CETP
A CETP é uma proteína plasmática que facilita a transferência de ésteres de colesterol e triglicerídeos entre lipoproteínas, desempenhando um papel fundamental no metabolismo lipídico e na saúde cardiovascular. A inibição da CETP tem sido explorada como uma estratégia terapêutica para aumentar os níveis de colesterol HDL e reduzir o risco de doenças cardiovasculares. Na CymitQuimica, oferecemos inibidores de CETP para apoiar sua pesquisa em metabolismo lipídico, doenças cardiovasculares e desenvolvimento terapêutico.
Produtos da "CETP"
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16 produtos desta categoria.
Torcetrapib
CAS:Torcetrapib (CP-529414), a CETP inhibitor, curbs cholesteryl ester movement from HDL to LDL/VLDL; failed Phase III trials due to mortality increase.Fórmula:C26H25F9N2O4Pureza:98% - 99.59%Cor e Forma:LipidPeso molecular:600.47Obicetrapib
CAS:Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein.Fórmula:C32H31F9N4O5Pureza:100% - 99.26%Cor e Forma:SolidPeso molecular:722.6Implitapide
CAS:Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).Fórmula:C35H37N3O2Pureza:98%Cor e Forma:SolidPeso molecular:531.69Granotapide
CAS:Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolicFórmula:C39H37F3N2O8Pureza:100% - 99.34%Cor e Forma:SolidPeso molecular:718.71Ref: TM-T31992
1mg200,00€5mg504,00€10mg727,00€25mg1.121,00€50mg1.510,00€100mg2.043,00€500mg4.075,00€1mL*10mM (DMSO)740,00€CP-532623
CAS:CP-532623, a close structural analog of Torcetrapib, is a CETP inhibitor with highly lipophilic properties. It elevates high-density lipoprotein cholesterol.Fórmula:C27H27F9N2O3Pureza:98%Cor e Forma:SolidPeso molecular:598.5Anti-CETP Antibody (2H481)
Anti-CETP Antibody (2H481) is an antibody targeting CETP. Anti-CETP Antibody (2H481) can be used in ELISA, IHC.Cor e Forma:Odour LiquidEvacetrapib
CAS:Evacetrapib (LY2484595) inhibits CETP strongly (IC50=5.5 nM), raises HDL cholesterol, no rise in aldosterone/blood pressure. Phase 3.Fórmula:C31H36F6N6O2Pureza:98.53%Cor e Forma:SolidPeso molecular:638.65KD-026
CAS:KD-026 (SLx 4090), a microsomal triglyceride transfer protein (MTP) inhibitor(IC50 = 8.0 nM), is used in type 2 diabetes studies.Fórmula:C31H25F3N2O4Pureza:99.73%Cor e Forma:SolidPeso molecular:546.54Ref: TM-T27719
1mg81,00€2mg104,00€5mg170,00€10mg259,00€25mg444,00€50mg562,00€100mg775,00€200mg1.026,00€1mL*10mM (DMSO)210,00€Lomitapide Mesylate
CAS:Lomitapide Mesylate (BMS-201038 mesylate) is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.Fórmula:C40H41F6N3O5SPureza:99.65%Cor e Forma:SolidPeso molecular:789.83Ref: TM-T2545
1mg35,00€5mg65,00€10mg96,00€25mg144,00€50mg226,00€100mg340,00€200mg502,00€1mL*10mM (DMSO)96,00€20-HC-Me-Pyrrolidine
20-HC-Me-Pyrrolidine is a potent Aster protein inhibitor that blocks the ability of Aster proteins to bind and transfer cholesterol.Fórmula:C28H47NO2Pureza:99.99%Cor e Forma:SolidPeso molecular:429.68Dalcetrapib
CAS:Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.Fórmula:C23H35NO2SPureza:100% - 97.98%Cor e Forma:SolidPeso molecular:389.59Anacetrapib
CAS:Anacetrapib (MK-0859) inhibits rhCETP/CETP(C13S) (IC50: 7.9/11.8 nM), boosts HDL, lowers LDL cholesterol.Fórmula:C30H25F10NO3Pureza:98.40% - 99.62%Cor e Forma:SolidPeso molecular:637.51Ref: TM-T1928
2mg35,00€5mg52,00€10mg85,00€25mg138,00€50mg205,00€100mg300,00€200mg445,00€1mL*10mM (DMSO)74,00€TAP311
TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).Fórmula:C34H40F6N6O4Pureza:98%Cor e Forma:SolidPeso molecular:710.71Dirlotapide
CAS:Dirlotapide (CP742033), an intestinal MTP inhibitor, cuts weight in diabetic dogs by lowering food intake and raising peptide YY.Fórmula:C40H33F3N4O3Pureza:100% - 99.20%Cor e Forma:SolidPeso molecular:674.71Lomitapide
CAS:Lomitapide (AEGR-733) blocks MTP, a key enzyme in dietary lipid absorption and VLDL assembly.Fórmula:C39H37F6N3O2Pureza:98.91% - 99.40%Cor e Forma:SolidPeso molecular:693.72Ref: TM-T6267
2mg65,00€5mg95,00€10mg145,00€25mg230,00€50mg331,00€100mg499,00€200mg717,00€500mg1.103,00€1mL*10mM (DMSO)161,00€BMS-212122
CAS:BMS-212122 inhibits MTP, reduces lipids and plaque in animal tests.Fórmula:C43H36F6N4O2Pureza:99%Cor e Forma:SolidPeso molecular:754.76Ref: TM-T30506
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€
