Síntese de DNA/RNA
Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.
Produtos da "Síntese de DNA/RNA"
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NKP-1339
CAS:NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.Fórmula:C14H12Cl4N4NaRuPureza:98%Cor e Forma:SolidPeso molecular:502.14MTH1 ligand 1
CAS:MTH1 ligand 1 functions as a target protein ligand for MTH1, and is utilized in the synthesis of PROTACaTAG 2139.Fórmula:C23H18N4O3Cor e Forma:SolidPeso molecular:398.41Levofloxacin
CAS:Levofloxacin ((-)-Ofloxacin) is a synthetic fluoroquinolone antibiotic that prevents DNA replication. Cost-effective and quality-assured.Fórmula:C18H20FN3O4Pureza:98.14% - 99.80%Cor e Forma:Off-White To Yellow CrystalsPeso molecular:361.37Nolatrexed dihydrochloride
CAS:Nolatrexed dihydrochloride (Thymitaq) is a soluble, lipophilic cancer drug that inhibits DNA replication, causing cell cycle arrest and apoptosis.Fórmula:C14H14Cl2N4OSPureza:97.02%Cor e Forma:Tan SolidPeso molecular:357.26Anisomycin
CAS:Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.Fórmula:C14H19NO4Pureza:98.33% - 99.81%Cor e Forma:White Crystalline SolidPeso molecular:265.3DI-87
CAS:DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.Fórmula:C23H30N6O3S2Pureza:99.76%Cor e Forma:SolidPeso molecular:502.65Phleomycin
CAS:Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage.Fórmula:C48H69N17O20S2Pureza:98%Cor e Forma:SolidPeso molecular:1268.29Mithramycin A
CAS:Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of variousFórmula:C52H76O24Pureza:99.28%Cor e Forma:Yellow PowderPeso molecular:1085.15WRN inhibitor 1
CAS:WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain.Fórmula:C16H13FN2O4SPureza:98%Cor e Forma:SolidPeso molecular:348.35Dithranol
CAS:Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especiallyFórmula:C14H10O3Pureza:93.49% - ≥98%Cor e Forma:Physical Description Lemon Yellow Leaflets Or Plates Or An Orange Powder MeltingPeso molecular:226.23Amenamevir
CAS:Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mLFórmula:C24H26N4O5SPureza:99.00% - 99.86%Cor e Forma:SolidPeso molecular:482.55Ref: TM-T4226
1mg60,00€2mg79,00€5mg124,00€10mg197,00€25mg325,00€50mg505,00€100mg730,00€500mg1.501,00€1mL*10mM (DMSO)140,00€BWC0977
CAS:BWC0977 is an effective topoisomerase inhibitor that disrupts bacterial DNA replication by targeting both DNA gyrase and topoisomerase IV. The minimum inhibitory concentration (MIC90) of BWC0977 against MDR (multi-drug resistant) Gram-negative bacteria ranges from 0.03 to 2 µg/mL.Fórmula:C22H21FN6O5Cor e Forma:SolidPeso molecular:468.44GSK_WRN4
CAS:GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer researchFórmula:C16H20N2O4SPureza:100%Cor e Forma:SolidPeso molecular:336.41Brr2-IN-2
Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.Fórmula:C21H25FN4O2Cor e Forma:SolidPeso molecular:384.45Dihydromyricetin
CAS:Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.Fórmula:C15H12O8Pureza:96.68% - 98.13%Cor e Forma:SolidPeso molecular:320.25IMT1B
CAS:IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.Fórmula:C24H21ClFNO6Pureza:98.26% - 99.64%Cor e Forma:SolidPeso molecular:473.88Ref: TM-T8842
1mg145,00€5mg311,00€10mg533,00€25mg775,00€50mg938,00€100mg1.320,00€1mL*10mM (DMSO)325,00€CeMMEC1
CAS:CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).Fórmula:C19H16N2O4Pureza:100% - 99.26%Cor e Forma:SolidPeso molecular:336.34Sorivudine
CAS:Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.Fórmula:C11H13BrN2O6Pureza:97.33%Cor e Forma:SolidPeso molecular:349.13Adenine hemisulfate
CAS:Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistryFórmula:(C5H5N5)·H2SO4Pureza:99.78%Cor e Forma:White To Light Yellow Crystal PowderPeso molecular:368.336-Hydroxy-DOPA
CAS:6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.Fórmula:C9H11NO5Pureza:96.59% - 97.23%Cor e Forma:SolidPeso molecular:213.19
