Nrf2
Nrf2 é um fator de transcrição que regula a expressão de proteínas antioxidantes e enzimas de desintoxicação, desempenhando um papel fundamental na defesa celular contra o estresse oxidativo e a inflamação. A ativação da sinalização Nrf2 oferece proteção contra várias doenças, incluindo câncer, neurodegeneração e distúrbios cardiovasculares. Os moduladores de Nrf2 estão sendo explorados por suas potenciais aplicações terapêuticas na redução de danos oxidativos e inflamação. Na CymitQuimica, oferecemos uma gama de moduladores da via Nrf2 de alta qualidade para apoiar sua pesquisa em estresse oxidativo, inflamação e prevenção de doenças.
Produtos da "Nrf2"
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35 produtos desta categoria.
NK-252
CAS:NK-252 is a potential activator of Nrf2. It has great Nrf2-activating potential.Fórmula:C13H11N5O3Pureza:98.32%Cor e Forma:SolidPeso molecular:285.26KI696
CAS:KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.Fórmula:C28H30N4O6SPureza:98.42%Cor e Forma:SolidPeso molecular:550.63Ref: TM-T11758L
1mg144,00€5mg350,00€10mg558,00€25mg1.026,00€50mg1.406,00€100mg1.872,00€1mL*10mM (DMSO)449,00€Anti-NFE2L2 Antibody (9K94)
Anti-NFE2L2 Antibody (9K94) is a Mouse antibody targeting NFE2L2. Anti-NFE2L2 Antibody (9K94) can be used in ELISA, WB, IHC, IF, FCM.Pureza:>95%Cor e Forma:Odour LiquidML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Fórmula:C23H22Cl2N2O3SPureza:98.42% - 99.78%Cor e Forma:SolidPeso molecular:477.4NSC23925
CAS:NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).Fórmula:C22H26Cl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:421.36Rehmapicrogenin
CAS:Rehmapicrogenin regulates the Nrf2/ARE signaling pathway. Nrf2/ARE signaling pathway is the most important pathway of oxidative stress.Fórmula:C10H16O3Pureza:98%Cor e Forma:SolidPeso molecular:184.23Kinsenoside
CAS:Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.Fórmula:C10H16O8Pureza:100% - 99.92%Cor e Forma:SolidPeso molecular:264.23VVD-130037
CAS:VVD-130037 is a KEAP1 activator with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.Fórmula:C17H17ClN4O2Pureza:99.01%Cor e Forma:SolidPeso molecular:344.8CDDO-EA
CAS:CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.Fórmula:C33H46N2O3Pureza:98.54%Cor e Forma:SolidPeso molecular:518.73Ref: TM-T10733
1mg85,00€5mg169,00€10mg298,00€25mg512,00€50mg732,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)187,00€Ezetimibe
CAS:Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.Fórmula:C24H21F2NO3Pureza:97.28% - 99.97%Cor e Forma:SolidPeso molecular:409.43Ref: TM-T1593
1g283,00€10mg48,00€25mg62,00€50mg77,00€100mg87,00€200mg125,00€500mg197,00€1mL*10mM (DMSO)55,00€(E/Z)-BCI
CAS:(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROSFórmula:C22H23NOPureza:98.55%Cor e Forma:SolidPeso molecular:317.42Ref: TM-T11139
1mg80,00€5mg155,00€10mg283,00€25mg452,00€50mg638,00€100mg848,00€200mg1.121,00€1mL*10mM (DMSO)170,00€4-Octyl itaconate
CAS:4-Octyl Itaconate is a cell-permeable derivative of Itaconate, an anti-inflammatory metabolite.Fórmula:C13H22O4Pureza:99.3% - 99.94%Cor e Forma:SolidPeso molecular:242.31CPUY192018
CAS:CPUY192018 is an inhibitor of Keap1-Nrf2 protein-protein interactions, and can be used to study mitochondrial autophagy.Fórmula:C28H26N2O10S2Pureza:98.9%Cor e Forma:SolidPeso molecular:614.64TAT 14
CAS:TAT 14: a 14-mer peptide Nrf2 activator, anti-inflammatory, boosts Nrf2 protein, targets Keap1, no effect on mRNA.Fórmula:C137H230N48O39Pureza:98%Cor e Forma:SolidPeso molecular:3173.59ML334
CAS:ML334 (LH601A) is an NRF2 activator that inhibits cardiac fibroblast activation and proliferation ameliorating myocardial infarction-induced cardiac fibrosis.Fórmula:C26H26N2O5Pureza:98.06% - 98.06%Cor e Forma:SolidPeso molecular:446.49CBR-470-1
CAS:CBR-470-1 is a glycolytic phosphoglycerate kinase 1 inhibitor and Nrf2 activator that exhibits neuroprotective activity by activating the Keap1-Nrf2 cascade.Fórmula:C14H20ClNO4S2Pureza:98.03%Cor e Forma:SolidPeso molecular:365.9RA-839
CAS:RA-839 is a Keap1 conjugate and Nrf2 signaling activator, and an inhibitor of Keap1/Nrf2 interaction with anticancer activity.Fórmula:C25H28N2O4SPureza:98.38%Cor e Forma:SolidPeso molecular:452.57Gingerenone A
