Heterociclos com Nitrogénio (N)

Applications 2,​3-​Cyclopentenopyridine is used as reactant/reagent for ruthenium-mediated dual catalytic reactions of isoquinoline via C-H activation and dearomatization for isoquinolone. References Wang, T., et al.: Adv. Synth. Catal., 358, 2751-2758 (2016)

Applications N-Chloropiperidine is an intermediate used in the synthesis of 1-Piperidin-2-ylacetone (B449983), which is a useful research chemical.

Applications Reagent used to prepare biosynthetic polymer surfactants designed for shear-stable endothelialization. References Schaefer, A., et al.: J. Bacteriol., 178, 2897 (1996), Ruegsegger, M., et al.: J. Biomed. Mat. Res., 56, 159 (2001), Abdu-Allah, H., et al.: J. Med. Chem., 51, 6665 (2008), Georgiades, S., et al.: Bioorg. Med. Chem. Lett., 18, 3117 (2008),

3-(2-Pyridyl)-5,6-di(p-sulfophenyl)-1,2,4-triazinedisodiumsalt hydrate is a synthetic iron chelator that has been used in Chinese herbology as an acetate extract. The water vapor extracts of the plant have shown to have a strong effect on the polymerase chain reaction (PCR) and anion radical scavenging activity. 3-(2-Pyridyl)-5,6-di(p-sulfophenyl)-1,2,4-triazinedisodiumsalt hydrate is also effective in human serum and plasma mass spectrometry for the determination of iron binding. It has been shown to have a pH optimum range between 6.0 and 7.5, with maximum activity at pH 7.0. The monosodium salt form of 3-(2-Pyridyl)-5,6-di(p-sulfophen

(R)-4-Boc-2-methylpiperazine is a picolinamide dehydrogenase inhibitor that is used to treat type 2 diabetes. It has been shown to reduce blood glucose levels in animal models and human subjects with type 2 diabetes mellitus. The mechanism of action is thought to be via inhibition of the 11β-hydroxysteroid dehydrogenase, which increases insulin sensitivity. This drug also has good oral bioavailability, does not cause weight gain, and has an acceptable safety profile.

2-Methoxy-3,5-dimethylpyrazine is a synthetic compound that can be used as a wastewater treatment agent. It has been shown to be effective in the removal of geosmin and other volatile organic compounds from wastewater. 2-Methoxy-3,5-dimethylpyrazine can be obtained by a chromatographic method or by a solid phase microextraction technique. The compound has not been found to have any health effects or toxic properties, but it does produce some structural isomers. Spectrometric data can be collected using this compound and the analytical methods are available for low detection levels and high sensitivity. The analytical methods use gas chromatography, mass spectrometry, or nuclear magnetic resonance spectroscopy.

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4-(Trifluoromethyl)pyridine-2-carboxylic acid is an organic compound with the formula C(CF3)HNO2. It is a colorless solid that is soluble in organic solvents. This compound has been used as a ligand to study the electronic spectra of metal ions in solution. 4-(Trifluoromethyl)pyridine-2-carboxylic acid has been shown to have a dipole, which causes it to be polar and thus able to form hydrogen bonds with other molecules. The molecule has two different resonance structures, which are square planar and optical. The functional theory was used to describe this molecule's spectrum, which was observed using a spectrometer and the solvent effect on this molecule's spectrum was also noted.

5-Bromoindole is a fine chemical that is used as a building block in organic synthesis.

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Applications 4-(Difluoromethoxy)piperidine (cas# 1147107-39-8) is a useful research chemical.

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2,4,6,8-Tetrahydroxypyrimido[5,4-d]pyrimidine is an organic compound that contains a carbonyl group. It has two nitrogen atoms and four hydrogen bonds. This molecule is also chiral and exhibits stereoisomerism. 2,4,6,8-Tetrahydroxypyrimido[5,4-d]pyrimidine is used as an herbicide to control broadleaf weeds in wheat crops. The structure of this compound is monoclinic with the space group P2/c. This molecule has a molecular weight of 162.24 g/mol and a melting point of 183 °C. 2,4,6,8-Tetrahydroxypyrimido[5,4-d]pyrimidine can be neutralized by acid or base.

