NMDAR
Os inibidores do receptor N-Metil-D-Aspartato (NMDAR) são compostos que bloqueiam a atividade dos NMDARs, um subtipo de receptores de glutamato que desempenham um papel crucial na plasticidade sináptica, no aprendizado e na memória. A superativação dos NMDARs está implicada na excitotoxicidade, que pode levar a danos neuronais e está associada a condições como AVC, lesão cerebral traumática e doenças neurodegenerativas. Os inibidores de NMDAR são ferramentas essenciais para estudar a excitotoxicidade e desenvolver terapias neuroprotetoras. Na CymitQuimica, oferecemos uma gama de inibidores de NMDAR para apoiar sua pesquisa em função sináptica, neuroproteção e distúrbios cognitivos.
Produtos da "NMDAR"
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DNQX disodium salt
CAS:DNQX disodium salt is a water-soluble form of selective antagonist of non-NMDA receptorFórmula:C8H2N4Na2O6Pureza:98.93%Cor e Forma:SolidPeso molecular:296.1Ref: TM-T8459
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)170,00€CGP 78608 hydrochloride
CAS:CGP 78608 hydrochloride: NMDA receptor antagonist (IC50=6 nM), anticonvulsant, enhances GluN1/GluN3A currents (EC50=26.3 nM).Fórmula:C11H14BrClN3O5PPureza:98.96% - 99.68%Cor e Forma:SolidPeso molecular:414.58Procyclidine hydrochloride
CAS:Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.Fórmula:C19H30ClNOPureza:99.95%Cor e Forma:Crystals From Petroleum Ether White PowderPeso molecular:323.9L-701324
CAS:L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.Fórmula:C21H14ClNO3Pureza:100% - 98.63%Cor e Forma:SolidPeso molecular:363.79Ro 25-6981 Maleate
CAS:Ro 25-6981 Maleate is an NMDA receptor antagonist used in the study of neurological disorders such as Parkinson's and epilepsy.Fórmula:C26H33NO6Pureza:99.42%Cor e Forma:SolidPeso molecular:455.54Lanicemine dihydrochloride
CAS:Lanicemine dihydrochloride (AZD-6765 dihydrochloride) is an NMDA channel blocker with antidepressant activity and can be used to study neurological diseases.Fórmula:C13H16Cl2N2Pureza:99.43%Cor e Forma:SolidPeso molecular:271.19Ref: TM-T60471
2mg35,00€5mg52,00€10mg93,00€25mg170,00€50mg283,00€100mg432,00€500mg938,00€1mL*10mM (DMSO)47,00€TCS 46b
CAS:TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.Fórmula:C22H23N3OPureza:99% - 99.81%Cor e Forma:SolidPeso molecular:345.44GNE-8324
CAS:GNE-8324 is a GluN2A selective positive allosteric modulator that enhances NMDAR-mediated synaptic responses in inhibitory, but not excitatory, neurons.Fórmula:C18H18FN3OSPureza:98.68% - 99.34%Cor e Forma:SolidPeso molecular:343.42Ref: TM-T31981
1mg150,00€5mg359,00€10mg532,00€25mg848,00€50mg1.121,00€100mg1.539,00€200mg2.072,00€1mL*10mM (DMSO)368,00€Rapastinel Trifluoroacetate
CAS:Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties.Fórmula:C20H32F3N5O8Pureza:99.01% - 99.77%Cor e Forma:SolidPeso molecular:527.49Ref: TM-T5819
1mg39,00€5mg101,00€10mg170,00€25mg305,00€50mg419,00€100mg562,00€200mg743,00€1mL*10mM (DMSO)116,00€Traxoprodil
CAS:Traxoprodil (CP101606) is a selective NMDA antagonist and protects hippocampal neurons (IC50: 10 nM).Fórmula:C20H25NO3Pureza:99.89%Cor e Forma:SolidPeso molecular:327.42Nandrolone decanoate
CAS:Nandrolone decanoate is an anabolic steroid similar to testosterone, stimulating muscle, bone growth, and red blood cell production.Fórmula:C28H44O3Pureza:98.43% - 99.03%Cor e Forma:SolidPeso molecular:428.65GV-196771A
CAS:GV-196771A A novel NMDA receptor glycine site antagonist with potent antinociceptive activity.Fórmula:C20H13Cl2N2NaO3Pureza:96.43%Cor e Forma:SolidPeso molecular:423.23Eliprodil
CAS:Eliprodil (SL-820715), NR2B-NMDA receptor blocker (IC50: 1 uM), less potent on NR2A/NR2C (IC50>100 uM), explored for Parkinson's and movement issues.Fórmula:C20H23ClFNOPureza:97.56% - 99.77%Cor e Forma:SolidPeso molecular:347.85N-Methyl-DL-aspartic acid
CAS:N-Methyl-DL-aspartic acid, a glutamate analogue and NMDA receptor agonist, is utilized in neurological disease research.Fórmula:C5H9NO4Pureza:99.62%Cor e Forma:SolidPeso molecular:147.136-Methoxy-2-naphthoic acid
CAS:6-Methoxy-2-naphthoic acid (6-Methoxy-2-naphthalenecarboxylic acid) is an modulator of NMDAR.Fórmula:C12H10O3Pureza:99.25%Cor e Forma:White To Off-White Powder Crystals Crystalline Powder And/Or ChunksPeso molecular:202.21
