Receptor de Retinóide
Os receptores de retinoides são receptores nucleares que mediam os efeitos dos retinoides (derivados da vitamina A) na expressão gênica. Esses receptores desempenham um papel vital na diferenciação celular, proliferação e apoptose. Inibidores dos receptores de retinoides são utilizados para estudar seu envolvimento em várias doenças, incluindo câncer, distúrbios de pele e condições metabólicas. Ao modular a atividade dos receptores de retinoides, esses inibidores podem fornecer insights sobre os mecanismos de sinalização dos retinoides e seu potencial terapêutico. Na CymitQuimica, oferecemos inibidores dos receptores de retinoides para apoiar sua pesquisa em dermatologia, oncologia e regulação metabólica.
Produtos da "Receptor de Retinóide"
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KCL-286
CAS:KCL-286 is an available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI).Fórmula:C19H14N2O4Pureza:99.93%Cor e Forma:SolidPeso molecular:334.33AC-261066
CAS:AC-261066 is an orally available and isoform-selective agonist of RARβ2 with a pEC50 of 8.0.Fórmula:C17H20FNO4SPureza:98.44%Cor e Forma:SolidPeso molecular:353.41LY2955303
CAS:LY2955303 is an effective and selective antagonist of retinoic acid receptor gamma (RARγ, Ki = 1.09 nM).Fórmula:C36H42N4O3Pureza:98.56% - 99.85%Cor e Forma:SolidPeso molecular:578.741,3,5-Triisopropylbenzene
CAS:1,3,5-Triisopropylbenzene is commonly used in fuels, lubricants, and micellar expanders, a potential retinoid X nuclear receptor alpha (RXRα) agonist.Fórmula:C15H24Pureza:95.84%Cor e Forma:SolidPeso molecular:204.35BMS 195614
CAS:BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.Fórmula:C29H24N2O3Pureza:97.7%Cor e Forma:SolidPeso molecular:448.51CD437
CAS:CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.Fórmula:C27H26O3Pureza:98.79% - 99.63%Cor e Forma:SolidPeso molecular:398.49Etodolac
CAS:Etodolac (AY-24236), a pyranocarboxylic NSAID, blocks COX-1/2, reducing pain, fever, inflammation, and inhibits platelet aggregation.Fórmula:C17H21NO3Pureza:99.78% - 99.92%Cor e Forma:Crystalline SolidPeso molecular:287.35Mofarotene
CAS:Mofarotene (Ro-40-8757) is a small molecule compound that shows considerable antitumor activity in many cancer cell lines and can be used for the treatment ofFórmula:C29H39NO2Pureza:99.36%Cor e Forma:SolidPeso molecular:433.63BMS641
CAS:BMS641 (BMS-209641) is a RARβ agonist with affinity for RARβ that synergistically activates RARβ and RARgamma to induce cell maturation.Fórmula:C27H23ClO2Pureza:98.98%Cor e Forma:SolidPeso molecular:414.92Ref: TM-T26854
1mg157,00€5mg376,00€10mg628,00€25mg1.216,00€50mg1.738,00€100mg2.347,00€1mL*10mM (DMSO)414,00€AR7
CAS:AR7 is a retinoic acid receptor α (RARα) antagonist.Fórmula:C15H12ClNOPureza:98.12% - 99.52%Cor e Forma:SolidPeso molecular:257.71Ref: TM-T3955
1mg37,00€5mg69,00€10mg96,00€25mg202,00€50mg329,00€100mg550,00€200mg758,00€500mg1.159,00€1mL*10mM (DMSO)74,00€CD3254
CAS:CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.Fórmula:C24H28O3Pureza:98.71% - 98.71%Cor e Forma:SolidPeso molecular:364.48AGN 194310
CAS:AGN 194310 (VTP-194310) is retinioic acid receptors (RARs) pan-antagonist. The Kd values of 3 nM, 2 nM, 5 nM for RARα, RARβ, RARγ, respectively[1][2].Fórmula:C28H24O2SCor e Forma:SolidPeso molecular:424.55AGN 193109
CAS:AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).Fórmula:C28H24O2Pureza:98.81% - 99.89%Cor e Forma:SolidPeso molecular:392.49AM580
CAS:AM580 (CD336) is a retinoic acid receptor agonist that is selective for RARα( IC50 : 8 nM )Fórmula:C22H25NO3Pureza:98% - 99.89%Cor e Forma:SolidPeso molecular:351.44Ref: TM-T5854
2mg39,00€5mg57,00€10mg87,00€25mg164,00€50mg316,00€100mg469,00€500mg1.064,00€1mL*10mM (DMSO)64,00€BMS270394
CAS:BMS270394 is a RARγ agonist used in the study of breast cancer and skin diseases.Fórmula:C23H26FNO4Cor e Forma:SolidPeso molecular:399.46PA452
CAS:PA452 is a selective antagonist of retinoic X receptor (RXR) and suppresses the effect of Retinoic acid on Th1/Th2 development.Fórmula:C26H37N3O3Pureza:96.76%Cor e Forma:SolidPeso molecular:439.59Ref: TM-T16425
1mg92,00€5mg250,00€10mg401,00€25mg657,00€50mg937,00€100mg1.283,00€1mL*10mM (DMSO)274,00€LE135
CAS:LE135: RARα/RARβ antagonist (Ki: 1.4 μM/220 nM), favors RARβ, selective vs RARγ/RXRs; also activates TRPV1/TRPA1 (EC50s: 2.5/20 μM).Fórmula:C29H30N2O2Pureza:98.33%Cor e Forma:SolidPeso molecular:438.56Ref: TM-T22920
1mg47,00€2mg62,00€5mg92,00€10mg135,00€25mg217,00€50mg324,00€100mg472,00€1mL*10mM (DMSO)97,00€Fenretinide
CAS:Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.Fórmula:C26H33NO2Pureza:98% - 99.72%Cor e Forma:Yellow PowderPeso molecular:391.55CD 1530
CAS:CD 1530 is an ARγ agonist (Kd:150 nM) with potential anticancer activity for the study of oral carcinogenesis.Fórmula:C27H26O3Pureza:98.13%Cor e Forma:SolidPeso molecular:398.49palovarotene
CAS:Palovarotene (Ro 3300074) is an agonist of nuclear retinoic acid receptor γ (RAR-γ).Fórmula:C27H30N2O2Pureza:96.89% - 98.05%Cor e Forma:SolidPeso molecular:414.54
