GluR
Inibidores do Receptor de Glutamato são compostos que bloqueiam a atividade dos receptores de glutamato, os principais receptores de neurotransmissores excitatórios no cérebro. Esses receptores desempenham um papel crucial na transmissão sináptica, plasticidade, aprendizado e memória. A desregulação da sinalização do glutamato está associada a vários distúrbios neurológicos, como epilepsia, AVC e doenças neurodegenerativas. Os inibidores dos receptores de glutamato são essenciais para investigar os mecanismos de excitotoxicidade e desenvolver estratégias neuroprotetoras. Na CymitQuimica, oferecemos uma gama de inibidores de receptores de glutamato para apoiar sua pesquisa em função sináptica, neuroproteção e distúrbios cognitivos.
Produtos da "GluR"
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ADX88178
CAS:ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.Fórmula:C12H12N6SPureza:99.55%Cor e Forma:SolidPeso molecular:272.33Ref: TM-T4500
2mg38,00€5mg58,00€10mg96,00€25mg156,00€50mg243,00€100mg354,00€200mg505,00€1mL*10mM (DMSO)60,00€LY392098
CAS:LY392098 (AMPA receptor modulator-3) is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.Fórmula:C18H22FNO2SPureza:99.85%Cor e Forma:SolidPeso molecular:335.44Ref: TM-T27951
1mg42,00€5mg87,00€10mg140,00€25mg226,00€50mg324,00€100mg437,00€200mg605,00€1mL*10mM (DMSO)92,00€NS 1209
CAS:NS 1209 (SPD 502) is a AMPA receptor antagonist.Fórmula:C24H27N4NaO7SPureza:98%Cor e Forma:SolidPeso molecular:538.55PHCCC
CAS:PHCCC is a Group I mGluR antagonist and enhances mGluR4 function; also blocks mGluR2/8.Fórmula:C17H14N2O3Pureza:99.31%Cor e Forma:SolidPeso molecular:294.3(S)-3,4-DCPG HCl
(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.Fórmula:C10H10ClNO6Pureza:99.06% - 99.90%Cor e Forma:SoildPeso molecular:275.64Ref: TM-T23288L
1mg183,00€5mg462,00€10mg660,00€25mg1.035,00€50mg1.415,00€100mg1.872,00€500mg3.763,00€1mL*10mM (DMSO)415,00€Dasolampanel
CAS:Dasolampanel (NGX-426) is an ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders.Fórmula:C17H20ClN5O3Pureza:99%Cor e Forma:SolidPeso molecular:377.83VU0360172
CAS:VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).Fórmula:C18H15FN2OPureza:99.65%Cor e Forma:SolidPeso molecular:294.32Ref: TM-T29126
1mg57,00€5mg120,00€10mg187,00€25mg376,00€50mg588,00€100mg833,00€1mL*10mM (DMSO)115,00€XAP044
CAS:XAP044 blocks mGlu7, inhibiting long-term potentiation in mouse brain with a half-maximal effect at 88nm.Fórmula:C15H9IO4Pureza:97.41%Cor e Forma:SolidPeso molecular:380.13Ref: TM-T21995
1mg62,00€2mg87,00€5mg113,00€10mg207,00€25mg369,00€50mg557,00€100mg797,00€1mL*10mM (DMSO)155,00€DHPG
CAS:DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.Fórmula:C8H9NO4Pureza:99.55%Cor e Forma:SolidPeso molecular:183.16VU0361737
CAS:VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.Fórmula:C13H11ClN2O2Pureza:99.09% - 99.86%Cor e Forma:SolidPeso molecular:262.69Philanthotoxin 74 dihydrochloride
CAS:Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.Fórmula:C24H44Cl2N4O3Pureza:98.6%Cor e Forma:SolidPeso molecular:507.54CNQX
CAS:CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)Fórmula:C9H4N4O4Pureza:99.70%Cor e Forma:Pale Yellow SolidPeso molecular:232.15Ro 67-7476
CAS:Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors.Fórmula:C17H18FNO2SPureza:99.48%Cor e Forma:SolidPeso molecular:319.39Ref: TM-T3478