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2-Aminopyrimidine-5-carboxylic acid is a biochemical that belongs to the class of amides. It has been shown to inhibit the aggregation of beta-amyloid (Aβ) and reduce the formation of Aβ plaques in an animal model for Alzheimer's disease. 2-Aminopyrimidine-5-carboxylic acid inhibits binding of dl-methionine to its receptors in rat cerebral cortex, which may be due to its ability to inhibit guanine nucleotide exchange factors. This agent also has agonist potency at m1 receptors and has been shown to inhibit the release of noradrenaline from synaptosomes. 2-Aminopyrimidine-5-carboxylic acid also has a luminescent property, which may be useful for detection purposes.

3-Hydroxyisoquinoline is a non-nucleoside inhibitor of cyclic nucleotide phosphodiesterase (cNMP) that is used in the treatment of nervous system diseases. 3-Hydroxyisoquinoline has been shown to have an inhibitory effect on cyclic nucleotide phosphodiesterase and can be used for the treatment of neurological disorders such as Parkinson’s disease, Alzheimer’s disease, and epilepsy. It also has anti-inflammatory properties and can be used to treat pain. 3-Hydroxyisoquinoline has a photoelectron spectrum that peaks at 5.6 eV, with a strong absorption band at 2.1 eV due to hydrogen bonding. This compound is also able to absorb radiation in the form of light emission with an emission peak at 4.8 eV, with a maximum intensity around 830 nm and a half-life of 0.2 s. 3-Hydroxyisoquinoline is able to

2-Amino-3,5-dinitropyridine (2ADNP) is a synthetic compound that has been shown to inhibit the human immunodeficiency virus (HIV) by inhibiting the b-Raf kinase. It binds to the acidic region of b-Raf and prevents it from binding to protonated amino acids in its ATP-binding pocket. 2ADNP also inhibits the activity of other kinases, including those that are involved in cellular signal transduction pathways. The incorporation of 2ADNP into cells leads to a reduction in viral production, which is associated with a decrease in the levels of HIV RNA and protein expression. This drug also has antiviral effects against hepatitis C virus, herpes simplex virus type 1, and influenza A virus.

Applications 6-Methyl-2,3'-bipyridine (cas# 78210-78-3) is a useful research chemical.

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Imidazo[1,2-a]pyridin-2-yl-methylamine dihydrochloride is a fine chemical that is used as an intermediate in the synthesis of various compounds. It has been found to be an excellent building block for complex compounds and useful scaffold for a variety of research chemicals. Imidazo[1,2-a]pyridin-2-yl-methylamine dihydrochloride is also a reaction component that can be used in the synthesis of speciality chemicals and pharmaceuticals. Imidazo[1,2-a]pyridin-2-yl-methylamine dihydrochloride is soluble in water and methanol and can be stored at room temperature. This product has a CAS number of 452967-56-5.

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Applications Pyridine-15N, is the labeled analogue of Pyridine (P991280), a basic six-membered heterocyclic ring. Pyridine is a base structure present in many biologically active compounds like the vitamins niacin and pyridoxal. Pyridine is used in dehalogenation reactions and can be used as a base in condensation reactions. References Egyed, J. et al.: Bull. Soc. Chim. Fra., 11, 3014 (1973); Li, Y. et al.: Wuli HUa. Xueb., 14, 1048 (1998);

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Applications 2,2,5,5-Tetramethyl-2,5-dihydro-1H-pyrrolo-3-acetic Acid (cas# 76194-00-8) is a compound useful in organic synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

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2-(3-Pyrazin-2-yl-1,2,4-oxadiazol-5-yl)ethyl]amine hydrochloride is a pyridylmethyl derivate with the formula CHN. It has an acetamide group at the 2 position of the pyridine ring. This compound is soluble in water, methanol and ethanol.

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