Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Produtos da "Sinalização Citoesquelética"
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PKCθ pseudosubstrate peptide inhibitor,myristoylated
Myristoylated PKCθ pseudosubstrate peptide inhibitor is a synthetic peptide utilized to investigate the mechanism of action of protein kinase C theta (PKCθ) [1Fórmula:C105H184N36O21SPureza:98%Cor e Forma:SolidPeso molecular:2318.88Miransertib
CAS:Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor.Fórmula:C27H24N6Pureza:98.83% - ≥95%Cor e Forma:SolidPeso molecular:432.52Ref: TM-T3467
1mg52,00€5mg97,00€10mg169,00€25mg344,00€50mg567,00€100mg908,00€500mg1.795,00€1mL*10mM (DMSO)114,00€Defactinib hydrochloride
CAS:Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.Fórmula:C20H22ClF3N8O3SPureza:98.06% - 98.78%Cor e Forma:SolidPeso molecular:546.95Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Fórmula:C35H30N4O4Pureza:100% - 99.47%Cor e Forma:SolidPeso molecular:570.64Ref: TM-T3211
1mg51,00€5mg88,00€10mg126,00€25mg216,00€50mg328,00€100mg487,00€500mg1.093,00€1mL*10mM (DMSO)96,00€LY3372689
CAS:LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.Fórmula:C16H22FN5O3SPureza:99.27% - 99.45%Cor e Forma:SolidPeso molecular:383.44Ref: TM-T61661
1mg99,00€5mg235,00€10mg354,00€25mg635,00€50mg935,00€100mg1.415,00€1mL*10mM (DMSO)259,00€Multi-kinase inhibitor 1
CAS:Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Fórmula:C20H17F3N4O3Pureza:99.34%Cor e Forma:SolidPeso molecular:418.37FRAX597
CAS:FRAX597 is an effective, ATP-competitive inhibitor of group I PAKs, and for PAK1(IC50=8 nM), PAK2(IC50=13 nM), and PAK3 (IC50=19 nM).Fórmula:C29H28ClN7OSPureza:97.34% - 99.85%Cor e Forma:SolidPeso molecular:558.1Ansamitocin P 3'
CAS:Ansamitocin P 3' (Maytansinol butyrate) is an antibody-drug conjugate cytotoxin with antitumor activity.Fórmula:C32H43ClN2O9Pureza:98.16% - 99.16%Cor e Forma:SolidPeso molecular:635.14Ref: TM-T1910
2mg34,00€5mg50,00€10mg84,00€25mg145,00€50mg229,00€100mg340,00€200mg472,00€1mL*10mM (DMSO)70,00€Ifebemtinib
CAS:Ifebemtinib (BI-853520) is an adhesion plaque kinase inhibitor with anti-tumour activity for the study of breast cancer.Fórmula:C28H28F4N6O4Pureza:98.07% - 99.82%Cor e Forma:SolidPeso molecular:588.55Ionomycin calcium
CAS:Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.Fórmula:C41H70CaO9Pureza:98% - 98.11%Cor e Forma:SolidPeso molecular:747.07NAMI-A
CAS:NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.Fórmula:C8H15Cl4N4ORuSPureza:98%Cor e Forma:SolidPeso molecular:458.18Ipfencarbazone
CAS:Ipfencarbazone herbicide agent, is a substance being developed for the control of weeds such as watergrass in rice.Fórmula:C18H14Cl2F2N4O2Cor e Forma:SolidPeso molecular:427.23Dynapyrazole A
CAS:Dynapyrazole A inhibits dynein 1 and 2 (IC50s: 2.3, 2.6 μM) and Hedgehog signaling (IC50: 1.9 μM).Fórmula:C20H12ClIN4OPureza:98.01%Cor e Forma:SolidPeso molecular:486.69RWJ 50271
CAS:RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Fórmula:C18H17F3N4O2SPureza:99.09%Cor e Forma:SolidPeso molecular:410.41Ref: TM-T12783
1mg127,00€5mg311,00€10mg472,00€25mg747,00€50mg1.017,00€100mg1.311,00€200mg1.786,00€1mL*10mM (DMSO)344,00€AMP-945
CAS:AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.Fórmula:C28H32F3N5O2Pureza:99.60%Cor e Forma:SolidPeso molecular:527.58Ref: TM-T9576
1mg97,00€5mg188,00€10mg311,00€25mg533,00€50mg755,00€100mg1.035,00€1mL*10mM (DMSO)254,00€Etrolizumab
CAS:MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.Pureza:95% - 95%Cor e Forma:LiquidAdhesamine diTFA
CAS:Adhesamine diTFA, a dumbbell-shaped molecule, activates the MAPK/FAK pathway. It promotes adhesion and growth in mammalian cells and accelerates differentiation and enhances the survival rate of primary cultured mouse hippocampal neurons.Fórmula:C28H32Cl2F6N8O6S2Cor e Forma:SolidPeso molecular:825.63BX-2819
CAS:BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .Fórmula:C21H24N4O4SPureza:98%Cor e Forma:SolidPeso molecular:428.51αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).Fórmula:C28H35F3N6O8SPureza:98%Cor e Forma:SolidPeso molecular:672.67Hydroxy-Dynasore
CAS:Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,Fórmula:C18H14N2O5Pureza:100% - 97.60%Cor e Forma:SolidPeso molecular:338.31Ref: TM-T6822
5mg50,00€10mg84,00€25mg137,00€50mg221,00€100mg329,00€200mg490,00€500mg783,00€1mL*10mM (DMSO)55,00€