CAS:Gingerenone A, an Nrf2-Gpx4 activator isolated from ginger, has anticancer activity and inhibits iron death in mice with colitis secondary to liver injury (SLI)Fórmula:C21H24O5Pureza:98.94%Cor e Forma:SolidPeso molecular:356.41Nrf2 activator-1
CAS:Nrf2 activator-1 activates Nrf2; used for COPD, asthma, ALI, ARDS, pulmonary fibrosis research.Fórmula:C30H34N4O6SPureza:≥98%Cor e Forma:SolidPeso molecular:578.68KI696 isomer
CAS:KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases.Fórmula:C28H30N4O6SPureza:99.8%Cor e Forma:SolidPeso molecular:550.63Ref: TM-T11758
1mg154,00€5mg464,00€10mg777,00€25mg1.568,00€50mg2.110,00€100mg2.783,00€1mL*10mM (DMSO)510,00€Brusatol
CAS:Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.Fórmula:C26H32O11Pureza:99.35% - 99.82%Cor e Forma:SolidPeso molecular:520.53Ref: TM-TQ0211
1mg39,00€5mg94,00€10mg160,00€25mg311,00€50mg502,00€100mg715,00€200mg938,00€1mL*10mM (DMSO)107,00€DDO-7263
CAS:DDO-7263, a 1,2,4-Oxadiazole, boosts Nrf2 by binding Rpn6, blocking 26S proteasome assembly, and has anti-inflammatory effects.Fórmula:C14H9F2N3OPureza:99.75%Cor e Forma:SolidPeso molecular:273.24Nrf2-IN-3
CAS:Nrf2-IN-3 is an NRF2 inhibitor that selectively sensitizes xenografts of mouse mKEAP1 cancer cells to cisplatin.Fórmula:C22H26N4O4SPureza:98.07%Cor e Forma:SolidPeso molecular:442.53Ref: TM-T78841
1mg65,00€5mg139,00€10mg217,00€25mg411,00€50mg658,00€100mg1.035,00€200mg1.396,00€1mL*10mM (DMSO)154,00€4-P-PDOT
CAS:4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.Fórmula:C19H21NOPureza:99.68%Cor e Forma:SolidPeso molecular:279.38Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851)
Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) is an antibody targeting Phospho-NFE2L2 (Ser40). Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) can be used in ELISA, WB, IHC, IF.Cor e Forma:Odour Liquid(E)-[6]-Dehydroparadol
CAS:(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.Fórmula:C17H24O3Pureza:99.87%Cor e Forma:SolidPeso molecular:276.37Ref: TM-T13436
1mg44,00€5mg93,00€10mg116,00€25mg207,00€50mg283,00€100mg406,00€500mg919,00€1mL*10mM (DMSO)93,00€AEM1
CAS:AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.Fórmula:C20H14FN3O2SPureza:98.37%Cor e Forma:SolidPeso molecular:379.41Ref: TM-T8979
2mg38,00€5mg51,00€10mg92,00€25mg170,00€50mg298,00€100mg510,00€200mg737,00€1mL*10mM (DMSO)60,00€Nrf2-IN-1
CAS:Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).Fórmula:C21H22ClN3O2Pureza:95.00% - 99.68%Cor e Forma:SolidPeso molecular:383.87Ref: TM-T12253
1mg78,00€5mg169,00€10mg230,00€25mg383,00€50mg537,00€100mg748,00€200mg1.035,00€1mL*10mM (DMSO)301,00€AA147
CAS:AA147 is an ER proteostasis regulator that selectively activates the ATF6 arm of UPR as a prodrug.Fórmula:C16H17NO2Pureza:99.24%Cor e Forma:SolidPeso molecular:255.31Ref: TM-T14080
5mg63,00€10mg96,00€25mg178,00€50mg265,00€100mg395,00€500mg894,00€1mL*10mM (DMSO)69,00€Anti-NFE2L2 Antibody (6K859)
Anti-NFE2L2 Antibody (6K859) is an antibody targeting NFE2L2. Anti-NFE2L2 Antibody (6K859) can be used in ELISA, IF.Cor e Forma:Odour LiquidK67
CAS:K67 competitively inhibits the interaction between Nrf2-ETGE and Keap1 and can be used to study cancer.Fórmula:C29H30N2O7S2Pureza:98.43%Cor e Forma:SolidPeso molecular:582.69Eriodictyol-7-O-glucoside
CAS:Eriodictyol-7-O-glucoside, a flavonoid in pistachio skin, activates Nrf2 and protects against Cisplatin toxicity.Fórmula:C21H22O11Pureza:99.53%Cor e Forma:SolidPeso molecular:450.39Trilobatin
CAS:Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFórmula:C21H24O10Pureza:97.16%Cor e Forma:SolidPeso molecular:436.41Ref: TM-T2S0731
1mg64,00€5mg124,00€10mg165,00€25mg323,00€50mg487,00€100mg710,00€1mL*10mM (DMSO)137,00€Artemisitene
CAS:Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.Fórmula:C15H20O5Pureza:99.58%Cor e Forma:SolidPeso molecular:280.32Ref: TM-T21065
1mg95,00€5mg187,00€10mg329,00€25mg560,00€50mg800,00€100mg1.103,00€1mL*10mM (DMSO)281,00€I-152
CAS:Bepranemab (UCB 0107) is a humanized IgG monoclonal antibody against tau for the study of Alzheimer's disease (AD) and tau proteinopathies.Fórmula:C9H16N2O3S2Pureza:98.36%Cor e Forma:SolidPeso molecular:264.37
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