1mg35,00€2mg50,00€5mg93,00€10mg131,00€25mg258,00€50mg465,00€100mg680,00€1mL*10mM (DMSO)82,00€JNJ-46281222
CAS:JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.Fórmula:C23H25F3N4Cor e Forma:SolidPeso molecular:414.47Ref: TM-T8862
1mg37,00€5mg80,00€10mg116,00€25mg259,00€50mg383,00€100mg545,00€200mg740,00€1mL*10mM (DMSO)93,00€IDRA-21
CAS:IDRA-21 is a positive AMPA receptor modulator.Fórmula:C8H9ClN2O2SPureza:99.73%Cor e Forma:SolidPeso molecular:232.69DMeOB
CAS:DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.Fórmula:C16H16N2O2Pureza:98.34%Cor e Forma:SolidPeso molecular:268.31Ref: TM-T22736
1mg35,00€5mg70,00€10mg104,00€25mg202,00€50mg311,00€100mg472,00€500mg1.017,00€1mL*10mM (DMSO)85,00€JNJ-55511118
CAS:JNJ-55511118 is a TARP γ8 allosteric modulator with anticonvulsant activity, which can be used in research on chronic operant alcohol self-administration.Fórmula:C14H8ClF3N2O2Cor e Forma:SolidPeso molecular:328.67Pomaglumetad methionil hydrochloride
CAS:LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.Fórmula:C12H19ClN2O7S2Pureza:99.01%Cor e Forma:SolidPeso molecular:402.87Basimglurant
CAS:Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).Fórmula:C18H13ClFN3Pureza:98.35%Cor e Forma:SolidPeso molecular:325.77Ref: TM-T12717
1mg78,00€5mg169,00€10mg246,00€25mg406,00€50mg562,00€100mg702,00€200mg949,00€1mL*10mM (DMSO)178,00€3-MATIDA
CAS:3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).Fórmula:C8H9NO4SPureza:98.41% - 99.05%Cor e Forma:SolidPeso molecular:215.23KRP-199 sodium
KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.Fórmula:C22H12F3N5Na2O7Pureza:96.85%Cor e Forma:SoildPeso molecular:561.33Ref: TM-T27748L
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€500mg3.734,00€LY3020371 hydrochloride
CAS:LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.Fórmula:C15H16ClF2NO5SCor e Forma:SolidPeso molecular:395.81JNJ-46778212
CAS:JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.Fórmula:C20H17FN2O3Pureza:99.24%Cor e Forma:SolidPeso molecular:352.36A-794282
CAS:A-794282 is a selective antagonist of mGluR1.Fórmula:C19H18N4OSPureza:≥98%Cor e Forma:SolidPeso molecular:350.44GET73
CAS:GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5.Fórmula:C13H16F3NO2Pureza:99.54%Cor e Forma:SolidPeso molecular:275.27Ref: TM-T11393
1mg65,00€5mg131,00€10mg202,00€25mg340,00€50mg452,00€100mg638,00€200mg842,00€1mL*10mM (DMSO)177,00€γ-DGG
CAS:gamma-DGG is a competitive blocker of AMPA receptor.Fórmula:C7H12N2O5Pureza:98%Cor e Forma:SolidPeso molecular:204.18VU0483605
CAS:VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.Fórmula:C20H10Cl3N3O3Pureza:97.03%Cor e Forma:SolidPeso molecular:446.67Ref: TM-T21747
2mg42,00€5mg64,00€10mg97,00€25mg183,00€50mg284,00€100mg425,00€200mg562,00€1mL*10mM (DMSO)78,00€E4CPG
CAS:E4CPG is a novel group I/II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG.Fórmula:C11H13NO4Pureza:99.96%Cor e Forma:SolidPeso molecular:223.23L-AP4
CAS:L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).Fórmula:C4H10NO5PPureza:98%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:183.1LY-2300559
CAS:LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.Fórmula:C26H26O6Pureza:100%Cor e Forma:SolidPeso molecular:434.48Ref: TM-T27932
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€(S)-MCPG
CAS:(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.Fórmula:C10H11NO4Pureza:98.72%Cor e Forma:SolidPeso molecular:209.20VU 0357121
