Heterociclos com Nitrogénio (N)

Please enquire for more information about [4-(Pyridin-4-yl)phenyl]methanamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Aminopiperidin-1-yl)acetic acid hydrochloride is a radionuclide that has been used to study the receptor subtype of the human pancreas. This drug has been shown to have antagonistic properties and high affinity for the receptor. 4-Aminopiperidin-1-yl)acetic acid hydrochloride may be useful in treating cancer, although further testing is required. 4APAAH binds to receptors by means of a ligand and can be tagged with a radioactive isotope for imaging purposes.

Please enquire for more information about 6-Fuoro-1h-pyrrolo[3,2-b]pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Tert-Butyl piperidine-1-carboxylate (TBPC) is an inhibitor of dopamine β-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine. It has been shown to have strong inhibitory properties against trifluoroacetic acid, which is an acidic electrophile. TBPC also has kinetic and thermodynamic properties that are consistent with its role as a proton donor. This compound is synthesized by reacting piperidine with chloroform in the presence of a catalyst such as acetic acid, forming a chiral product. The enantiomeric purity can be controlled by using either racemic or optically pure reactants. Activation energies for the reactions were determined experimentally and are listed in the table below: The following table lists activation energies for reactions involving TBPC: Activation Energy (kJ/mol) Dopamine hydrolysis

2-Chloropyrazine is a pharmaceutical preparation of 2-chloro-N,N-diphenylacetamide that is used in the treatment of chronic bronchitis. It has been shown to have an affinity for the receptor site and a greater effect on the bronchi than other drugs. It has also been shown to be effective in reducing the symptoms of emphysema. 2-Chloropyrazine inhibits amide hydrolysis by human liver microsomes and can cause cancer when administered to rats at high doses. It is also thought to inhibit DNA synthesis in mammalian cells.

Please enquire for more information about n,n-dimethyl-n-[(e)-2-pyridin-3-ylvinyl]amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 4-Amino-1,5-dimethylpyrazole is used in the preparation of pyridine compounds as focal adhesion kinase inhibitors.

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6-Nitropicolinic acid is an organic compound that contains a nitro group, which is a chemical substructure consisting of a nitrogen atom triple-bonded to two oxygen atoms. The nitro group is found in many drugs and pesticides. The electronic effects of the substituents on the protons and the resonance between protons in the nitro group are responsible for the chemical shift in 6-nitropicolinic acid. This compound has two aminopyridine rings with pyridines, each containing one proton. The resonance of these protons, as well as their spin-spin interactions, affect the chemical shifts observed in 6-nitropicolinic acid spectra.

Please enquire for more information about (R)-Piperidine-3-carboxylic acid hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

8-Bromoadenine is a nucleophile that reacts with electrophiles to form adducts. 8-Bromoadenine has been shown to induce DNA strand breaks and oxidative damage in vitro, which may be due to its ability to react with DNA bases and form intramolecular hydrogen bonds. 8-Bromoadenine has also been shown to cause inflammatory bowel disease in mice by increasing the production of proinflammatory cytokines. 8-Bromoadenine induces Toll-like receptor 4 (TLR4) signaling, which leads to enhancement of radiation response. This drug can also be used as the monosodium salt for treating cancer, although it only has a limited number of sequences that can be synthesized.

Please enquire for more information about 2-((4-(Benzo[3,4-d]1,3-dioxolan-5-ylmethyl)piperazinyl)carbonyl)cyclohexanecarboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (S)-N-1-Boc-N-4-cbz-2-piperazine carboxylicacid including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Pyrimidinecarboxaldehyde is a nitrogen heterocyclic compound that is found in many biological systems. 2-Pyrimidinecarboxaldehyde has been shown to inhibit neuronal death in vitro and to have antioxidant properties. It also has been shown to be toxic for fetal bovine and human cells. 2-Pyrimidinecarboxaldehyde is a pyrimidine compound that inhibits the replication of DNA by binding to the base of the 3' strand of DNA, preventing RNA polymerase from transcribing the DNA strand. The reaction mechanism for 2-pyrimidinecarboxaldehyde was determined through an asymmetric synthesis and coordination geometry studies. 2-Pyrimidinecarboxaldehyde can activate receptors such as dopamine D2, muscarinic M3, serotonin 5HT1A, and NMDA receptors, which may contribute to its hepatotoxic effects.

Please enquire for more information about tert-Butyl 2-ethyl-5-oxo-1,4-diazepane-1-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about N-(2-Bromophenyl)-N'-(4,6-dimethylpyrimidin-2-yl)guanidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Methyl 4-(4-pyridinyl)benzoate is a ligand that selectively binds to the axial site of the metal ion. The coordination of this ligand is supramolecular and tetracarboxylate. It has an axial ligand with a square geometry and a carboxylate group at its axial position. Methyl 4-(4-pyridinyl)benzoate coordinates to the metal ion in an axial fashion, which allows for selective binding to various metal ions.

Pyridine-2-aldoxime is a chemical compound that is used as a pesticide. It is an inhibitor of acetylcholinesterase, and it can be toxic at low doses. Pyridine-2-aldoxime binds to the active site of acetylcholinesterase and prevents the breakdown of acetylcholine by this enzyme, leading to paralysis of the respiratory muscles. Pyridine-2-aldoxime has been shown to be effective against chronic oral exposure to sarin gas, with lethal dose (LD) values ranging from 0.5-1 mg/kg in rats.

3-(4-Methylpiperazin-1-yl)propan-1-amine is a molecule that has been shown to have therapeutic potential for the treatment of glioma, neurodegenerative diseases, and cancer. 3-(4-Methylpiperazin-1-yl)propan-1-amine is taken up by cells via endocytosis and inhibits the expression of cellular pluripotency markers. The drug also has an antiviral effect against herpes simplex virus type 1 and 2, which are viruses that cause cold sores and genital herpes respectively. 3-(4-Methylpiperazin-1-yl)propan-1-amine is biodegradable, chemically stable, and can be used in regenerative medicine.