GPR
Os receptores acoplados à proteína G (GPRs) são uma grande família de receptores de superfície celular que desempenham um papel crucial na transmissão de sinais de hormônios, neurotransmissores e outros ligantes extracelulares para o interior da célula. Os GPRs estão envolvidos em uma ampla gama de processos fisiológicos, incluindo regulação hormonal, resposta imune e percepção sensorial. Modificar a atividade dos GPRs é uma estratégia chave no desenvolvimento de terapias para várias doenças, incluindo distúrbios endócrinos, doenças cardiovasculares e condições neurológicas. Na CymitQuimica, oferecemos uma seleção de moduladores de GPR de alta qualidade para apoiar sua pesquisa em sinalização celular, endocrinologia e descoberta de medicamentos.
Produtos da "GPR"
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GPR84 antagonist 8
CAS:GPR84 antagonist 8 is a selective GPR84 antagonist.Fórmula:C23H23N3O5Cor e Forma:SolidPeso molecular:421.45TC-O 9311 free base
CAS:TC-O 9311 is a potent GPR139 agonist.Fórmula:C20H19N3O4Pureza:99.24%Cor e Forma:SoildPeso molecular:365.39Ref: TM-T4626
Produto descontinuadoMS 15203
CAS:MS 15203 is a GPR171 agonist that reduces chronic neuropathic and inflammatory pain in male mice.Fórmula:C12H11NO5Pureza:99.53%Cor e Forma:SolidPeso molecular:249.22Ref: TM-T37131
2mg46,00€5mg66,00€10mg104,00€25mg210,00€50mg311,00€100mg467,00€500mg1.017,00€1mL*10mM (DMSO)74,00€Setipiprant
CAS:Setipiprant (ACT-129968) is an oral CRTH2 antagonist for asthma/allergy, targeting PGD2-induced inflammation (IC50: 6.0 nM).Fórmula:C24H19FN2O3Pureza:99.16%Cor e Forma:SolidPeso molecular:402.42AZ12216052
CAS:AZ12216052 is a GRP8 antagonist with anxiolytic and anti-inflammatory activity and can be used to study obesity and metabolic disorders.Fórmula:C19H22BrNOSPureza:99.29%Cor e Forma:SolidPeso molecular:392.35TAK-875 Hemihydrate
CAS:TAK-875 Hemihydrate (Fasiglifam) is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid.Fórmula:C29H32O7SH2OPureza:98%Cor e Forma:SolidPeso molecular:533.63GSK137647A
CAS:GSK137647A (GSK 137647) is a selective FFA4 agonist.Fórmula:C16H19NO3SPureza:99.26% - 99.87%Cor e Forma:SolidPeso molecular:305.39Ref: TM-T3171
2mg35,00€5mg51,00€10mg85,00€25mg155,00€50mg245,00€100mg424,00€200mg613,00€500mg938,00€1mL*10mM (DMSO)57,00€MK 1903
CAS:MK 1903 is a strong, selective HCA2/GPR109A agonist, reducing cAMP in CHO cells with EC50 of 12.9 nM.Fórmula:C8H8N2O2Pureza:99.87%Cor e Forma:SolidPeso molecular:164.16VER-155008
CAS:VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.Fórmula:C25H23Cl2N7O4Pureza:98.88% - 99.55%Cor e Forma:SolidPeso molecular:556.4Ref: TM-T7010
2mg47,00€5mg69,00€10mg93,00€25mg163,00€50mg283,00€100mg467,00€200mg653,00€1mL*10mM (DMSO)85,00€ATC 0175 hydrochloride
CAS:ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective.Fórmula:C23H26ClF2N5OPureza:99.84%Cor e Forma:SolidPeso molecular:461.93Kuwanon H
CAS:Kuwanon H is a potent non-peptide GRP receptor antagonist with a Ki of 290 nM, useful in GRP-related studies.Fórmula:C45H44O11Pureza:97.99%Cor e Forma:SolidPeso molecular:760.821-methoxycyclopropanecarboxylic acid
CAS:1-methoxycyclopropanecarboxylic acid is an agonist of free fatty acid receptor 3 (FFAR3, human).Fórmula:C5H8O3Pureza:99.44%Cor e Forma:Light-Yellow To Yellow Solid Or LiquidPeso molecular:116.12GPR35 agonist 2
CAS:GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM,Fórmula:C17H11FN2O3SPureza:97.18% - 98.40%Cor e Forma:SolidPeso molecular:342.34Ref: TM-T23434
1mg52,00€5mg96,00€10mg170,00€25mg378,00€50mg560,00€100mg800,00€500mg1.644,00€1mL*10mM (DMSO)114,00€GPR120 Agonist 1
CAS:GPR120 Agonist 1 selectively activates human/mouse GPR120 with EC50 of 42/77 nM in HEK293 cells.Fórmula:C20H12ClF6NO3SPureza:98%Cor e Forma:SolidPeso molecular:495.823-chloro-5-hydroxybenzoic Acid
CAS:3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 : 16 μM)Fórmula:C7H5ClO3Pureza:98%Cor e Forma:SolidPeso molecular:172.57AH-7614
CAS:AH-7614 (AH 7614) is a selective and potent free fatty acid receptor 4 (FFA4/GPR120) antagonist.Fórmula:C20H17NO3SPureza:98.05%Cor e Forma:SolidPeso molecular:351.42Ref: TM-T22027
5mg51,00€10mg90,00€25mg173,00€50mg311,00€100mg424,00€200mg552,00€500mg715,00€1mL*10mM (DMSO)64,00€TUG-1375
CAS:TUG-1375 is an Agonist of Thiazolidine Free Fatty Acid Receptor 2Fórmula:C22H19ClN2O4SPureza:97.72% - 99.41%Cor e Forma:SolidPeso molecular:442.92Ref: TM-T7796
1mg133,00€5mg323,00€10mg527,00€25mg822,00€50mg1.103,00€100mg1.483,00€500mg2.965,00€1mL*10mM (DMSO)354,00€D-Kynurenine
CAS:D-Kynurenine, ZINC901103, metabolizes from D-tryptophan, activates AhR, changes epithelium to mesenchyme, and tests for D-amino acid oxidase.Fórmula:C10H12N2O3Pureza:97.08%Cor e Forma:SolidPeso molecular:208.21Kynurenic acid
CAS:Kynurenic acid (Quinurenic acid) is an NMDA, glutamate, α7 nicotinic acetylcholine receptor triple antagonist and GPR35/CXCR8 agonist.Fórmula:C10H7NO3Pureza:99.69%Cor e Forma:SolidPeso molecular:189.17PU-H54
CAS:PU-H54 is a purine-derived Grp94 inhibitor targeting the S2 subpocket's unique binding region.Fórmula:C18H19N5SPureza:99.13%Cor e Forma:SolidPeso molecular:337.44
