Células - tronco e Derivados
Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.
Subcategorias de "Células - tronco e Derivados"
- Gama-secretase
- Hedgehog/Smoothened
- Via Hippo
- JAK
- Porcupine
- ROCK
- STAT
- Células - tronco
- TGF-beta/Smad
- Wnt/beta-catenina
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Produtos da "Células - tronco e Derivados"
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AZD2858
CAS:AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway.Fórmula:C21H23N7O3SPureza:98% - 99.25%Cor e Forma:SolidPeso molecular:453.52Ref: TM-T1957
1mg38,00€2mg49,00€5mg79,00€10mg106,00€25mg198,00€50mg374,00€100mg555,00€500mg1.206,00€1mL*10mM (DMSO)108,00€RU-SKI 43
CAS:RU-SKI 43: Potent, selective Hhat inhibitor, IC50 850 nM. Anticancer; potential lung adenocarcinoma treatment. Inhibits Gli-1, Akt, mTOR pathways.Fórmula:C22H30N2O2SPureza:99.78%Cor e Forma:SolidPeso molecular:386.55Epiblastin A
CAS:Epiblastin A inhibits CK1, targets its isoenzymes, and converts EpiSCs to cESCs.Fórmula:C12H10ClN7Pureza:99.45%Cor e Forma:SolidPeso molecular:287.71Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Fórmula:C20H28ClN7O3SPureza:99.23%Cor e Forma:SolidPeso molecular:482SMANT hydrochloride
CAS:SMANT hydrochloride (N-(4-bromophenyl)-3-(3,5-dimethylpiperidin-1-yl)propanamide hydrochloride) is an antagonist of Smoothened accumulation.Fórmula:C16H24BrClN2OPureza:100%Cor e Forma:SolidPeso molecular:375.73Disitertide acetate
Disitertide acetate: a TGF-β1 and PI3K blocker, promotes apoptosis; inhibits receptor interaction.Fórmula:C70H113N17O24S2Pureza:95.11%Cor e Forma:SoildPeso molecular:1640.88IWP-3
CAS:IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1γ3 and CK1ε, but does not inhibit CK1α [1] [2].Fórmula:C22H17FN4O2S3Pureza:98.38%Cor e Forma:SolidPeso molecular:484.59GSK180736A
CAS:GSK180736A: GRK2 inhibitor (IC50 0.77µM), >100x selectivity vs GRKs, weak at PKA (IC50 30µM), strong vs ROCK1 (IC50 100nM).Fórmula:C19H16FN5O2Pureza:98.16% - 98.44%Cor e Forma:SolidPeso molecular:365.36Ref: TM-T3513
1mg42,00€2mg52,00€5mg73,00€10mg88,00€25mg170,00€50mg306,00€100mg568,00€500mg1.225,00€1mL*10mM (DMSO)65,00€Tolnaftate
CAS:Tolnaftate (NP-27) is a synthetic antifungal agent.Fórmula:C19H17NOSPureza:98.85%Cor e Forma:White PowderPeso molecular:307.41MSC-4106
CAS:MSC-4106, an oral YAP/TAZ-TEAD inhibitor, blocks TEAD1/3 auto-palmitoylation and suppresses NCI-H226 tumors.Fórmula:C18H12F3N3O2Pureza:100%Cor e Forma:SoildPeso molecular:359.3Ref: TM-T60148
1mg96,00€5mg235,00€10mg378,00€25mg630,00€50mg898,00€100mg1.216,00€200mg1.634,00€1mL*10mM (DMSO)271,00€Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Fórmula:C20H27N7O3SPureza:98.74% - 99.49%Cor e Forma:SolidPeso molecular:445.54Ref: TM-T2487
1mg44,00€2mg55,00€5mg79,00€10mg106,00€25mg185,00€50mg283,00€100mg432,00€200mg605,00€500mg938,00€1mL*10mM (DMSO)86,00€Tofacitinib Citrate
CAS:Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).Fórmula:C22H28N6O8Pureza:99.19% - 99.75%Cor e Forma:SolidPeso molecular:504.49TAK-901
CAS:TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among othersFórmula:C28H32N4O3SPureza:97.38% - 99.1%Cor e Forma:SolidPeso molecular:504.64AR-A014418
CAS:AR-A014418 (GSK 3β inhibitor VIII) is an ATP-competitive, and selective GSK3β inhibitor.Fórmula:C12H12N4O4SPureza:99.94% - ≥95%Cor e Forma:SolidPeso molecular:308.31Aloisine B
CAS:Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively.Fórmula:C15H14ClN3Pureza:95.15%Cor e Forma:SolidPeso molecular:271.74Tubastatin
CAS:Tubastatin inhibits TGF-β1-induced S6K phosphorylation, HIF-1α expression and VEG F expression.Fórmula:C21H22N2O2Pureza:98.23%Cor e Forma:SolidPeso molecular:334.41Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Fórmula:C20H26O5Pureza:100% - 99.74%Cor e Forma:SolidPeso molecular:346.42Ref: TM-T4672
1mg96,00€5mg215,00€10mg369,00€25mg610,00€50mg840,00€100mg1.130,00€500mg2.308,00€1mL*10mM (DMSO)235,00€PIMPC
CAS:PIMPC, a compound endowed with antioxidant and metal-chelating properties, acts as a novel inhibitor of glycogen synthase kinase 3 (GSK-3), and exhibitsFórmula:C21H19N5OPureza:98%Cor e Forma:SolidPeso molecular:357.41Rhodblock 6
CAS:Rhodblock 6 is a Rho kinase inhibitor, blocking phosphorylated MRLC localization by targeting ROCK activity.Fórmula:C12H13N3OPureza:98.27%Cor e Forma:SolidPeso molecular:215.25Wnt/β-catenin agonist 2
CAS:Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and is an effective Wnt agonist.Fórmula:C13H12N4O3Pureza:99.58%Cor e Forma:SolidPeso molecular:272.26Ref: TM-T41094
1mg54,00€5mg116,00€10mg187,00€25mg318,00€50mg449,00€100mg638,00€500mg1.264,00€1mL*10mM (DMSO)111,00€
