c-Fms
Os inibidores de c-Fms têm como alvo o Receptor do Fator Estimulador de Colônias-1 (c-Fms), uma tirosina quinase envolvida na regulação de macrófagos e outras células imunológicas. A sinalização de c-Fms desempenha um papel na proliferação, diferenciação e sobrevivência dessas células. A desregulação do c-Fms está associada a doenças como câncer, condições inflamatórias e osteoporose. Na CymitQuimica, oferecemos inibidores de c-Fms para apoiar sua pesquisa em imunologia, oncologia e doenças inflamatórias.
Produtos da "c-Fms"
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CSF1R Protein, Human, Recombinant (Domain I&II&III, His)
CSF1R Protein, Human, Recombinant (Domain I&II&III, His) is expressed in HEK293 mammalian cells with His tag.Cor e Forma:Lyophilized PowderPeso molecular:31.1 kDa (predicted)Anti-CSF1R Antibody (5C535)
Anti-CSF1R Antibody (5C535) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (5C535) can be used in ELISA.Cor e Forma:Odour LiquidGW2580
CAS:GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.Fórmula:C20H22N4O3Pureza:100% - 99.86%Cor e Forma:SolidPeso molecular:366.41c-Fms-IN-1
CAS:c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).Fórmula:C22H27N5O2Pureza:99.88%Cor e Forma:SolidPeso molecular:393.48CSF1R-IN-3
CAS:CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM.Fórmula:C30H38N8O4Pureza:97.31%Cor e Forma:SolidPeso molecular:574.67Ref: TM-T64066
1mg106,00€5mg259,00€10mg378,00€25mg702,00€50mg1.026,00€100mg1.473,00€1mL*10mM (DMSO)325,00€CSF1R-IN-1
CAS:CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.Fórmula:C25H20F3N5O2Pureza:97.02% - 98.56%Cor e Forma:SolidPeso molecular:479.45Ref: TM-T10894
1mg94,00€5mg210,00€10mg325,00€25mg550,00€50mg787,00€100mg1.093,00€200mg1.454,00€1mL*10mM (DMSO)230,00€CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag.Cor e Forma:Lyophilized PowderPeso molecular:83.04 kDa (predicted); 110.87 kDa (reducing conditions)Anti-CSF1R Antibody (1R707)
Anti-CSF1R Antibody (1R707) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (1R707) can be used in ELISA.Cor e Forma:Odour LiquidAZD7507
CAS:AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.Fórmula:C23H27FN6O3Pureza:98.01% - 99.09%Cor e Forma:SolidPeso molecular:454.5Ref: TM-T14380
1mg52,00€5mg116,00€10mg170,00€25mg305,00€50mg442,00€100mg615,00€200mg832,00€1mL*10mM (DMSO)134,00€IACS-9439
CAS:IACS-9439 is a potent, selective, and orally active inhibitor of CSF1R, exhibiting a K(i) of 1 nM.Fórmula:C23H26ClN7O3SPureza:98%Cor e Forma:SolidPeso molecular:516.02PLX647
CAS:PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).Fórmula:C21H17F3N4Pureza:99.38%Cor e Forma:SolidPeso molecular:382.38Ref: TM-T1925
2mg42,00€5mg60,00€10mg90,00€25mg134,00€50mg188,00€100mg279,00€200mg411,00€1mL*10mM (DMSO)64,00€CSF1R Protein, Human, Recombinant (hFc)
CSF1R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:81.2 kDa (predicted)
