Enzima

PARP Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Sialidases have been suggested to be pathogenic factors in microbial infections.

TECR Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system with N-10xHis. The accession number is Q9NZ01.

Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis.

MTA/SAH nucleosidase Protein, E.

Granzyme A/GZMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. The CalB01 IA lipase has been immobilized on a hydrophobic carrier by adsorption. The immobilized CalB01 lipase has a temperature optimum in the 40 - 50 °C range and pH optimum between pH 5 and 8.

PPIases accelerate the folding of proteins.

3-Hydroxybutyrate Dehydrogenase Type 2 belongs to the short-chain dehydrogenases/reductases (SDR) family.

Alterations in GFER gene have been associated with progressive mitochondrial myopathy, congenital cataracts, hearing loss, developmental delay, lactic acidosis

N/A.

The metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription.

Lipase 14 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 6-8 and temp. optimum at 30-40°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 14 was shown to hydrolyze p-Nitrophenyl esters of butyrate (74 % activity compared to octanoate), octanoate (100 %), laurate (8 %), palmitate (5 %), stearate (4 %), arachidate (1 %) and behenate (0.6 %).

Lipase 64 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 7 and temp. optimum at 40-50°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 64 was shown to hydrolyze p-Nitrophenyl esters of butyrate (100 % activity), octanoate (0.5 %) and laurate (0.1 %).

Ubiquitin-Conjugating Enzyme E2 G2 (UBE2G2) is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation, which belong to

GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His) is expressed in Yeast.

Glucokinase belongs to the bacterial glucokinase family.

CS2 hydrolase (Carbon disulfide hydrolase; E.C. 3.13.1.5) is an enzyme that catalyzes the following reaction:  CS2 + 2 H2O → CO2 + 2 H2S  thus converting carbon disulfide into hydrogen sulfide and carbon dioxide.

Invertase is an enzyme that catalyzes the hydrolysis of sucrose to glucose and fructose and can be found in plants and microorganisms

Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.

Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia.

TYK2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag.

Carbohydrate sulfotransferase 15, also known as N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase, GalNAc4S-6ST, B-cell RAG-associated gene protein, CHST15

Carboxymethylenebutenolidase (CMBL), also known as 4-carboxymethylenebut-2-en-4-olide lactonohydrolase, maleylacetate enol- lactonase, dienelactone hydrolase,

Dual specificity kinase.

Metalloprotease that cleaves substrates preferentially between Phe-Phe residues.

Catalyzes the biosynthesis of agmatine from arginine.

PIP4K2B Protein, Human, Recombinant (His) is expressed in E.

MMP1, also known as MMP-1, contains 4 hemopexin-like domains and is a member of the matrix metalloproteinase (MMP) family.

Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.

Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln.

PLA2G2D Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

GUCY2C Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Licraside is a tyrosinase inhibitor with an IC50 of 0.072 mM for monophenolase and can be used in studies about antibrowning and depigmenting agents.

PDE9A Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

HK1 Protein, Human, Recombinant (His) is expressed in E. coli.

Carboxypeptidase Q (Cpq) is a member of the peptidase M28 family.

PTPRZ1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.

Anionic trypsin Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.

PPP3CA, also known as protein phosphatase 2B, is a member of the PPP phosphatase family, PP-2B subfamily.

Glucosyltransferase206-freeze dried is an enzymatic preparation designed for specific biochemical applications. It is derived from microbial sources, where it is produced and purified through advanced biotechnological processes. The enzyme functions by catalyzing the transfer of glucosyl units from donor molecules to specific acceptors, thereby forming glycosidic bonds. This mode of action is crucial in various biosynthetic pathways, particularly in the production of polysaccharides and structural carbohydrates. The utility of Glucosyltransferase206-freeze dried spans multiple scientific fields, including biotechnology, pharmaceuticals, and food chemistry. It is widely employed in the synthesis of oligosaccharides and glycoconjugates, which are essential in the development of therapeutic agents, functional foods, and bio-based materials. Researchers utilize this enzyme to study carbohydrate metabolism and to engineer glucoside derivatives with tailored properties. Its robust performance in catalyzing specific reactions makes it a valuable tool for scientists exploring innovative applications in glycoscience.

Key enzyme in folate metabolism.

CAMKI Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 41.5 kDa and the accession number is B0YIY3.

PCSK9 Protein, Human, Recombinant (D374Y, mFc), Biotinylated is expressed in HEK293 mammalian cells with mFc tag.

GPD2 Protein, Candida albicans, Recombinant (His) is expressed in yeast with C-6xHis tag.

This enzyme hydrolyzes cefotaxime, ceftazidime and other broad spectrum cephalosporins.

GUCY2C Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

IL-1R1 Protein, Rat, Recombinant (His & mFc) is expressed in HEK293 mammalian cells with His, mFc tag.

Clavin has the same substrate specificity as alpha-sarcin.

PPIB is identified as a candidate gene for OI-IX.

HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.

Chloroperoxidase (also known as chloride peroxidase, systemic name chloride:hydrogen-peroxide oxidoreductase, EC 1.11.1.10) is an enzyme that catalyzes chlorination of organic compounds. Overall reaction is the following:R-H + Cl− + H2O2 + H+ → R-Cl + 2 H2O; reaction intermediate is hypochlorous acid (HOCl). One unit of chloroperoxidase will convert 1.0 μmole of substrate per minute.

Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.

Hydrolytic enzyme; biocatalyst in production of beta-lactam antibiotics

Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc) is expressed in E. coli.

May have a protective function during conditions of oxidative stress.

Src Protein, Human, Recombinant (His) is expressed in E. coli.

CGTases Protein, Paenibacillus macerans, Recombinant (His) is expressed in yeast with N-6xHis tag.

