Heterociclos com Nitrogénio (N)

Applications 1-(2,2-Dihydroxyethyl)-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic Acid is an intermediate in the synthesis of Bictegravir-15N, d2 (B382096), which is the labeled version of Bictegravir, which is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM. References Tsiang M. et al.: Antimicrob Agents Chemother. 2016 Nov 21;60(12):7086-7097;

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2-Cyano-5-hydroxypyridine (2C5HP) is a synthetic compound that has been shown to have a glucose lowering effect in diabetic rats. It has also been found to be an agonist of the nicotinic acetylcholine receptor, suggesting that it may be useful for treating Alzheimer's disease and other neurodegenerative disorders. 2C5HP is a member of the class of compounds known as piperidines.

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Applications 4-Bromo-7H-pyrrolo[2,3-d]pyrimidine

Please enquire for more information about 4-Methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)piperidine dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

(9H-Fluoren-9-yl)methyl2,4-dichloro-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate is a prodrug that is metabolized to the active form of the drug, 9-[(fluorenylmethoxy)carbonyl]-2,4-dichloro-7,8-dihydropyrido[4,3-d]pyrimidine. This compound binds to receptors in the pancreas and gastrointestinal tract and reduces gastric acid secretion. It also has significant binding to receptors in the nervous system. The drug may be used for treatment of pancreatic disorders such as diabetes mellitus. It may also be used for treatment of gastrointestinal disorders such as peptic ulcers or gastritis. The drug has been shown to reduce symptoms associated with nervous system disorders such as Parkinson's disease or

2,6-Dichloropyridine-4-carboxaldehyde is a synthetic compound that is an aldehyde. It can be used to synthesize 7-deazapurine through dehydration. The oxidation products of 2,6-Dichloropyridine-4-carboxaldehyde are isonicotinic acid and the corresponding alcohol. The reaction time for this compound is kinetic and it has been shown to have homologous reactivity with purines. Electrospray ionization was used to analyze the reactivity of this compound and other related compounds in order to determine its active site.