Redutase
Redutases são uma ampla classe de enzimas que catalisam a redução de moléculas em várias vias bioquímicas. Em endocrinologia, redutases específicas, como a 5α-redutase, são cruciais para o metabolismo dos hormônios esteroides, incluindo a conversão de testosterona em diidrotestosterona (DHT). Inibidores de enzimas redutases são usados no tratamento de condições como hiperplasia prostática benigna e alopecia androgênica. Na CymitQuimica, oferecemos uma variedade de inibidores de redutase de alta qualidade para apoiar sua pesquisa em regulação hormonal, vias metabólicas e desenvolvimento terapêutico.
Produtos da "Redutase"
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Trimethoprim
CAS:Trimethoprim (NSC-106568) inhibits dihydrofolate reductase, CYP2C8, and OCT2 - an antibacterial agent.Fórmula:C14H18N4O3Pureza:99.80% - 99.81%Cor e Forma:White To Yellowish PowderPeso molecular:290.32COH29
CAS:COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.Fórmula:C22H16N2O5SPureza:97.04% - 98.92%Cor e Forma:SolidPeso molecular:420.44Ref: TM-T3157
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg217,00€50mg354,00€100mg590,00€1mL*10mM (DMSO)87,00€Alrestatin
CAS:Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle inFórmula:C14H9NO4Pureza:99.23%Cor e Forma:SolidPeso molecular:255.2256Ranirestat
CAS:Ranirestat (AS-3201) is an AR inhibitor with neuroprotective properties that improves peripheral nerve dysfunction in rats with advanced diabetic polyneuropathyFórmula:C17H11BrFN3O4Pureza:96.10% - 99.44%Cor e Forma:SolidPeso molecular:420.19Ref: TM-T16723
1mg79,00€5mg172,00€10mg264,00€25mg560,00€50mg898,00€100mg1.415,00€1mL*10mM (DMSO)182,00€Aurothiomalate sodium
CAS:Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.Fórmula:C4H3AuNa2O4SPureza:99.66%Cor e Forma:SoildPeso molecular:390.07Minalrestat
CAS:Minalrestat(ARI-509) is an orally active and potent aldose reductase inhibitor for the study of impaired microvascular reactivity in diabetic patients.Fórmula:C19H11BrF2N2O4Pureza:100% - 98.79%Cor e Forma:SolidPeso molecular:449.2Zopolrestat
CAS:Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM).Fórmula:C19H12F3N3O3SPureza:98.09%Cor e Forma:SolidPeso molecular:419.38Ref: TM-T35317
1mg35,00€2mg48,00€5mg70,00€10mg92,00€25mg202,00€50mg313,00€100mg465,00€1mL*10mM (DMSO)87,00€2-Chloro-1-(4-fluorobenzyl)benzimidazole
CAS:2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).Fórmula:C14H10ClFN2Pureza:99.64%Cor e Forma:SolidPeso molecular:260.69Methotrexate disodium
CAS:Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitorFórmula:C20H20N8Na2O5Pureza:99.77% - 99.96%Cor e Forma:SolidPeso molecular:498.4Quercetin 3-gentiobioside
CAS:Quercetin 3-gentiobioside from A. iwayomogi blocks AR and stops AGEs formation.Fórmula:C27H30O17Pureza:99.29% - 99.77%Cor e Forma:SolidPeso molecular:626.52Lidorestat
CAS:Lidorestat (IDD-676) is an aldose reductase inhibitor (IC50: 5 nM) with effective, selective and oral activity.Fórmula:C18H11F3N2O2SPureza:99.84%Cor e Forma:SolidPeso molecular:376.35Fidarestat
CAS:Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively).Fórmula:C12H10FN3O4Pureza:98%Cor e Forma:SolidPeso molecular:279.22Methotrexate
CAS:Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.Fórmula:C20H22N8O5Pureza:96.84% - 99.46%Cor e Forma:Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisPeso molecular:454.44Sulindac sulfone
CAS:Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac. Sulindac sulfone is an inhibitor of aldose reductase (IC50 =367 nM).Fórmula:C20H17FO4SPureza:98.19% - 98.83%Cor e Forma:SolidPeso molecular:372.41Ref: TM-T23403
5mg55,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€200mg409,00€1mL*10mM (DMSO)55,00€Risarestat
CAS:Risarestat (CT-112) is a potent aldose reductase inhibitor and thyroid hormone receptor (TR) antagonist for the treatment of hypoglycemia.Fórmula:C16H21NO4SPureza:98.39%Cor e Forma:SolidPeso molecular:323.41(R)-Viloxazine Hydrochloride
CAS:(R)-Viloxazine Hydrochloride, the R-isomer of Viloxazine.Fórmula:C13H20ClNO3Pureza:99.29% - 99.48%Cor e Forma:SolidPeso molecular:273.76Ref: TM-T22413
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg472,00€100mg645,00€200mg868,00€1mL*10mM (DMSO)145,00€EBPC
CAS:EBPC is an inhibitor of aldose reductase.Fórmula:C14H15NO4Pureza:99.55%Cor e Forma:SolidPeso molecular:261.27Ref: TM-T22757
1mg57,00€2mg74,00€5mg104,00€10mg158,00€25mg275,00€50mg394,00€100mg560,00€200mg757,00€1mL*10mM (DMSO)117,00€Izonsteride
CAS:Izonsteride (LY320236) is a selective and potent 5alpha reductase inhibitor with dual action on the type I and type II isoforms of the enzyme.Izonsteride isFórmula:C24H26N2OS2Pureza:99.55%Cor e Forma:SolidPeso molecular:422.61MK 0434
CAS:MK 0434 is a steroid 5α-reductase inhibitor and hormone antagonist associated with a significant reduction in DHT.Fórmula:C25H31NO2Pureza:98.27% - 98.43%Cor e Forma:SolidPeso molecular:377.52AT-007
CAS:AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM).Fórmula:C17H10F3N3O3S2Pureza:99.36%Cor e Forma:SolidPeso molecular:425.4Ref: TM-T10393
1mg66,00€5mg111,00€10mg180,00€25mg329,00€50mg533,00€100mg743,00€1mL*10mM (DMSO)124,00€
