:SolidPeso molecular:329.4Doravirine
CAS:Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.Fórmula:C17H11ClF3N5O3Pureza:99.65% - 99.79%Cor e Forma:SolidPeso molecular:425.75Ref: TM-T3632
1mg49,00€2mg69,00€5mg97,00€10mg170,00€25mg335,00€50mg520,00€100mg750,00€500mg1.549,00€1mL*10mM (DMSO)131,00€Azvudine
CAS:Azvudine (FNC) is a powerful NRTI effective against HIV, HBV, HCV, and resistant strains.Fórmula:C9H11FN6O4Pureza:100% - 99.42%Cor e Forma:SolidPeso molecular:286.22Ref: TM-T14489
1mg63,00€5mg136,00€10mg216,00€25mg425,00€50mg645,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)129,00€Lamivudine
CAS:Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring.Fórmula:C8H11N3O3SPureza:100% - 99.56%Cor e Forma:White Crystalline PowderPeso molecular:229.26Adefovir dipivoxil
CAS:Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity againstFórmula:C20H32N5O8PPureza:100% - 98%Cor e Forma:It Has Broad-Spectrum Antiviral ActivityPeso molecular:501.47HIV-1 inhibitor-75
HIV-1inhibitor-75 is a human immunodeficiency virus 1 (HIV-1) inhibitor with an EC50 range of 0.0039-0.338 μM. Its target is the reverse transcriptase, exhibiting an IC50 value of 0.055 μM. Additionally, HIV-1inhibitor-75 demonstrates good metabolic stability in vitro, presenting moderate clearance rates and an extended half-life in human plasma and liver microsomes.Fórmula:C25H20ClN3O3SCor e Forma:SolidPeso molecular:477.96Emtricitabine
CAS:Emtricitabine is a nucleoside reverse transcriptase inhibitor with anti-human immunodeficiency virus (HIV) and hepatitis B virus activity.Cost-effective and quality-assured.Fórmula:C8H10FN3O3SPureza:100% - 99.78%Cor e Forma:White PowderPeso molecular:247.25Emtricitabine triphosphate tetrasodium salt
CAS:Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleosideFórmula:C8H9FN3Na4O12P3SPureza:98%Cor e Forma:SolidPeso molecular:575.11Delavirdine mesylate
CAS:Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).Fórmula:C23H32N6O6S2Pureza:99.99%Cor e Forma:Light Brown SolidPeso molecular:552.67Rilpivirine
CAS:Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatmentFórmula:C22H18N6Pureza:97.22% - 98.83%Cor e Forma:SolidPeso molecular:366.42Ref: TM-T2330
2mg38,00€5mg55,00€10mg88,00€25mg145,00€50mg243,00€100mg359,00€500mg842,00€1mL*10mM (DMSO)80,00€Tenofovir alafenamide
CAS:Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.Fórmula:C21H29N6O5PPureza:99% - 99.81%Cor e Forma:SolidPeso molecular:476.47NNRT-IN-5
CAS:NNRT-IN-5 (compound 10d) is an orally available non-nucleoside reverse transcriptase (Reverse Transcriptase) inhibitor.Fórmula:C27H22N8Cor e Forma:SolidPeso molecular:458.52Adefovir
CAS:Adefovir: acyclic nucleoside phosphonate, reverse transcriptase inhibitor for hepatitis B and herpes treatment.Fórmula:C8H12N5O4PPureza:99.56%Cor e Forma:White To Off-White PowderPeso molecular:273.19Nevirapine
CAS:Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor.Fórmula:C15H14N4OPureza:99.58% - 99.59%Cor e Forma:White Or Off-White Crystalline PowderPeso molecular:266.3ddUTP
CAS:ddUTP (2′,3′-Dideoxyuridine-5′-triphosphate) serves as a selective inhibitor of HIV and AMV reverse transcriptases with Ki values of 0.05 µM for HIV and 1 µMFórmula:C9H15N2O13P3Pureza:98%Cor e Forma:SolidPeso molecular:448.111Daidzin
CAS:Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.Fórmula:C21H20O9Pureza:98.20% - 99.43%Cor e Forma:White PowderPeso molecular:416.38
