Anidrase carbónica
A anidrase carbônica é uma enzima que catalisa a conversão reversível de dióxido de carbono e água em bicarbonato e prótons. Esta enzima desempenha um papel crucial na manutenção do equilíbrio ácido-base, respiração e transporte de dióxido de carbono no sangue. Inibidores da anidrase carbônica são usados no tratamento de glaucoma, epilepsia e mal da altitude, bem como em pesquisas sobre homeostase ácido-base e troca gasosa. Na CymitQuimica, oferecemos uma gama de inibidores e reagentes de anidrase carbônica de alta qualidade para apoiar sua pesquisa em enzimologia, fisiologia respiratória e desenvolvimento terapêutico.
Produtos da "Anidrase carbónica"
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Compound CDy9
CAS:Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.Fórmula:C15H16N2O5SPureza:99.75%Cor e Forma:SoildPeso molecular:336.36Ref: TM-T67774
2mg38,00€5mg58,00€10mg96,00€25mg170,00€50mg253,00€100mg364,00€200mg512,00€1mL*10mM (DMSO)71,00€Benzolamide
CAS:Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.Fórmula:C8H8N4O4S3Pureza:97.03%Cor e Forma:SolidPeso molecular:320.37Ref: TM-T23782
5mg51,00€10mg88,00€25mg160,00€50mg235,00€100mg349,00€200mg515,00€1mL*10mM (DMSO)57,00€α-Glycosidase-IN-2
α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.Fórmula:C25H22N6OS2Cor e Forma:SolidPeso molecular:486.614-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
CAS:4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-Fórmula:C7H8F3N3O4S2Pureza:98.58%Cor e Forma:SolidPeso molecular:319.28Sultiame
CAS:Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.Fórmula:C10H14N2O4S2Pureza:99.86%Cor e Forma:SolidPeso molecular:290.36Cyclamic acid sodium
CAS:Sodium cyclamate is a carbonic anhydrase inhibitor, artificial sweetener, with anticonvulsant properties, and used in cancer research.Fórmula:C6H12NNaO3SPureza:99.84%Cor e Forma:SolidPeso molecular:201.22hCAI/II-IN-6
CAS:hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA).Fórmula:C19H24N4O3SPureza:97.07%Cor e Forma:SolidPeso molecular:388.48hCAIX-IN-15
CAS:hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancerFórmula:C18H14FN7O2SPureza:98%Cor e Forma:SolidPeso molecular:411.41hCAIX/XII-IN-8
CAS:hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.Fórmula:C16H13Cl2N5O3SPureza:98%Cor e Forma:SolidPeso molecular:426.28Benzthiazide
CAS:Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.Fórmula:C15H14ClN3O4S3Pureza:100% - 99.79%Cor e Forma:Crystals From Acetone SolidPeso molecular:431.94hCAIX/XII-IN-7
Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM forFórmula:C17H14N6O3SPureza:98%Cor e Forma:SolidPeso molecular:382.4CA IX/VEGFR-2-IN-3
CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.Fórmula:C19H16ClN3O5S2Peso molecular:465.93Histone acetyltransferase p300 Inhibitor 4c
CAS:2-Amino-4-(4-chlorophenyl)thiazole blocks hCA I/II, AChE, BChE with Ki: ~0.008, 0.124, 0.129, 0.083 µM.Fórmula:C9H7ClN2SPureza:99.86%Cor e Forma:SolidPeso molecular:210.68pNNP
CAS:pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.Fórmula:C6H6NO6PPureza:99.73%Cor e Forma:SolidPeso molecular:219.09Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.Cor e Forma:Lyophilized PowderPeso molecular:32.04 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.Benzenesulfonamide
CAS:Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.Fórmula:C6H7NO2SPureza:99.42% - 99.99%Cor e Forma:White Crystalline PowderPeso molecular:157.19Acetazolamide
CAS:Acetazolamide (Diamox) is a Carbonic Anhydrase Inhibitor. The mechanism of action of acetazolamide is as a Carbonic Anhydrase Inhibitor. The chemical classification of acetazolamide is Sulfonamides.Fórmula:C4H6N4O3S2Pureza:99.61% - 99.94%Cor e Forma:Crystals From Water 1992)Peso molecular:222.245hCA XII-IN-6
Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferativeFórmula:C11H9N5O3S2Pureza:98%Cor e Forma:SolidPeso molecular:323.35CA inhibitor 2
Compound 4H is a potent carbonic anhydrase inhibitor with an IC50 value of 0.033 μM [1].Fórmula:C7H9N7O3S3Pureza:98%Cor e Forma:SolidPeso molecular:335.39Carbonic anhydrase inhibitor 6
CAS:Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.Fórmula:C26H25N3O5SPureza:98.81%Cor e Forma:SolidPeso molecular:491.56
