Heterociclos com Nitrogénio (N)

Applications An intermediate in the synthesis of rabeprazole (R070500).

Applications 3-aminoisoxazole-4-carbonitrile (cas# 258518-65-9) is a useful research chemical.

6-Bromopyridine-3,4-diamine is a chemical compound that can be used to make other products. It can be synthesized by reacting phosphorus with brominating agents such as stannous chloride or chlorine. This reaction produces 6-bromopyridine-3,4-diamine and the target product, which is a methanol solution of stannous chloride peroxide. The chemical is used in the production of many different products, including plastics, dyes, and pharmaceuticals.

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Applications Can be used in the preparation of substances for treatment of dermatological conditions and skin protection.

Applications 5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydro-2H-Benzimidazole-2-thione is used in the preparation of triclabendazoles which are drugs used to treat liver fluke. References Iddon, B., et al.:Journal of the Chemical Society 22, 3129 (1992);

N-(1-Oxyl-2,2,6,6-tetramethyl-4-piperidinyl)maleimide (TTFA) is a reactive molecule that belongs to the class of maleimides. TTFA has been shown to be stable in physiological levels and is not toxic at low concentrations. TTFA binds to serine protease enzymes and inhibits their activity. This inhibition can be used as a model for the inhibition of influenza virus replication by serine proteases. TTFA inhibits translation in a variety of model systems, including yeast, bacteria and mammalian cells. TTFA also inhibits mitochondrial protein synthesis in a model system with rat liver mitochondria and human leukemia cells. In addition, TTFA inhibits fatty acid biosynthesis in yeast cells. The reactivity of this molecule makes it useful for studying the dynamics of protein folding under physiological conditions.

5-Pyridin-2-yl-1,3,4-oxadiazole-2-thiol is a synthetic compound that has been shown to have anticancer properties in vitro. It inhibits the mitochondrial electron transport chain by binding to the mitochondrial membrane and inhibiting the enzyme cytochrome c oxidase. This leads to an accumulation of reactive oxygen species and induction of apoptosis in cancer cells. 5-Pyridin-2-yl-1,3,4-oxadiazole-2-thiol also inhibits luminescence properties of picolinic acid with anions. The primary function of this compound is to inhibit cancer cell growth by causing them to undergo apoptosis. 5PYRODS also binds to mitochondria and blocks the electron transport chain. This leads to an accumulation of reactive oxygen species (ROS) and the induction of apoptosis in cancer cells. 5PYRODS also inhibits luminescence properties of picolin

Applications 5-Bromo-2-methoxy-4,6-dimethyl-pyrimidine can be synthesized from 4,6-Dimethyl-2-hydroxypyrimidine (D476275), a component of Nicarbazine (N394530). References Ksenija Sinigoj, G., et al.: Slovenski Kemijski Dnevi, (2012); Kyung-Woo, L., et al.: Han'guk Kagum Hakhoechi, 39, 17 (2012);

2-Amino-6-methylpyrazine is a synthetic compound that has antiinflammatory properties. It is a competitive inhibitor of the enzyme cyclooxygenase, which is responsible for producing prostaglandins in the body. 2-Amino-6-methylpyrazine has been studied in various assays and shown to have antiinflammatory activity at doses of 5 mg/kg. The compound also inhibits carboxylic acid production by blocking the enzyme carbonic anhydrase. 2-Amino-6-methylpyrazine has not been tested on humans, but its safety profile is expected to be similar to other NSAIDs like indomethacin and ibuprofen.

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1-Propylpiperazine dihydrobromide is an amide with a piperazine ring. It has a homologous structure to other amides and is considered a crosslinking agent. 1-Propylpiperazine dihydrobromide can be used as a crosslinker in polymers. The solubility parameters for this compound are quite large, which indicates that it is hydrophobic and acidic. 1-Propylpiperazine dihydrobromide can be used at various temperatures, with the solution temperature of this compound being in the range of -40°C to 100°C. The activation energy for 1-Propylpiperazine dihydrobromide is approximately 16 kcal/mol, whereas the thermodynamic properties are not well studied. This compound has been shown to have transport mechanism properties that are dependent on pH, nature of solvent, and temperature.

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4-Fluoro-2-methoxypyridine is an organic compound that has two functional groups: one is a hydroxyl group and the other is a nitro group. It can be prepared by cleaving ethers with hydrofluoric acid and reacting the resulting alkyl halides with trimethylsilyl chloride. 4-Fluoro-2-methoxypyridine can also be synthesized by treatment of uracil with n-oxide in the presence of a base. The drug has been used in preparations to treat tuberculosis, leprosy, and malaria.

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4-Isopropylpyrimidin-2-amine is a chemical compound that has been studied for its ability to inhibit the enzyme hydrolase. It has been shown to be an inhibitor of soluble epoxide hydrolase and epoxide hydrolase, which are enzymes that break down arachidonic acid. 4-Isopropylpyrimidin-2-amine has also been shown to have cardiovascular and cardiovascular disorders properties, as well as anti-diabetic effects. This drug is an amide with a pharmacophore model that includes a basic nitrogen atom, with two hydrogen atoms attached to it, and three methyl groups on the other side of the nitrogen atom.

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1-Benzyl-4-oxo-piperidine-3-carboxylic acid is an alkyl ester that is also a chiral compound. It is synthesized from the reaction of benzaldehyde with 1,1'-carbonyldiimidazole in the presence of copper(II) chloride as a catalyst. The product is purified by recrystallization from ethyl acetate and hexanes, followed by distillation. This compound has been shown to catalyze the transfer of hydrogen and other organic molecules into water during phase transfer.

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4-Aminopiperidin-1-yl)acetic acid hydrochloride is a radionuclide that has been used to study the receptor subtype of the human pancreas. This drug has been shown to have antagonistic properties and high affinity for the receptor. 4-Aminopiperidin-1-yl)acetic acid hydrochloride may be useful in treating cancer, although further testing is required. 4APAAH binds to receptors by means of a ligand and can be tagged with a radioactive isotope for imaging purposes.