CAS:VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.Fórmula:C17H17F2NO2Pureza:99% - 99.99%Cor e Forma:SolidPeso molecular:305.32Fenobam
CAS:Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM).Fórmula:C11H11ClN4O2Pureza:99.93%Cor e Forma:SolidPeso molecular:266.68Ref: TM-T15275
1mg35,00€5mg64,00€10mg101,00€25mg170,00€50mg248,00€100mg359,00€200mg497,00€1mL*10mM (DMSO)96,00€DNQX
CAS:DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)Fórmula:C8H4N4O6Pureza:97.15% - 99.10%Cor e Forma:Off-White Powder With A Yellow TingePeso molecular:252.14JNJ-40411813
CAS:JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).Fórmula:C20H25ClN2OPureza:99.74%Cor e Forma:SolidPeso molecular:344.88Ref: TM-TQ0094
1mg55,00€5mg117,00€10mg183,00€25mg306,00€50mg437,00€100mg562,00€200mg743,00€1mL*10mM (DMSO)131,00€S 18986
CAS:S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties inFórmula:C10H12N2O2SPureza:99.25%Cor e Forma:SolidPeso molecular:224.281H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.Fórmula:C10H12N2O2SPureza:99.69%Cor e Forma:SoildPeso molecular:224.28VU0155041
CAS:VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).Fórmula:C14H15Cl2NO3Pureza:99.52% - 99.56%Cor e Forma:SolidPeso molecular:316.18Ref: TM-T3565
2mg40,00€5mg58,00€10mg85,00€25mg145,00€50mg188,00€100mg301,00€200mg435,00€1mL*10mM (DMSO)64,00€(S)-ATPO
CAS:(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.Fórmula:C11H19N2O7PPureza:98.37% - 99.41%Cor e Forma:SolidPeso molecular:322.25(RS)-3-Hydroxyphenylglycine
CAS:(RS)-3-Hydroxyphenylglycine is a PI-linked metabotropic glutamate receptors agonist.Fórmula:C8H9NO3Pureza:99.92%Cor e Forma:SolidPeso molecular:167.16MSOP
CAS:MSOP is a selective antagonist of group III metabotropic glutamate receptor (KD of 51 μM for the L-AP4-sensitive presynaptic mGluR).Fórmula:C4H10NO6PPureza:98%Cor e Forma:SolidPeso molecular:199.1ML337
CAS:ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.Fórmula:C21H20FNO3Pureza:99.09%Cor e Forma:SolidPeso molecular:353.39Ref: TM-T23003
1mg35,00€5mg64,00€10mg97,00€25mg207,00€50mg309,00€100mgA consultar1mL*10mM (DMSO)75,00€(RS)-MCPG
CAS:(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.Fórmula:C10H11NO4Pureza:99.96%Cor e Forma:SolidPeso molecular:209.2Ref: TM-T3479
1mg35,00€2mg48,00€5mg70,00€10mg87,00€25mg187,00€50mg338,00€100mg502,00€1mL*10mM (DMSO)74,00€Dipraglurant
CAS:Dipraglurant: a blood-brain permeable mGluR5 NAM, orally active, selective, IC50 = 21 nM, treats PD-LID.Fórmula:C16H12FN3Pureza:98.7%Cor e Forma:SolidPeso molecular:265.29Ref: TM-T15134
1mg97,00€5mg227,00€10mg329,00€25mg723,00€50mg1.064,00€100mg1.415,00€1mL*10mM (DMSO)274,00€VU6004909
CAS:VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.Fórmula:C21H15FN2O4Pureza:96.68% - 98.44%Cor e Forma:SolidPeso molecular:378.35Lu AF21934
CAS:Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).Fórmula:C14H16Cl2N2O2Pureza:97.96%Cor e Forma:SolidPeso molecular:315.2AMN082
CAS:AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis in rats with traumatic brain injury.Fórmula:C28H30Cl2N2Pureza:97.23% - 98.34%Cor e Forma:SolidPeso molecular:465.46NBQX Disodium
CAS:NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.Fórmula:C12H6N4Na2O6SPureza:98.22%Cor e Forma:SolidPeso molecular:380.24NBQX
CAS:NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.Fórmula:C12H8N4O6SPureza:97.66% - 99.42%Cor e Forma:SolidPeso molecular:336.28Ref: TM-T4113