Enterokinase is a member of the trypsin family of serine proteases.

Methyl rosmarinate, from Rabdosia serra, inhibits tyrosinase (IC50: 0.28 mM), α-glucosidase, MMP-1, and has antioxidant, antifungal properties.

ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E.

PIN1 Protein, Human, Recombinant (His) is expressed in E.

HGD Protein, Human, Recombinant (His) is expressed in E.

Catalyzes the attachment of pyrrolysine to tRNA(Pyl).

Tryptases are serine proteases with trypsin-like specificity.

Isoderrone inhibits α-glucosidase and PTP1B; IC50 = 22.7 uM, potential type 2 diabetes drug.

MKNK1 Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q9BUB5.

PRKCH Protein, Human, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is P24723.

Myeloperoxidase (MPO) is a hemecontaining enzyme belonging to the XPO subfamily of peroxidases.

ACE2/ACEH Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag.

Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.

PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2.

PLA2G10 Protein, Rat, Recombinant (His & Myc) is expressed in E.

UCHL3 Protein, Rat, Recombinant (His) is expressed in E.

Pyruvate kinase (from Rabbit muscle), ammonium sulfate suspension is an enzyme product, which is a purified protein extracted from the muscle tissue of rabbits. This enzyme plays a crucial role in glycolysis, specifically catalyzing the transphosphorylation of phosphoenolpyruvate (PEP) to pyruvate, generating ATP from ADP in the process. This step is a key regulatory point in the glycolytic pathway, which is essential for cellular energy production. The primary mode of action of pyruvate kinase is to facilitate the conversion of PEP to pyruvate by transferring a phosphate group to ADP, yielding ATP. This reaction is crucial for maintaining the flow of carbon intermediates through glycolysis, which ultimately contributes to the cellular ATP pool critical for various physiological processes. Pyruvate kinase from rabbit muscle is widely used in biochemical research to study metabolic pathways and enzyme kinetics. Its applications extend to exploring the regulation of glycolysis, elucidating energy metabolism, and examining allosteric effects and enzyme structure-function relationships. Additionally, this enzyme serves as a model for studying similar enzymes in other organisms, contributing to a broader understanding of metabolic control and energy balance in cells.

HER3/ERBB3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

The enzyme has great affinity for glucose and mannose.

Legumain Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes,

ADAR Protein, Mouse, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q99MU3.

GSTM5 Protein, Human, Recombinant (His) is expressed in E.

CNOT7 Protein, Human, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is Q9UIV1.

E3 ubiquitin-protein ligase that mediates the polyubiquitination of lysine and cysteine residues on target proteins, such as CD3D, CYP3A4, CFTR, INSIG1, SOAT2/

LacBuster™-S 2000 is an enzyme preparation, specifically a beta-lactamase, which is derived from bacterial sources known for their capacity to degrade beta-lactam antibiotics. Through hydrolytic cleavage of the beta-lactam ring, this enzyme neutralizes the efficacy of beta-lactam antibiotics, thereby rendering them inactive. The primary function of LacBuster™-S 2000 is to hydrolyze the beta-lactam ring found in antibiotics such as penicillins and cephalosporins. By breaking this chemical structure, the enzyme effectively eliminates the antibiotic activity, allowing for studies in environments otherwise sensitive to the presence of beta-lactams. This product is utilized extensively in microbiological and biochemical research labs, particularly in studies requiring the selective inactivation of beta-lactam antibiotics. It aids in the maintenance of bacterial cultures or assays where the presence of beta-lactam antibiotics could interfere with experimental outcomes. LacBuster™-S 2000 is an invaluable tool in studies of antibiotic resistance and bacterial enzyme activity.

ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

MPK5 Protein, Japonica rice, Recombinant (His & Myc) is expressed in E.

Polymerizes silica around the axial filament during spicule formation.

Glucosyltransferase (GTase) is the enzyme that transfers glucose to another organic molecule (aglycon), establishing glycosidic linkage. UDP-glucose dependent GTases are part of the enzyme family of glucosyltransferases, they are versatile tools in glucosylation reactions. Different GTases have different substrate specificities. For the specificity of GT227 Glucosyltransferase, please see Table 1 that lists the available GTases with GT227 highlighted.Color: beigeForm: lyophilisateProtein content: 0.8 mg/mgThe glucosyltransferase was tested in a glucosylation reaction of a preferred substrate. High conversion after up to 24 h reaction time was observed. Not sure which GTase to choose? Consider our Glucosyltransferase kit, which contains all 8 Glucosyltransferases.

HDAC10 Protein, Human, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is Q969S8.

DXO Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is O77932.

Alpha Amylase (Amylase, α-Amylase, 1,4-α-D-glucan glucanohydrolase, glycogenase, PPA; systematic name 4-α-D-glucan glucanohydrolase; EC 3.2.1.1, CAS Number [9000-90-2]) is an enzyme that catalyzes hydrolysis of large polysaccharides into smaller fragments. Alpha amylase targets alpha bonds of 1→4 glycosidic linkages of poly- and oligosaccharides with three or more D-glucose units. One unit of Alpha Amylase will catalyze the hydrolysis of 1.0 μmol of 2-chloro-4-nitrophenyl-α-D-maltotrioside to yield 2-chloro-4-nitrophenol per minute at 37°C. Porcine pancreatic Alpha Amylase is supplied as lyophilized, off-white to white powder, lyophilized from tris chloride and mannitol, pH 7.2. Activity is ≥70U/mL, specific activity ≥100 U/mg protein. Store at -20°C on arrival.

Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP.

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

TRIM5 Protein, Human, Recombinant (B2M & His) is expressed in E.