PKM
A Piruvato Quinase M2 (PKM2) é uma isoforma da piruvato quinase que desempenha um papel crucial na glicólise, convertendo fosfoenolpiruvato em piruvato. PKM2 está envolvida na regulação da reprogramação metabólica em células cancerosas, tornando-se um alvo potencial para a terapia do câncer. Inibidores de PKM2 podem alterar as vias metabólicas, reduzir o crescimento tumoral e induzir a morte celular em células cancerígenas. Na CymitQuimica, oferecemos inibidores de PKM2 para apoiar sua pesquisa em metabolismo do câncer, oncologia e desenvolvimento terapêutico.
Produtos da "PKM"
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10 produtos desta categoria.
DASA-58
CAS:DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.Fórmula:C19H23N3O6S2Pureza:96.96% - 99.28%Cor e Forma:SolidPeso molecular:453.53PKM2-IN-1
CAS:PKM2-IN-1 (compound 3k) displays PKM2 inhibitory activity with the IC50 value of 2.95 μM. The IC50 value for PKM1 is 4-5-fold higher than that for PKM2.Fórmula:C18H19NO2S2Pureza:99.49% - 99.68%Cor e Forma:SolidPeso molecular:345.48Ref: TM-T4170
1mg40,00€2mg51,00€5mg85,00€10mg115,00€25mg205,00€50mg354,00€100mg567,00€200mg810,00€500mg1.216,00€PKM2 activator 2
CAS:PKM2 activator 2 is a pyruvate kinase M2 (PKM2) activator with an AC 50 value of 66 nM.PKM2 activator 2 has anti-tumor proliferative properties and attenuatesFórmula:C20H18F2N2O4S2Pureza:100%Cor e Forma:SolidPeso molecular:452.49Mitapivat sulfate hydrate
CAS:Mitapivat sulfate hydrate (AG 348 sulfate hydrate) is a pyruvate kinase (PK) allosteric activator, used to study pyruvate kinase deficiency.Fórmula:C24H26N4O3S1H2SO43H2OPureza:99.40%Cor e Forma:SolidPeso molecular:526.6Mitapivat
CAS:Mitapivat (PKR-IN-1), also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.Fórmula:C24H26N4O3SPureza:99.47% - 99.83%Cor e Forma:SolidPeso molecular:450.55TEPP-46
CAS:TEPP-46 (ML265) is an activator of pyruvate kinase M2 (PKM2), selective for PKM1, PKL and PKR. TEPP-46 has antitumor activity. Cost-effective and quality-assured.Fórmula:C17H16N4O2S2Pureza:98.21% - 98.77%Cor e Forma:SolidPeso molecular:372.46Ref: TM-T7214
1mg48,00€5mg96,00€10mg144,00€25mg235,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)96,00€PKM2 activator 5
CAS:PKM2 activator 5 is a novel and potent PKM2 activator (AC50: 0.316 µM) with potential anticancer activity for the study of cancer metabolism-related diseases.Fórmula:C18H19FN2O6S2Pureza:98%Cor e Forma:SolidPeso molecular:442.48Dimethylaminomicheliolide HCl
CAS:Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvateFórmula:C17H28ClNO3Pureza:99.55%Cor e Forma:SoildPeso molecular:329.86PKR-IN-2
CAS:PKR-IN-2 is a activator of pyruvate kinase (PKR).Fórmula:C24H28N4O4SPureza:99.14%Cor e Forma:SolidPeso molecular:468.57Ref: TM-T12499
1mg81,00€5mg145,00€10mg207,00€25mg334,00€50mg467,00€100mg655,00€200mg883,00€1mL*10mM (DMSO)149,00€PKM2 inhibitor G
CAS:PKM2 inhibitor G is a inhibitor of pyruvate kinase.Fórmula:C16H15NO3SPureza:99.54%Cor e Forma:SoildPeso molecular:301.36Ref: TM-T67900
1mg185,00€5mg425,00€10mg625,00€25mg938,00€50mg1.311,00€100mg1.795,00€1mL*10mM (DMSO)404,00€
