Heterociclos com Nitrogénio (N)

Please enquire for more information about 2,6-Difluoropyridine-4-boronic acid pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

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3-(Piperidin-4-yloxy)pyridine is an arylboronic acid that binds to both nicotinic and muscarinic acetylcholine receptors. The affinity of 3-(Piperidin-4-yloxy)pyridine for the acetylcholine receptor is about 10 times greater than its affinity for the nicotinic receptor. This molecule can be used as a pharmacological tool to study the function of these two types of acetylcholine receptors in vitro. 3-(Piperidin-4-yloxy)pyridine may also be used as a starting material for the synthesis of other molecules, such as pyridines.

Stability Hygroscopic Applications 4-Diphenylmethoxypiperidine, HCl

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Tenatoprazole is a prodrug that is converted to its active form, 2-mercapto-5-methoxyimidazole-[4,5-b]pyridine (TMP), in the stomach. Tenatoprazole inhibits gastric acid secretion by binding to the H/K ATPase enzyme in the parietal cells of the stomach and prevents the release of hydrogen ions into the stomach. TMP also inhibits gastric acid secretion by inhibiting histamine release from enterochromaffin cells and blocking calcium channels. This drug has been shown to be effective for treating peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome.

Please enquire for more information about N-[2-Nitro-4-(Trifluoromethyl)Phenyl]Piperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Bromo-4-nitropyridine is a molecule that contains a polarizability, hydrogen bond, and molecular electrostatic potential. It has been used to study the effects of solvent on the stability of molecules. X-ray data from 2-bromo-4-nitropyridine was collected at the Argonne National Laboratory. The molecular electrostatic potential was calculated using quantum chemistry calculations and vibrational spectroscopy data. The homoconjugation in 2-bromo-4-nitropyridine is due to its acetonitrile group and nitro group, which are both electron donating groups. 2-Bromo-4-nitropyridine has been synthesized using synthetic chemistry with dipole bonds cleaving during the reaction.

Please enquire for more information about 4-Chloro-5-iodo-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Please enquire for more information about Methyl {4-[(tert-butoxycarbonyl)amino]piperidin-1-yl}acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-(Chloromethyl)-2-(4-fluorophenyl)pyridine is a compound that has been shown to have potential use in bladder cancer. It is currently under investigation and not yet approved for clinical use. This drug binds to the toll-like receptor 4 (TLR4) on cancer cells, which triggers a proinflammatory response. TLR4 activation induces the production of cytokines such as IL-6, IL-8, and TNF-α by tumor cells, leading to increased inflammation in the bladder. 4-(Chloromethyl)-2-(4-fluorophenyl)pyridine also inhibits muscle cell proliferation and causes malignant changes in bladder cells. The compound has been shown to be effective against muscle tissue, but not nonmuscle tissue.

1-Butyl-1-methylpiperidinium bromide is a pyridinium salt with the chemical formula C6H14BrN. It is a colorless liquid with a high vapor pressure. 1-Butyl-1-methylpiperidinium bromide has been shown to be an effective extractant for chloride ions and can be used in the extraction of corilagin, which is a polyphenolic compound found in plant cell walls. The Langmuir adsorption isotherm for this compound shows that it has an optimum extraction process at pH 3 and a maximum adsorption capacity of 2.2 mg/g. This compound reacts with hydrochloric acid to produce hydrogen bromide, which in turn reacts with chlorine gas to form hydrobromic acid. 1-Butyl-1-methylpiperidinium bromide also undergoes photoelectron spectroscopy, which identifies its chemical structures

Please enquire for more information about 2-Amino-3-cyano-4-methyl-5-iodopyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-(Chloromethyl)-6-methylpyridine is a nonheme iron complex. It has been shown to bind to the metal ion in the active site of pyridine nitrogenase, a key enzyme in the formation of porphyrin. The binding may be due to a combination of coordination and oxidation, as well as ligand-metal charge transfer. The crystal structure of 2-(chloromethyl)-6-methylpyridine was determined using x-ray crystallography. The molecule has an octahedral geometry and consists of two planar pyramidal groups with pyridine nitrogen atoms on opposite sides and methyl groups on the other two corners. The molecule can also exist as an n-oxide or tetranuclear species, where oxygen or phosphorus oxychloride are bound to each corner respectively.

Please enquire for more information about 3-[(4-Methylpiperazin-1-yl)carbonyl]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Diethyl(pyridin-​4-​yl)​borane is a powerful reducing agent used in the synthesisof non-basic compounds as factor Xa inhibitors. Diethyl(pyridin-​4-​yl)​borane is used for the synthesis of 4-aryl- and 4-heteroarylpyridines by the palladium-catalyzed cross-coupling reaction. References Komoriya, S. et al.: Bioorg. Med. Chem. 13, 3927 (2005); Ishikura, Minoru., et al.: Chem. Pharm. Bull., 33, 4755(1985)

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4-Methylpyrimidine is a molecule used in the treatment of cancer. It is an inhibitor of the enzyme topoisomerase II, which is involved in DNA replication and repair. 4-Methylpyrimidine binds to the active site of topoisomerase II and blocks its activity. 4-Methylpyrimidine has been shown to be effective against Covid-19 pandemic, which was responsible for a severe outbreak of pneumonia in 2009. The reaction mechanism of 4-methylpyrimidine involves methylpyrazine, a chloride ligand, and molybdenum as the metal center. FT-IR spectroscopy has been used to identify the structural analysis of this molecule.