1mg40,00€5mg89,00€10mg127,00€25mg246,00€50mg369,00€100mg525,00€200mg757,00€1mL*10mM (DMSO)87,00€LY 541850
CAS:LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from humanFórmula:C9H13NO4Pureza:98%Cor e Forma:SolidPeso molecular:199.2GYKI 53655 hydrochloride
CAS:GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.Fórmula:C19H21ClN4O3Pureza:98.02%Cor e Forma:SolidPeso molecular:388.85Foliglurax
CAS:Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).Fórmula:C23H23N3O3SPureza:98%Cor e Forma:SolidPeso molecular:421.51MFZ 10-7 hydrochloride
CAS:MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAMFórmula:C15H10ClFN2Pureza:98%Cor e Forma:SolidPeso molecular:272.71cis-PDA
CAS:cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.Fórmula:C7H11NO4Pureza:≥98%Cor e Forma:White SolidPeso molecular:173.17Decoglurant
CAS:Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.Fórmula:C21H11F6N5Pureza:99.77%Cor e Forma:SolidPeso molecular:447.34Ref: TM-T15090
1mg55,00€5mg117,00€10mg167,00€25mg309,00€50mg434,00€100mg605,00€200mg815,00€1mL*10mM (DMSO)160,00€VU 0364439
CAS:VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).Fórmula:C18H13Cl2N3O3SPureza:97.90%Cor e Forma:SolidPeso molecular:422.29CPPHA
CAS:CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.Fórmula:C22H15ClN2O4Pureza:99.61%Cor e Forma:SolidPeso molecular:406.82VU0155041 sodium
CAS:VU0155041 sodium is a positive allosteric modulator of mGluR4 that promotes extinction in male rats.Fórmula:C14H14Cl2NNaO3Pureza:98%Cor e Forma:SolidPeso molecular:338.16SIB-1757
CAS:SIB-1757 (6-methyl-2-[(E)-phenyldiazenyl]pyridin-3) is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)Fórmula:C12H11N3OPureza:97.37%Cor e Forma:SolidPeso molecular:213.24Ref: TM-T8434
2mg39,00€5mg58,00€10mg94,00€25mg170,00€50mg259,00€100mg363,00€200mg509,00€1mL*10mM (DMSO)77,00€FPTQ
CAS:FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1].Fórmula:C17H12FN5Pureza:99.68% - 99.88%Cor e Forma:SolidPeso molecular:305.31Ref: TM-T5509
1mg50,00€2mg73,00€5mg111,00€10mg160,00€25mg310,00€50mg419,00€100mg557,00€500mgA consultar1mL*10mM (DMSO)116,00€VU 0285683
CAS:VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.Fórmula:C14H7FN4OPureza:99.8%Cor e Forma:SolidPeso molecular:266.23Ref: TM-T23509
1mg42,00€5mg90,00€10mg101,00€25mg170,00€50mg235,00€100mg335,00€200mg455,00€1mL*10mM (DMSO)92,00€VU6005649
CAS:VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).Fórmula:C16H12F5N3OPureza:99.79%Cor e Forma:SolidPeso molecular:357.28Ref: TM-T13321
5mg40,00€10mg58,00€25mg105,00€50mg170,00€100mg259,00€200mg369,00€1mL*10mM (DMSO)44,00€VU-29
CAS:VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes.Fórmula:C22H16N4O3Pureza:99.63%Cor e Forma:SolidPeso molecular:384.39Ref: TM-T23515
2mg34,00€5mg52,00€10mg90,00€25mg170,00€50mg273,00€100mg393,00€200mg560,00€1mL*10mM (DMSO)58,00€CBiPES hydrochloride
CAS:CBiPES hydrochloride (CBiPES HCl) is an orthosteric modulator of the mGlu2 receptor and is used to study neurological disorders like epilepsy.Fórmula:C21H20ClN3O2SPureza:99.66%Cor e Forma:SolidPeso molecular:413.92TCN238
CAS:TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).Fórmula:C12H11N3Pureza:99.90%Cor e Forma:SolidPeso molecular:197.24VU0422288
CAS:VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.Fórmula:C17H11Cl2N3O2Pureza:95.48%Cor e Forma:SolidPeso molecular:360.19IEM 1754 2HBr
