SGK
A quinase regulada por soro e glucocorticoides (SGK) é uma proteína quinase envolvida na regulação de vários processos celulares, incluindo transporte de íons, sobrevivência celular e metabolismo da glicose. Os inibidores de SGK são valiosos no estudo de condições como hipertensão, diabetes e câncer, onde a atividade de SGK desempenha um papel crucial. Esses inibidores ajudam a entender as vias de sinalização reguladas por SGK e suas implicações nas doenças. Na CymitQuimica, oferecemos inibidores de SGK para apoiar sua pesquisa em transdução de sinal, doenças metabólicas e terapia contra o câncer.
Produtos da "SGK"
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10 produtos desta categoria.
GSK 650394
CAS:GSK 650394 is an inhibitor of serum- and glucocorticoid-regulated kinases (SGK). GSK 650394 has antitumor activity. Cost-effective and quality-assured.Fórmula:C25H22N2O2Pureza:100% - 98.93%Cor e Forma:SolidPeso molecular:382.45Ref: TM-T2622
1mg40,00€2mg52,00€5mg88,00€10mg111,00€25mg208,00€50mg376,00€100mg540,00€200mg663,00€1mL*10mM (DMSO)87,00€EMD638683
CAS:EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 μM).Fórmula:C18H18F2N2O4Pureza:98%Cor e Forma:SolidPeso molecular:364.34BRD7389
CAS:BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.Fórmula:C24H18N2O2Pureza:99.17%Cor e Forma:SolidPeso molecular:366.41SI-113
CAS:SI-113 is a potent and selective inhibitor of SGK1, a serine/threonine protein kinase, that modulates several oncogenic signaling cascades.Fórmula:C23H24N6OPureza:98.81%Cor e Forma:SolidPeso molecular:400.48Ref: TM-T9589
1mg46,00€2mg59,00€5mg87,00€10mg140,00€25mg250,00€50mg374,00€100mg547,00€1mL*10mM (DMSO)106,00€SGK1-IN-6
CAS:SGK1-IN-6 (compound 12f) is an SGK1 inhibitor with an IC50 value of 0.39 μM. In PC3 xenograft models using BALB/c nude mice, SGK1-IN-6 effectively hinders tumor growth without causing any observable toxicity.Fórmula:C30H30F3N5O4Cor e Forma:SolidPeso molecular:581.586PROTAC SGK3 degrader-1
CAS:PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligands to VH032 VHL to induce endogenous SGK3 degradation.Fórmula:C57H73FN10O11S2Pureza:98%Cor e Forma:SolidPeso molecular:1157.38SGK1-IN-4
CAS:SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.Fórmula:C23H21ClFN5O4SPureza:97.03%Cor e Forma:SolidPeso molecular:517.96Ref: TM-T9977
1mg111,00€5mg264,00€10mg376,00€25mg612,00€50mg825,00€100mg1.103,00€200mg1.483,00€1mL*10mM (DMSO)319,00€EMD638683 R-Form
CAS:EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM. EMD638683 R-Form is the R-form of EMD638683.Fórmula:C18H18F2N2O4Cor e Forma:SolidPeso molecular:364.34BN201
CAS:BN201 (OCS-05) is a neuroprotective drug by activating SGK2 and FOXO3 pathway. BN201 is able to regulate multiple kinases in the IGF1 pathway and cross BBB.Fórmula:C25H38FN5O4Pureza:99.73% - 99.73%Cor e Forma:SolidPeso molecular:491.6CKI-7
CAS:CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Fórmula:C11H14Cl3N3O2SPureza:100.00% - 100.00%Cor e Forma:SolidPeso molecular:358.67Ref: TM-T19913
1mg114,00€5mg217,00€10mg325,00€25mg525,00€50mg712,00€100mg959,00€200mg1.293,00€1mL*10mM (DMSO)239,00€
