Receptor de Melatonina
Los receptores de ácido lisofosfatídico (LPA) son un grupo de GPCR que responden al LPA, un lípido bioactivo involucrado en la proliferación, migración y supervivencia celular. La señalización de LPA juega un papel crucial en varios procesos fisiológicos, incluyendo la cicatrización de heridas, el desarrollo vascular y la metástasis del cáncer. La modulación de la actividad de los receptores de LPA se está explorando para aplicaciones terapéuticas en el cáncer, la fibrosis y las enfermedades inflamatorias. En CymitQuimica, ofrecemos una gama de moduladores de receptores de LPA de alta calidad para apoyar su investigación en señalización celular, oncología y trastornos inflamatorios.
Produtos da "Receptor de Melatonina"
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14 produtos desta categoria.
Melatonin
CAS:Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.Fórmula:C13H16N2O2Pureza:98% - 99.79%Cor e Forma:Pale Yellow Leaflets From Benzene SolidPeso molecular:232.28Melatonin-Tamoxifen Conjugate
Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.Fórmula:C47H58N4O4Cor e Forma:SolidPeso molecular:742.99N-ACETYLTRYPTAMINE
CAS:N-ACETYLTRYPTAMINE is a partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase.Fórmula:C12H14N2OPureza:98.79%Cor e Forma:PowderPeso molecular:202.25Ramelteon
CAS:Ramelteon (TAK-375) is a Melatonin Receptor Agonist. The mechanism of action of ramelteon is as a Melatonin Receptor Agonist.Fórmula:C16H21NO2Pureza:97.21% - 99.92%Cor e Forma:Crystalline SolidPeso molecular:259.34Ref: TM-T1463
2mg44,00€5mg65,00€10mg88,00€25mg136,00€50mg202,00€100mg325,00€500mg512,00€1mL*10mM (DMSO)71,00€4-P-PDOT
CAS:4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.Fórmula:C19H21NOPureza:99.68%Cor e Forma:SolidPeso molecular:279.386-Chloromelatonin
CAS:6-Chloromelatonin: potent, stable melatonin agonist; binds MT2 receptors (pKi=9.77); could help research sleep disorders.Fórmula:C13H15ClN2O2Pureza:97.90% - 99.36%Cor e Forma:SolidPeso molecular:266.72Ref: TM-T22530
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€ACH-000143
CAS:ACH-000143 是一种可口服的褪黑素受体激动剂,对 MT1 和 MT2 的EC50值分别为0.06 和0.32 nM。Fórmula:C13H16ClN3O3Pureza:98.15%Cor e Forma:SolidPeso molecular:297.74Ref: TM-T9193
1mg52,00€5mg116,00€10mg182,00€25mg320,00€50mg449,00€100mg615,00€200mg830,00€1mL*10mM (DMSO)128,00€Tasimelteon
CAS:Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.Fórmula:C15H19NO2Pureza:98.08% - 99.93%Cor e Forma:SolidPeso molecular:245.322-Iodomelatonin
CAS:2-Iodomelatonin, Ki 28 pM, is an MT1 agonist, >5x selective over MT2, used to map melatonin sites in brain/tissues.Fórmula:C13H15IN2O2Pureza:100%Cor e Forma:SolidPeso molecular:358.17Ref: TM-T10073
10mg46,00€25mg84,00€50mg125,00€100mg188,00€200mg283,00€500mgA consultar1mL*10mM (DMSO)35,00€Nedemelteon
CAS:Nedemelteon is an agonist of the melatonin receptor (melatonin receptor).Fórmula:C15H18N2O2Cor e Forma:SolidPeso molecular:258.32UCM 608
CAS:UCM 608 (2-Phenylmelatonin) is an antagonist of melatonin-induced contractile responses at low concentrations and induces an increase in GDP-GTP exchange.Fórmula:C19H20N2O2Pureza:98.88%Cor e Forma:SolidPeso molecular:308.37Agomelatine
CAS:Agomelatine (Valdoxan), like melatonin, boosts mood by targeting melatonin and 5-HT2C receptors.Fórmula:C15H17NO2Pureza:99.92%Cor e Forma:White SolidPeso molecular:243.3S26131
CAS:S26131 (N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide) behaves as an antagonist on MT1 and MT2 receptors with Ki ofFórmula:C31H34N2O4Pureza:99.69%Cor e Forma:SolidPeso molecular:498.61Luzindole
CAS:Luzindole (N-0774) is a selective melatonin receptor antagonist.Fórmula:C19H20N2OPureza:98.53%Cor e Forma:Off-White Amorphous SolidPeso molecular:292.37Ref: TM-T15795
1mg51,00€5mg144,00€10mg236,00€25mg399,00€50mg587,00€100mg832,00€500mg1.663,00€1mL*10mM (DMSO)156,00€