CAS:IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.Fórmula:C16H30N2·2HBrPureza:99.71% - 99.72%Cor e Forma:SolidPeso molecular:412.25NS-102
CAS:NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.Fórmula:C12H11N3O4Pureza:98.73% - 98.95%Cor e Forma:SolidPeso molecular:261.23TC-N 22A
CAS:TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier.Fórmula:C14H13N5SPureza:99.84%Cor e Forma:SolidPeso molecular:283.35ML289
CAS:ML289 is a potent CNS-penetrant mGlu3 modulator with IC50 of 0.66 μM, >15-fold selectivity over mGlu2, and inactive against mGlu5.Fórmula:C22H23NO3Pureza:99.09%Cor e Forma:SolidPeso molecular:349.42Ref: TM-T23000
5mg50,00€10mg80,00€25mg145,00€50mg225,00€100mg339,00€200mg470,00€1mL*10mM (DMSO)51,00€AZD6538
CAS:AZD6538 is an mGluR5 negative allosteric modulator used in the study of CNS-related diseases such as Alzheimer's disease.Fórmula:C15H6FN5OPureza:98.68%Cor e Forma:SolidPeso molecular:291.24MMPIP hydrochloride
CAS:MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.Fórmula:C19H16ClN3O3Pureza:99.26%Cor e Forma:SolidPeso molecular:369.8CX614
CAS:CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.Fórmula:C13H13NO4Pureza:97.43%Cor e Forma:SolidPeso molecular:247.25Ref: TM-T19698
5mg55,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€200mg409,00€1mL*10mM (DMSO)66,00€LY2794193
CAS:LY2794193, a potent and selective mGlu3 receptor agonist, reduces akathisia seizures and increases GAT1, GLAST and GLT-1 protein levels in rats.Fórmula:C16H18N2O6Pureza:98.15%Cor e Forma:SolidPeso molecular:334.32Ro 67-4853
CAS:Ro 67-4853 is a positive allosteric modulator of mGluR1, selectively enhancing the response to the agonist (S)-3,5-dihydroxy-phenylglycine (DHPG).Fórmula:C19H19NO4Pureza:98.57%Cor e Forma:SolidPeso molecular:325.36Caroverine hydrochloride
CAS:Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.Fórmula:C22H28ClN3O2Pureza:98.37% - 98.75%Cor e Forma:SolidPeso molecular:401.9Ref: TM-T9133
5mg47,00€10mg70,00€25mg131,00€50mg216,00€100mg378,00€200mg552,00€500mg868,00€1mL*10mM (DMSO)50,00€FTIDC
CAS:FTIDC: potent, selective mGluR1 allosteric antagonist, weak on mGluR5. IC50: human 5.8 nM, mouse 3.1 nM. Noncompetitive.Fórmula:C18H23FN6OPureza:≥98%Cor e Forma:SolidPeso molecular:358.41Ref: TM-T3483
1mg105,00€2mg154,00€5mg227,00€10mg359,00€25mg597,00€50mg842,00€100mg1.130,00€1mL*10mM (DMSO)250,00€ADX-47273
CAS:ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).Fórmula:C20H17F2N3O2Pureza:97% - 99.18%Cor e Forma:SolidPeso molecular:369.36Decanoic Acid
CAS:Decanoic Acid (Caprynic acid) acts as a non-competitive AMPA receptor antagonist.Fórmula:C10H20O2Pureza:98.59%Cor e Forma:Crystalline Solid SolidPeso molecular:172.26AZD 9272
CAS:AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.Fórmula:C14H6F2N4OPureza:97.53%Cor e Forma:SolidPeso molecular:284.22CX717
CAS:CX 717 is a positive allosteric modulator of AMPA receptor which has an antidepressant-like effect.Fórmula:C11H11N3O3Pureza:100%Cor e Forma:SoildPeso molecular:233.23LY-404187
CAS:LY404187 is a positive allosteric modulator of AMPA receptorsFórmula:C19H22N2O2SPureza:99.34%Cor e Forma:SolidPeso molecular:342.46Ref: TM-T7706
2mg35,00€5mg52,00€10mg90,00€25mg164,00€50mg239,00€100mg339,00€200mg472,00€1mL*10mM (DMSO)58,00€Cyclothiazide
