Células - tronco
Os inibidores de células-tronco são compostos que atuam especificamente nas células-tronco e em suas vias de sinalização, afetando sua capacidade de autorrenovação e diferenciação. Esses inibidores são cruciais em pesquisas focadas no controle do comportamento das células-tronco, na compreensão dos processos de desenvolvimento e no desenvolvimento de terapias para doenças como o câncer, onde se acredita que as células-tronco desempenhem um papel fundamental. Na CymitQuimica, oferecemos uma variedade de inibidores de células-tronco para apoiar sua pesquisa em medicina regenerativa, biologia do desenvolvimento e oncologia.
Produtos da "Células - tronco"
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GDC-0214
CAS:GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Fórmula:C28H28ClF2N9O3Pureza:98.54%Cor e Forma:SolidPeso molecular:612.03Ref: TM-T9826
1mg87,00€5mg192,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€200mg1.159,00€1mL*10mM (DMSO)259,00€XL413 xHCl
CAS:BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215Fórmula:C14H12ClN3O2·xHClPureza:99.42% - 99.67%Cor e Forma:SolidPeso molecular:326.18VT104
CAS:VT104 is a potent and orally active YAP/TAZ inhibitor for cancer research.Cost-effective and quality-assured.Fórmula:C25H19F3N2OPureza:99.43% - 99.5%Cor e Forma:SolidPeso molecular:420.43Ref: TM-T67872
1mg79,00€5mg243,00€10mg394,00€25mg640,00€50mg898,00€100mg1.206,00€1mL*10mM (DMSO)225,00€RKI1313
CAS:RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasionFórmula:C17H16N4O2SPureza:99.06% - ≥95%Cor e Forma:SolidPeso molecular:340.4VT107
CAS:VT107 is a potent pan-TEAD autopalmitoylation inhibitor. VT-107 can be used in cancer therapy research.Cost-effective and quality-assured.Fórmula:C25H20F3N3OPureza:98.43% - 99.73%Cor e Forma:SolidPeso molecular:435.44Ref: TM-T35545
1mg137,00€5mg329,00€10mg502,00€25mg810,00€50mg1.103,00€100mg1.483,00€200mg1.985,00€1mL*10mM (DMSO)360,00€Pentabromophenol
CAS:Pentabromophenol (NSC-5717) suppressed TGF-β response by accelerating the turnover rate of TGF-β receptors.Fórmula:C6HBr5OPureza:98.89%Cor e Forma:Monoclinic Prisms From Acetic Acid; Needles From Alcohol Physical Description Light Brown Powder Insoluble In Water (Ntp 1992)Peso molecular:488.59dCK1α-2
dCK1α-2 is an orally effective CK1α molecular glue (Molecular Glue) degrader that targets p53 pathway-related targets. It demonstrates antitumor efficacy in mouse models by enhancing the expression of p53-related genes.Fórmula:C24H24ClN5O4Cor e Forma:SolidPeso molecular:481.93GSK-3β inhibitor 11
CAS:GSK-3β inhibitor 11 (compound 21) is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β) with an inhibitory concentration (IC50) of 10.02 μM.Fórmula:C20H15N3O4SPureza:97.33%Cor e Forma:SolidPeso molecular:393.42BRD5648
CAS:BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705.Fórmula:C20H23N3OPureza:99.37%Cor e Forma:SolidPeso molecular:321.42JLK6
CAS:JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signallingFórmula:C10H8ClNO3Pureza:96.50%Cor e Forma:SolidPeso molecular:225.63Ref: TM-T21890
1mg131,00€5mg259,00€10mg371,00€25mg622,00€50mg885,00€100mg1.206,00€500mg2.403,00€1mL*10mM (DMSO)271,00€Linavonkibart
CAS:Linavonkibart (SRK181) is a humanized antibody targeting TGFβ1 that blocks the release of TGF-β1 protein by specifically binding latent TGF-β1.Pureza:95% - 95%Cor e Forma:LiquidXMU-MP-1
CAS:XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2.Fórmula:C17H16N6O3S2Pureza:99.68% - 99.68%Cor e Forma:SolidPeso molecular:416.48Ref: TM-T4212
1mg52,00€2mg79,00€5mg97,00€10mg153,00€25mg305,00€50mg512,00€100mg740,00€1mL*10mM (DMSO)95,00€STAT3-IN-36
CAS:STAT3-IN-36 (compound 11g) is a tritarget inhibitor that selectively targets LRPPRC, STAT3, and CDK1, exhibiting potent anticancer activity. This compound binds to LRPPRC, STAT3, and CDK1, demonstrating more effective anticancer effects than those of TMF or Capecitabine. Additionally, STAT3-IN-36 exhibits an IC50 value of 1.8 μM in HGC27 cells.Fórmula:C30H24F2N2O9S2Cor e Forma:SolidPeso molecular:658.65SSTC3
CAS:SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.Fórmula:C23H17F3N4O3S2Pureza:98.65%Cor e Forma:SolidPeso molecular:518.53GSK269962A
CAS:GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.Fórmula:C29H30N8O5Pureza:99.14% - 99.71%Cor e Forma:SolidPeso molecular:570.6Akt/ROCK-IN-1
Akt/ROCK-IN-1 (B12) is a dual inhibitor targeting Akt and ROCK, exhibiting IC50 values of 0.023 nM and 1.47 nM, respectively.Fórmula:C21H19BrF2N4O2SPureza:98%Cor e Forma:SolidPeso molecular:509.37JAK-IN-11
CAS:JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.Fórmula:C23H22FN5O4SPureza:99.57%Cor e Forma:SolidPeso molecular:483.52CWP232228
CAS:CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Fórmula:C33H34N7Na2O7PPureza:96.13%Cor e Forma:SolidPeso molecular:717.63GSK-3 Inhibitor XIII
CAS:GSK-3 InhibitorXIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.Fórmula:C18H15N5Pureza:100% - 98.57%Cor e Forma:SolidPeso molecular:301.35SJ000291942
CAS:SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.Fórmula:C16H15FN2O4Pureza:99.66%Cor e Forma:SolidPeso molecular:318.3
