AhR
O Receptor de Hidrocarbonetos Aromáticos (AhR) é um fator de transcrição ativado por ligantes que desempenha um papel crítico na regulação das respostas biológicas a contaminantes ambientais, como dioxinas. O AhR também está envolvido no metabolismo de xenobióticos e na regulação das respostas imunológicas, proliferação e diferenciação celular. A desregulação da sinalização do AhR está associada a várias doenças, incluindo câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma gama de inibidores de AhR para apoiar sua pesquisa em toxicologia, biologia do câncer e imunologia.
Produtos da "AhR"
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Skatole
CAS:Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Fórmula:C9H9NPureza:99.74%Cor e Forma:Leaves From Petroleum Ether; White-Brown Scales SolidPeso molecular:131.17VAF347
CAS:VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects.Fórmula:C17H11ClF3N3Pureza:98.75% - 99.55%Cor e Forma:SolidPeso molecular:349.74Ref: TM-T13276
1mg40,00€2mg51,00€5mg85,00€10mg119,00€25mg210,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)113,00€DiMNF
CAS:Imigliptin (KBP 3853) is a dipeptidyl peptidase-4 inhibitor used in the study of type 2 diabetes.Fórmula:C21H16O4Pureza:97.60%Cor e Forma:SolidPeso molecular:332.35(-)-Perillaldehyde
CAS:(-)-Perillaldehyde shows antibacterial activity.Fórmula:C10H14OPureza:90.68% - 97.21%Cor e Forma:Clear Light Yellow LiquidPeso molecular:150.22Tapinarof
CAS:Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.Fórmula:C17H18O2Pureza:100% - 99.84%Cor e Forma:SolidPeso molecular:254.32Ref: TM-T4644
1mg40,00€2mg52,00€5mg85,00€10mg124,00€25mg230,00€50mg350,00€100mg522,00€500mg1.130,00€1mL*10mM (DMSO)88,00€Diosmin
CAS:Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.Fórmula:C28H32O15Pureza:97.90%Cor e Forma:Greyish-Yellow Or Light Yellow Hygroscopic PowderPeso molecular:608.54Mexiletine hydrochloride
CAS:Mexiletine hydrochloride is a lidocaine-like antiarrhythmic (Class IB) and anesthetic, stabilizing heartbeats by inhibiting sodium in cardiac cells.Fórmula:C11H18ClNOPureza:99.88%Cor e Forma:White To Off-White SolidPeso molecular:215.72BAY-218
CAS:Bindarit (AF2838) is an aryl hydrocarbon receptor (AHR) antagonist.Cost-effective and quality-assured.Fórmula:C20H17ClFN3O3Pureza:99.46% - 99.85%Cor e Forma:SolidPeso molecular:401.82Ref: TM-T5622
1mg40,00€2mg50,00€5mg72,00€10mg115,00€25mg250,00€50mg424,00€100mg630,00€500mg1.320,00€1mL*10mM (DMSO)79,00€Phortress
CAS:Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumorFórmula:C20H25Cl2FN4OSPureza:100%Cor e Forma:SolidPeso molecular:459.41FICZ
CAS:FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM).Fórmula:C19H12N2OPureza:98.97%Cor e Forma:SolidPeso molecular:284.31ITE
CAS:ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.Fórmula:C14H10N2O3SPureza:97.91%Cor e Forma:SolidPeso molecular:286.31WAY-605471
CAS:WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.Fórmula:C14H15NO3S2Pureza:99.57%Cor e Forma:SolidPeso molecular:309.4Ref: TM-T9822
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€500mg2.157,00€1mL*10mM (DMSO)249,00€L-Kynurenine
CAS:L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan.Fórmula:C10H12N2O3Pureza:98.44% - 99.91%Cor e Forma:Light Yellow CrystallinePeso molecular:208.21Prochloraz
CAS:Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.Fórmula:C15H16Cl3N3O2Pureza:99.4%Cor e Forma:Colorless SolidPeso molecular:376.67KYN-101
CAS:KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.Fórmula:C22H19FN6Pureza:99.39%Cor e Forma:SolidPeso molecular:386.43Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Fórmula:C16H18N2OS·HBrPureza:100% - 98.54%Cor e Forma:SolidPeso molecular:367.3GNF351
CAS:GNF351: Full AHR antagonist, inhibits DRE-dependent/independent activity, low toxicity, binds AHR (IC50: 62 nM).Fórmula:C24H25N7Pureza:99.04%Cor e Forma:SolidPeso molecular:411.5Ref: TM-T15410
1mg44,00€5mg94,00€10mg144,00€25mg283,00€50mg520,00€100mg700,00€200mg945,00€1mL*10mM (DMSO)105,00€PDM2
CAS:PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.Fórmula:C14H9Cl3Pureza:99.44%Cor e Forma:SolidPeso molecular:283.58AHR Inhibitor I-103
CAS:AHR Inhibitor I-103 is an aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity used in the study of breast cancer and acute myeloid leukemia.Fórmula:C21H17FN6Pureza:98.64%Cor e Forma:SoildPeso molecular:372.4StemRegenin 1
CAS:StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.Fórmula:C24H23N5OSPureza:98% - 99.88%Cor e Forma:SolidPeso molecular:429.54