CAS:Cyclothiazide enhances AMPA receptors, prevents desensitization, and boosts glutamic acid response (EC50 = 3.8µM).Fórmula:C14H16ClN3O4S2Pureza:98.23% - 99.49%Cor e Forma:Crystals From Dilute Alcohol SolidPeso molecular:389.88(S)-3-Hydroxyphenylglycine
CAS:(S)-3-Hydroxyphenylglycine is an agonist of group I metabotropic glutamate receptors (mGluRs).Fórmula:C8H9NO3Pureza:99.18%Cor e Forma:SolidPeso molecular:167.16JNJ16259685
CAS:JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19Fórmula:C20H23NO3Pureza:98.31%Cor e Forma:SolidPeso molecular:325.4Ref: TM-T5512
1mg48,00€2mg65,00€5mg90,00€10mg140,00€25mg293,00€50mg449,00€100mg655,00€1mL*10mM (DMSO)100,00€MPEP
CAS:MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.Fórmula:C14H11NPureza:99.54%Cor e Forma:SolidPeso molecular:193.24LSN2463359
CAS:LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.Fórmula:C16H15N3OPureza:99.36%Cor e Forma:SolidPeso molecular:265.31Ref: TM-T27854
2mg35,00€5mg52,00€10mg85,00€25mg170,00€50mg259,00€100mg383,00€200mg545,00€1mL*10mM (DMSO)58,00€VU0650786
CAS:VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.Fórmula:C18H15ClFN5O2Pureza:99.09%Cor e Forma:SolidPeso molecular:387.8Ref: TM-T13318
1mg96,00€5mg235,00€10mg329,00€25mg560,00€50mg800,00€100mg1.103,00€1mL*10mM (DMSO)259,00€FITM
CAS:FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).Fórmula:C18H18FN5OSPureza:97.25%Cor e Forma:SolidPeso molecular:371.43Ref: TM-T7292
1mg35,00€2mg47,00€5mg70,00€10mg97,00€25mg187,00€50mg283,00€100mg416,00€1mL*10mM (DMSO)65,00€VU0364770
CAS:VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGluFórmula:C12H9ClN2OPureza:99.65% - 99.92%Cor e Forma:SolidPeso molecular:232.67EGLU
CAS:EGLU, an antidepressant and potent mGluR-2 antagonist, binds with a 66 μM Kd to (lS,3S)-ACPD sites.Fórmula:C7H13NO4Pureza:99.98%Cor e Forma:SolidPeso molecular:175.18DCB
CAS:DCB is an mGluR5 allosteric ligand that blocks mGluR modulation, countering DMeOB and DFB effects.Fórmula:C14H10Cl2N2Pureza:99.12% - 99.9%Cor e Forma:SolidPeso molecular:277.15Ref: TM-T22711
5mg39,00€10mg50,00€25mg105,00€50mg170,00€100mg273,00€200mg378,00€1mL*10mM (DMSO)42,00€(E/Z)-SIB-1893
CAS:(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893.Fórmula:C14H13NPureza:99.92%Cor e Forma:SolidPeso molecular:195.26Org-26576
CAS:Org-26576 is a positive allosteric modulator of the AMPA receptor.Fórmula:C11H12N2O2Pureza:99.67%Cor e Forma:SolidPeso molecular:204.23Ref: TM-T16402
5mg47,00€10mg70,00€25mg104,00€50mg150,00€100mg256,00€200mg379,00€1mL*10mM (DMSO)50,00€Biphenylindanone A
CAS:Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.Fórmula:C30H30O4Pureza:98%Cor e Forma:SolidPeso molecular:454.56Piracetam
CAS:Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.Fórmula:C6H10N2O2Pureza:97.16%Cor e Forma:Crystals From Isopropanol SolidPeso molecular:142.16MTEP hydrochloride
CAS:MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)Fórmula:C11H9ClN2SPureza:99.58%Cor e Forma:SolidPeso molecular:236.72AMN082 free base
CAS:AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.Fórmula:C28H28N2Pureza:97.75% - 97.79%Cor e Forma:SolidPeso molecular:392.54Ref: TM-T21935L
1mg39,00€5mg78,00€10mg111,00€25mg216,00€50mg354,00€100mg567,00€200mg793,00€1mL*10mM (DMSO)89,00€VU-1545
CAS:VU-1545 is mGlu5 positive allosteric modulator.Fórmula:C22H15FN4O3Pureza:98.80%Cor e Forma:SolidPeso molecular:402.38
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